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Featured
Advancements in the Treatment of Neurodegenerative Disease
In this video, Ghazaleh Sadri-Vakili, PhD, director of the NeuroEpigenetics Laboratory and the MassGeneral Institute of Neurodegenerative Disease, discusses her genetic research, specifically concerning neurodegenerative diseases like ALS and X-linked dystonia parkinsonism.
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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Featured
Identifying New Potential Therapeutic Targets for ALS FTD
Transcripts of repeat expansions in the C90RF72 gene undergo a repeat-associated non-AUG (RAN) translation pathway that generates multiple aberrant proteins. Researchers at Mass General Hospital identified new potential therapeutic targets for ALS FTD.
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Amyloid Beta and Tau Synergize to Impair Neural Circuits in Alzheimer's Disease
In living transgenic mice, the two major proteins involved in Alzheimer's disease, amyloid beta and tau, synergize to impair neural circuits—calling into question the pertinence of therapies that target one protein or the other.
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Tau Damages Neurons in Alzheimer's Disease by Disrupting Molecular Transport
Neurologists at Massachusetts General Hospital have determined that tau fibril formation, one of the pathological hallmarks of Alzheimer's disease, disrupts molecular transport in neurons—suggesting a potential new therapeutic strategy.
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Using Stem Cells to Treat Movement Disorders
In this video, JeffreySchweitzer, MD, PhD, discusses his research using stem cell technology to restore normal function in patients with movement disorders. He believes this technology may be able to improve outcomes for patients with tremor, Parkinson's disease and dystonia.
Learn more about the MassGeneral Institute for Neurodegenerative Disease
Neurodegenerative Disease contributors
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Research Advances from Mass General Neurology
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Joel A. Salinas, MD, MSc, MBA
Chief, McCance Brain Health Unit
Recent Article
Social Relationships May Influence Stroke and Dementia Risk
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Jonathan Rosand, MD
Co-Director, Henry and Allison McCance Center for Brain Health, Chief, Division of Neurocritical Care and Emergency Neurology, Medical Director, Neuroscience Intensive Care Unit
Recent Article
Research Advances from Mass General Neurology
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Yakeel T. Quiroz-Gaviria, PhD
Co-Director, MGH Multicultural Neuropsychology Program (MUNDOS)
Recent Article
Research Advances from Mass General Neurology
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
