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Featured
Cromolyn Sodium Provides Neuroprotection in Animal Model of ALS
Building on similar research in Alzheimer's disease, researchers at Massachusetts General Hospital demonstrated that treatment with cromolyn sodium delayed disease onset and was neuroprotective in a mouse model of amyotrophic lateral sclerosis by decreasing the inflammatory response.
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Featured
Case of Resistance to Autosomal Dominant Alzheimer's Disease Suggests New Direction for Treatment
A woman with autosomal dominant Alzheimer's disease had very late onset of mild cognitive impairment, apparently because she was homozygous for the APOE3 Christchurch mutation.
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Featured
Patterns of Neural Network Degradation Differ in Alzheimer's Disease and Normal Aging
Functional MRI may someday be able to distinguish the neurodegenerative changes related to early Alzheimer's disease from those of normal aging.
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Review: Understanding Neuroimaging–Genetic Intersections in the Human Brain
Ibai Diez, PhD, and Jorge Sepulcre, PhD, DMSc, MD, of the Gordon Center for Medical Imaging, explain how neuroimaging findings are being combined with genetic data—research that might lead to disease-modifying therapies for neurodegenerative diseases.
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How Amyloid-beta Forms Suggests New Strategies for Preventing, Treating Alzheimer's Disease
In a study with major implications for drug development in Alzheimer's disease, Raja Bhattacharyya, PhD, and Rudolph E. Tanzi, PhD, of the McCance Center for Brain Health, and colleagues have determined how neurotoxic amyloid-β is generated in axons and how its production can be reduced.
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Novel Genetic Loci Linked to Cognitive Decline in Parkinson's Disease
As part of an international consortium, Massachusetts General Hospital neurologists helped identify three genetic loci, and confirm two others, that influence time to progression to dementia in Parkinson's disease, and devised a polygenic score that predicts which PD patients are likely to rapidly develop dementia.
Neurodegenerative Disease Contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
The Future of Neurosurgery and Neuroscience at Mass General: Q&A With Bob S. Carter, MD, PhD
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Cromolyn Sodium Provides Neuroprotection in Animal Model of ALS
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Jeffrey S. Schweitzer, MD, PhD
Neurosurgeon
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Joel A. Salinas, MD, MSc, MBA
Chief, McCance Brain Health Unit
Recent Article
MicroRNA From Whole Blood May Be Stroke Biomarker, Therapeutic Target
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Jonathan Rosand, MD
Co-Director, Henry and Allison McCance Center for Brain Health, Chief, Division of Neurocritical Care and Emergency Neurology, Medical Director, Neuroscience Intensive Care Unit
Recent Article
Pilot Trial: Resiliency Intervention Feasible for Survivors of Critical Neurologic Illness, Family Caregivers
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Todd M. Herrington, MD, PhD
Director, Deep Brain Stimulation Program, Massachusetts General Hospital
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Yakeel T. Quiroz-Gaviria, PhD
Associate Professor, Harvard Medical School, Director, Familial Dementia Neuroimaging Lab, Director, Multicultural Alzheimer's Prevention Program, Massachusetts General Hospital, Paul B. and Sandra M. Edgerley MGH Research Scholar 2020-2025
Recent Article
Retinal Imaging Detects Biomarkers of Familial Alzheimer's Disease Years Before Symptoms
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
