Specialty Ophthalmology
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Featured
Researchers Find Potential Path to a Broadly Protective COVID-19 Vaccine Using T cells
Gaurav Gaiha, MD, DPhil, and Elizabeth Rossin, MD, PhD, use structure-based network analysis to confirm predictions about the potential for a T cell vaccine that provides protection against existing variants, such as the Delta variant, and future SARS-CoV-2 variants.
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Featured
Using Artificial Intelligence to Diagnose Glaucoma
David S. Friedman, MD, PhD, MPH, a clinician-scientist and director of the Glaucoma Service in the Department of Ophthalmology, discusses the implementation of artificial intelligence in the detection of glaucoma in screening with photographs.
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Featured
Potential Treatment Targets Identified for Age-Related Macular Degeneration
By assessing genomic–metabolomic associations in age-related macular degeneration, Deeba Husain, MD, of the Department of Ophthalmology, and colleagues have obtained additional evidence of the pathogenic role of the LIPC gene and glycerophospholipid metabolism, which may represent novel treatment targets.
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Gene Therapy Reverses Degeneration of the Retinal Pigment Epithelium in Preclinical Models
Gene therapy with Nrf2—a master transcription factor—preserves the retinal pigment epithelium in mouse models of retinitis pigmentosa, David M. Wu, MD, PhD, of the Department of Ophthalmology, and colleagues observed.
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RUNX1 Inhibition Proposed for Prevention, Treatment of Lung Injury in Severe COVID-19
Leo Am Kim, MD, PhD, and Joseph F. Arboleda-Velasquez, MD, PhD, of Mass Eye and Ear, and colleagues found that a small-molecule inhibitor of the RUNX1 transcription factor robustly ameliorates lung fibrosis in an animal model and reduces expression of host proteins critical to SARS-CoV-2 infection.
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Widefield Swept-Source OCTA Predicts Vitreous Hemorrhage in Patients with Proliferative Diabetic Retinopathy
In a prospective study, John B. Miller, MD, of the Department of Ophthalmology, and colleagues observed that widefield swept-source optical coherence tomography angiography, independent of conventional imaging, helped detect signs of impending vitreous hemorrhage in patients with proliferative diabetic retinopathy.
Ophthalmology Contributors
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Alice C. Lorch, MD, MPH
Assistant Professor of Ophthalmology, Harvard Medical School, Associate Chief for Quality for the Department of Ophthalmology, Mass Eye and Ear, Director, Harvard Ophthalmology Residency Training Program
Recent Article
Mass Eye and Ear Sets Standards of Transparency and Accountability in Ophthalmology
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Bruce Ksander, PhD
Associate Professor of Ophthalmology, Harvard Medical School, Associate Scientist, Mass Eye and Ear
Recent Article
Turning Back the Clock on Aged Eye Cells
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Janey L. Wiggs, MD, PhD
Associate Chief, Ophthalmology Clinical Research, Mass Eye and Ear, Paul Austin Chandler Professor of Ophthalmology, Harvard Medical School
Recent Article
Genetic Risk Factor for Alzheimer's Disease Linked to Reduced Glaucoma Risk
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Joan W. Miller, MD
Chief, Ophthalmology Department, Massachusetts General Hospital, Chief, Ophthalmology Department, Mass Eye and Ear, Ophthalmologist-in-Chief, Brigham and Women’s Hospital
Recent Article
Mass Eye and Ear Sets Standards of Transparency and Accountability in Ophthalmology
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Lucia Sobrin, MD, MPH
Associate Chief of Clinical Data Science and Director of the Morse Laser Center, Mass Eye and Ear, Associate Professor of Ophthalmology, Harvard Medical School, Co-Director, Ocular Immunology and Uveitis Fellowship
Recent Article
Female Hormonal Therapy Makes Only Small Contribution to Risk of Noninfectious Uveitis
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Luk Vandenberghe, PhD
Associate Professor of Ophthalmology, Harvard Medical School, Grousbeck Family Chair in Gene Therapy and Director of the Grousbeck Gene Therapy Center, Mass Eye and Ear
Recent Article
Developing a Gene-based Vaccine Candidate for COVID-19
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Meredith Gregory-Ksander, PhD
Associate Scientist, Schepens Eye Research Institute, Mass Eye and Ear, Assistant Professor of Ophthalmology, Harvard Medical School
Recent Article
Turning Back the Clock on Aged Eye Cells
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Milica Margeta, MD, PhD
Assistant Professor of Ophthalmology, Harvard Medical School, Assistant Scientist, Mass Eye and Ear
Recent Article
Genetic Risk Factor for Alzheimer's Disease Linked to Reduced Glaucoma Risk
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Tobias Elze, PhD
Assistant Professor of Ophthalmology, Harvard Medical School, Assistant Scientist, Mass Eye and Ear
Recent Article
Central Visual Field Patterns Identified by Artificial Intelligence Improve Prediction of Glaucoma Progression
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Ula V. Jurkunas, MD
Associate Professor of Ophthalmology, Harvard Medical School, Associate Scientist, Mass Eye and Ear
Mass Eye and Ear/Mass General Ophthalmology
An international center for ophthalmology treatment and research, Mass Eye and Ear/Massachusetts General Hospital is the primary teaching hospital of Harvard Medical School’s Department of Ophthalmology, and is consistently recognized as one of the nation’s top hospitals for eye care. Led by Chief and Chair Joan W. Miller, MD, the department provides seamless access to the most innovative care available anywhere in the world.
