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Featured
Sex-specific Genetic Effects Across Neuropsychiatric and Behavioral Traits Identified for the First Time
Jill M. Goldstein, PhD, and Jordan W. Smoller, MD, ScD, of the Department of Psychiatry, and colleagues have reported the first modest evidence of sex-dependent autosomal genetic effects across neuropsychiatric and behavioral traits.
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Featured
Longitudinal Data in Electronic Health Records Can Be Used to Predict Risk of Suicide
Previous research has shown that diagnostic codes routinely collected in electronic health records can help predict domestic abuse an average of two years in advance. Could EHR systems also be used to predict suicidal behavior?
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Level of Engagement With Smartphone-delivered Psychotherapy Not Linked to Treatment Response
Hilary Weingarden, PhD, Sabine Willhelm, PhD, and colleagues have determined individuals with body dysmorphic disorder who spend more total time or sessions on smartphone-delivered cognitive–behavioral therapy don't necessarily improve more than those who were lighter users.
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Performance on Test of Semantic Abilities Linked to Early Alzheimer's Disease Brain Pathology
In not-yet-demented carriers of a mutation that inevitably causes Alzheimer's disease (AD), Massachusetts General Hospital researchers found a significant link between "clustering" on a category fluency test and brain levels of amyloid and tau, suggesting cognitive testing might someday detect early or preclinical AD.
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Genetic Patterning for Psychopathology Is Distinct in Children and Adults
Dylan E. Hughes, Joshua L. Roffman, MD, MMSc and colleagues found that psychopathology in children is most strongly related to a neurodevelopmental polygenic score comprising overlapping variants across ADHD, autism spectrum disorder, MDD and Tourette's, rather than to disease-specific polygenic scores as in adults.
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Youth Team Sports Participation Associates With Reduced Psychopathology Via Interaction With Biological Risk Factors
Keiko Kunitoki, MD, Joshua L. Roffman, MD, MMSc, and colleagues have linked participation in team sports more strongly to childhood mental health, compared with previous reports, by identifying polygenic risk and subcortical volume as potential intermediate biological mechanisms.
Psychiatry Contributors
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David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program
Recent Article
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
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Eve Valera, PhD
Researcher, Athinoula A. Martinos Center for Biomedical Imaging
Recent Article
Q&A: Dr. Eve Valera on Intimate Partner Violence and Brain Injury
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Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Cannabis Use Disorder Can Develop Soon After a Medical Marijuana Card Is Obtained
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Jordan W. Smoller, MD, ScD
Associate Chief for Research, Department of Psychiatry, Massachusetts General Hospital, Director, Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health
Recent Article
Psychiatric Disorders Not Associated With Incidental Findings in Medically Actionable Genes
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Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
Diminished Frontal Pole Size, Functional Connectivity Linked to Elevated Suicide Risk in Young Adults
Neuroscience Care at Mass General
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