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Featured
Advancements in the Treatment of Neurodegenerative Disease
In this video, Ghazaleh Sadri-Vakili, PhD, director of the NeuroEpigenetics Laboratory and the MassGeneral Institute of Neurodegenerative Disease, discusses her genetic research, specifically concerning neurodegenerative diseases like ALS and X-linked dystonia parkinsonism.
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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Featured
Identifying New Potential Therapeutic Targets for ALS FTD
Transcripts of repeat expansions in the C90RF72 gene undergo a repeat-associated non-AUG (RAN) translation pathway that generates multiple aberrant proteins. Researchers at Mass General Hospital identified new potential therapeutic targets for ALS FTD.
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Lunasin Does Not Slow ALS Progression
In a pilot study, lunasin did not affect progression of amyotrophic lateral sclerosis (ALS), but the innovative trial design resulted in the fastest enrollment rate in ALS history, with excellent retention and adherence.
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Review: The Cerebellum and Cognition
Jeremy D. Schmahmann, MD, director of the Ataxia Unit at Massachusetts General Hospital, discusses the advances in the rapidly growing field of the clinical cognitive neuroscience of the cerebellum, including the syndrome that bears his name.
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Larger Study Confirms Loneliness as a Preclinical Symptom of Alzheimer's Disease
Researchers previously reported that in cognitively normal older adults, loneliness scores were associated with greater cortical deposition of amyloid-β. These findings have now been confirmed in a larger study that also involved imaging of tau.
Learn more about the MassGeneral Institute for Neurodegenerative Disease
Neurodegenerative Disease contributors
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Lunasin Does Not Slow ALS Progression
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Joel A. Salinas, MD, MSc, MBA
Chief, McCance Brain Health Unit
Recent Article
Social Relationships May Influence Stroke and Dementia Risk
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Jonathan Rosand, MD
Co-Director, Henry and Allison McCance Center for Brain Health, Chief, Division of Neurocritical Care and Emergency Neurology, Medical Director, Neuroscience Intensive Care Unit
Recent Article
The Impact of Trauma on Caregivers of ICU Patients
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Yakeel T. Quiroz-Gaviria, PhD
Co-Director, MGH Multicultural Neuropsychology Program (MUNDOS)
Recent Article
Research Advances from Mass General Neurology
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
