Specialty Rheumatology, Allergy and Immunology
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Featured
Study Seeks FDA-approved Therapy for IgG4-related Disease
Massachusetts General Hospital is conducting an NIH-funded clinical trial exploring elotuzumab as a treatment for IgG4-related disease.
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Featured
Severe Allergic Reactions Are Rare with COVID-19 mRNA Vaccines
A prospective study of employee mRNA COVID-19 vaccination at Mass General Brigham linked self-reported history of high-risk allergy to increased risk of self-reported allergic reactions, but only 0.3% of employees had severe reactions and the vast majority completed the two-dose series.
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Illness-related Uncertainty Correlates With Mental Health in Patients With Systemic Autoimmune Diseases
Zachary S. Wallace, MD, MSc, Daniel L. Hall, PhD, and colleagues found associations between illness-related uncertainty and psychologic health in patients with systemic autoimmune rheumatic diseases, and the measures varied according to type of disease.
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Higher Hydroxychloroquine Dose Progressively Increases Incidence of Retinopathy
April M. Jorge, MD, Hyon K. Choi, MD, Yuqing Zhang, ScD, and colleagues conducted a large "real-world" study of the incidence of hydroxychloroquine retinopathy under contemporary dosing and surveillance standards, finding a dose-related risk of 8.6% after 15 years. 90% of cases were mild or moderate.
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Cytotoxic Immune Responses May Explain Microvasculature Damage in Post-antibiotic Lyme Arthritis
Allen C. Steere, MD, and colleagues propose that CD8+ T cell–mediated cytotoxicity, CD4+ T cell help, autoantibodies to vascular antigens, and complement deposition may each have a role in microvasculature damage in post-antibiotic Lyme arthritis.
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Efficient Early Immune Control of COVID-19 Predicts Favorable Long-term Adaptive Immunity
In blood samples from patients who recovered from the first wave of SARS-CoV-2 infection, Massachusetts General Hospital researchers found some CD4+ T cell subsets were more common with milder disease. This response persisted for several months, potentially giving the immune system an advantage for subsequent exposure.
Rheumatology, Allergy and Immunology Contributors
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Andrew D. Luster, MD, PhD
Chief of the Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Director of the Center for Immunology and Inflammatory Diseases
Recent Article
Efficient Early Immune Control of COVID-19 Predicts Favorable Long-term Adaptive Immunity
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Hak Soo Choi, PhD
Director, Bioengineering and Nanomedicine Program, Massachusetts General Hospital, Associate Professor of Radiology, Harvard Medical School, Faculty, Dana-Farber/Harvard Cancer Center
Recent Article
Tissue-Specific Contrast Agents for Optical Fluorescence to Evaluate Rheumatoid Arthritis -
Hyon Choi, MD
Program Director, Clinical Epidemiology Program, Division of Rheumatology, Allergy and Immunology, Clinical Rheumatologist, Department of Medicine, Massachusetts General Hospital, Professor of Medicine, Harvard Medical School
Recent Article
Higher Hydroxychloroquine Dose Progressively Increases Incidence of Retinopathy
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John H. Stone, MD, MPH
Director, Clinical Rheumatology, Massachusetts General Hospital, Edward A. Fox Chair in Medicine at Mass General
Recent Article
Advances in Rheumatology Course: Q&A With John Stone, MD, MPH
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Kimberly G. Blumenthal, MD, MSc
Quality and Safety Officer for Allergy, Co-Director, Clinical Epidemiology Program, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Assistant Professor of Medicine, Harvard Medical School
Recent Article
Novel Schema Classifies Allergy-related Safety Events in Healthcare Settings
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Wayne G. Shreffler, MD, PhD
Chief, Pediatric Allergy & Immunology, Director, Food Allergy Center, Principal Investigator, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital
Recent Article
Key Allergic Mediators of Eosinophilic Esophagitis Identified -
Yuqing Zhang, ScD
Director of Epidemiological and Biostatistical Methods, Rheumatology Unit, Massachusetts General Hospital, Professor in Residence of Medicine, Harvard Medical School
Recent Article
Higher Hydroxychloroquine Dose Progressively Increases Incidence of Retinopathy -
Zachary S. Wallace, MD, MSc
Physician, Rheumatology Unit, Massachusetts General Hospital, Assistant Professor of Medicine, Harvard Medical School
Recent Article
Illness-related Uncertainty Correlates With Mental Health in Patients With Systemic Autoimmune Diseases
Rheumatology, Allergy and Immunology
The Division of Rheumatology, Allergy and Immunology at Massachusetts General Hospital provides leading-edge treatment and transformative care to patients with rheumatic disease and autoimmune conditions.