Specialty Rheumatology, Allergy and Immunology
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Featured
Study Seeks FDA-approved Therapy for IgG4-related Disease
Massachusetts General Hospital is conducting an NIH-funded clinical trial exploring elotuzumab as a treatment for IgG4-related disease.
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Featured
Severe Allergic Reactions Are Rare with COVID-19 mRNA Vaccines
A prospective study of employee mRNA COVID-19 vaccination at Mass General Brigham linked self-reported history of high-risk allergy to increased risk of self-reported allergic reactions, but only 0.3% of employees had severe reactions and the vast majority completed the two-dose series.
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Novel Schema Classifies Allergy-related Safety Events in Healthcare Settings
Researchers at Massachusetts General Hospital analyzed 299,031 safety reports and identified 744 allergy-related safety events they used to create a novel allergy safety event classification schema. With further development, it could be used to reduce patient exposure to known allergens in healthcare settings.
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Pathways Case Record: Investigating Paraneoplastic Autoimmunity: A Case of Dermatomyositis in a Patient With Rectal Adenocarcinoma
A 55-year-old woman with a history of resected rectal adenocarcinoma was admitted for progressive proximal muscle weakness and rash; she was diagnosed with inflammatory myositis overlap syndrome. The Pathways Service was consulted and investigated the potential association between autoimmune diseases and malignancies.
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Pathways Case Record: A Patient With Cirrhosis and Small Bowel Edema
A 39-year-old man presented with an acute episode of severe epigastric pain, and initial evaluation revealed extensive small bowel edema and C1 esterase inhibitor (C1-INH) deficiency. The Pathways Service team was consulted to investigate the pathophysiologic mechanism for his dramatic small bowel edema.
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Pathways Case Record: Anti-HMGCR+ Immune-mediated Necrotizing Myopathy
The Pathways Consult Service at Massachusetts General Hospital investigated the case of an 85-year-old woman who was admitted for progressive muscle weakness and fatigue over the course of a month. A muscle biopsy showed pathology consistent with immune-mediated necrotizing myopathy (IMNM).
Rheumatology, Allergy and Immunology Contributors
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Andrew D. Luster, MD, PhD
Chief of the Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Director of the Center for Immunology and Inflammatory Diseases
Recent Article
The Role of Atypical Chemoattractant Receptors in Recruiting Neutrophils into Inflamed Tissue Sites
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Hak Soo Choi, PhD
Director, Bioengineering and Nanomedicine Program, Massachusetts General Hospital, Associate Professor of Radiology, Harvard Medical School, Faculty, Dana-Farber/Harvard Cancer Center
Recent Article
Tissue-Specific Contrast Agents for Optical Fluorescence to Evaluate Rheumatoid Arthritis -
Hyon Choi, MD
Program Director, Clinical Epidemiology Program, Massachusetts General Hospital, Clinical Rheumatologist, Department of Medicine
Recent Article
Allopurinol Treatment-to-Target Does Not Increase Mortality Risk in Patients With Comorbid Gout, CKD
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John H. Stone, MD, MPH
Director, Clinical Rheumatology, Massachusetts General Hospital, Edward A. Fox Chair in Medicine at Mass General
Recent Article
Initiate Weekly Tocilizumab As Soon As Possible in Giant Cell Arteritis
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Kimberly G. Blumenthal, MD, MSc
Quality and Safety Officer for Allergy, Massachusetts General Hospital, Co-Director, Clinical Epidemiology Program, Division of Rheumatology, Allergy and Immunology
Recent Article
Novel Schema Classifies Allergy-related Safety Events in Healthcare Settings
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Wayne G. Shreffler, MD, PhD
Chief, Pediatric Allergy & Immunology, Director, Food Allergy Center, Principal Investigator, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital
Recent Article
Key Allergic Mediators of Eosinophilic Esophagitis Identified -
Yuqing Zhang, DSc
Director of Epidemiological and Biostatistical Methods, Rheumatology Unit, Massachusetts General Hospital, Professor in Residence in Medicine, Harvard Medical School
Recent Article
Allopurinol Treatment-to-Target Does Not Increase Mortality Risk in Patients With Comorbid Gout, CKD -
Zachary S. Wallace, MD, MSc
Physician, Rheumatology Unit, Massachusetts General Hospital
Recent Article
Anti-CD20 Monoclonal Antibody Therapy for Immune-mediated Diseases Increases Risk of Death from COVID-19
Rheumatology, Allergy and Immunology
The Division of Rheumatology, Allergy and Immunology at Massachusetts General Hospital provides leading-edge treatment and transformative care to patients with rheumatic disease and autoimmune conditions.