Posts by Yuqing Zhang, ScD
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Higher Hydroxychloroquine Dose Progressively Increases Incidence of Retinopathy
April M. Jorge, MD, Hyon K. Choi, MD, Yuqing Zhang, ScD, and colleagues conducted a large "real-world" study of the incidence of hydroxychloroquine retinopathy under contemporary dosing and surveillance standards, finding a dose-related risk of 8.6% after 15 years. 90% of cases were mild or moderate.
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Allopurinol Treatment-to-Target Does Not Increase Mortality Risk in Patients With Comorbid Gout, CKD
Yuqing Zhang, DSc, Hyon K. Choi, MD, and colleagues found that allopurinol use does not increase the five-year risk of death in patients with gout and concurrent chronic kidney disease, either overall or when analyses were limited to patients who achieved the target serum urate level or required dose escalation.
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Rheumatoid Arthritis Tied to Increased Risk of Contracting COVID-19
Yuqing Zhang, DSc, and colleagues in the Division of Rheumatology, Allergy and Immunology at Massachusetts General Hospital found the incidence of COVID-19 is higher among patients with rheumatoid arthritis than in the general population, regardless of medication use and multiple other potential confounders.
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Osteoarthritis of Knee or Hip Increases Risk of Venous Thromboembolism
The first study of its kind shows that patients with knee or hip osteoarthritis are at high risk of developing venous thromboembolism, even if they don't undergo joint arthroplasty.
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High Prevalence of Patellofemoral Osteoarthritis Detected in China
The first compartment-specific study of patellofemoral osteoarthritis in China showed a high prevalence overall and a much higher rate of lateral disease than medial disease.
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Cardiovascular Safety of Tramadol Not Assured for Osteoarthritis Patients
In a large population-based study of patients with osteoarthritis, the risk of myocardial infarction with tramadol was higher or comparable to that with NSAIDs and comparable to that with codeine.
Biography
Dr. Zhang is the Director of Epidemiological and Biostatistical Methods in Rheumatology at Massachusetts General Hospital and a Professor in Residence of Medicine at Harvard Medical School. He is a senior epidemiologist with expertise in study design and statistical analysis, and has mentored both MD and PhD trainees and junior faculty for over 30 years.
Over the past several years he has applied causal inference theory to clarify the paradoxical phenomenon in observational studies of risk factors for progression and sequelae of musculoskeletal diseases and developed a novel approach of online case-crossover study to examine triggers for disease flare.
Rheumatology, Allergy and Immunology
The Division of Rheumatology, Allergy and Immunology at Massachusetts General Hospital provides leading-edge treatment and transformative care to patients with rheumatic disease and autoimmune conditions.