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Featured
Sex-specific Genetic Effects Across Neuropsychiatric and Behavioral Traits Identified for the First Time
Jill M. Goldstein, PhD, and Jordan W. Smoller, MD, ScD, of the Department of Psychiatry, and colleagues have reported the first modest evidence of sex-dependent autosomal genetic effects across neuropsychiatric and behavioral traits.
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Featured
Longitudinal Data in Electronic Health Records Can Be Used to Predict Risk of Suicide
Previous research has shown that diagnostic codes routinely collected in electronic health records can help predict domestic abuse an average of two years in advance. Could EHR systems also be used to predict suicidal behavior?
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Propensity Score Weighting Accounts Well for Placebo Response in Two Trials of Medical Therapy for MDD
Maurizio Fava, MD, and colleagues previously developed an AI approach to account for the propensity to respond to placebo in randomized, controlled trials of drugs for major depressive disorder (MDD), and they show the method more accurately interprets the results of trials complicated by the placebo response.
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Insights on Substance Use Disorder Treatment and Stigma Reduction: Q&A With Sarah Wakeman, MD
Sarah E. Wakeman, MD, specializes in Substance Use Disorder (SUD) treatment and is dedicated to advancing care through integration, education, and policy advocacy. She discusses the evolving understanding of SUD, the importance of reducing stigma, and innovative approaches to integrating addiction care.
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Brain Pathology Adds to Evidence of Link Between Social Activity and Preserved Cognition in Older Adults
Heidi I. L. Jacobs, PhD, and colleagues determined the greater density of tau tangles in the locus coeruleus may degrade cognition and social function independently of Alzheimer's disease pathology and before the onset of cognitive impairment. And that the amount of social activity can partially explain this.
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Review: Cognitive Issues in Patients With IDH-mutant Gliomas
Michael W. Parsons, PhD, and David S. Sabsevitz, PhD, recently shared their expertise about how and why to integrate neuropsychological assessment into the preoperative care and long-term follow-up of patients with IDH-mutant glioma.
Psychiatry Contributors
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David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Joyce R. Tedlow Professor of Psychiatry, Harvard Medical School
Recent Article
Heated Yoga Linked to Reduction of Moderate to Severe Depressive Symptoms in Randomized Controlled Trial -
Eve Valera, PhD
Researcher, Athinoula A. Martinos Center for Biomedical Imaging
Recent Article
Q&A: Dr. Eve Valera on Intimate Partner Violence and Brain Injury -
Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Pain Catastrophizing Is Associated With Reduced Neural Response to Monetary Reward -
Jordan W. Smoller, MD, ScD
Associate Chief for Research, Department of Psychiatry, Massachusetts General Hospital, Director, Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health
Recent Article
Psychiatric Disorders Not Associated With Incidental Findings in Medically Actionable Genes -
Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
Propensity Score Weighting Accounts Well for Placebo Response in Two Trials of Medical Therapy for MDD