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Featured
Advancements in the Treatment of Neurodegenerative Disease
In this video, Ghazaleh Sadri-Vakili, PhD, director of the NeuroEpigenetics Laboratory and the MassGeneral Institute of Neurodegenerative Disease, discusses her genetic research, specifically concerning neurodegenerative diseases like ALS and X-linked dystonia parkinsonism.
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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Featured
Identifying New Potential Therapeutic Targets for ALS FTD
Transcripts of repeat expansions in the C90RF72 gene undergo a repeat-associated non-AUG (RAN) translation pathway that generates multiple aberrant proteins. Researchers at Mass General Hospital identified new potential therapeutic targets for ALS FTD.
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Brain Infection with Herpes Virus May Accelerate Progression of Alzheimer's Disease
Laboratory studies at Mass General suggest that active herpes infections in the brain may accelerate amyloid deposition and the progression of Alzheimer's disease.
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Alzheimer’s in a Dish Model Replicates Pathology, Including Inflammation
A Mass General research team has built on their previous development of a system that fully replicates the pathology behind Alzheimer’s disease to now include inflammation
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Social Relationships May Influence Stroke and Dementia Risk
Two very different risk factors, social isolation and low levels of brain-derived neurotrophic factor, are associated with increased risk of stroke and dementia. Mass General researchers investigated whether social relationships reduce stroke and dementia risk through the BDNF pathway.
Learn more about the MassGeneral Institute for Neurodegenerative Disease
Neurodegenerative Disease contributors
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Advancements in the Treatment of Neurodegenerative Disease -
Joel A. Salinas, MD, MSc, MBA
Chief, McCance Brain Health Unit
Recent Article
Social Relationships May Influence Stroke and Dementia Risk
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Jonathan Rosand, MD
Co-Director, Henry and Allison McCance Center for Brain Health, Chief, Division of Neurocritical Care and Emergency Neurology, Medical Director, Neuroscience Intensive Care Unit
Recent Article
Social Relationships May Influence Stroke and Dementia Risk
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Yakeel T. Quiroz-Gaviria, PhD
Co-Director, MGH Multicultural Neuropsychology Program (MUNDOS)
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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