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Featured
Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients
In this Q&A, Lorenzo Berra, MD, and Charles Hardin, MD, PhD, of Massachusetts General Hospital explain the link between acute respiratory distress syndrome (ARDS) and share insight into upcoming research on antiviral treatment approaches.
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Damage to the Alveolar Epithelial Glycocalyx Contributes to Lung Injury in ARDS
Alicia N. Rizzo, MD, PhD, Eric P. Schmidt, MD, and colleagues demonstrate alveolar epithelial glycocalyx integrity is critical to surfactant function, link shedding of this layer to the severity and duration of acute respiratory distress syndrome, and propose a rapid bedside assay that provides prognostic information.
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Prolonged Prone Ventilation Decreases COVID-19 Mortality
Research at Massachusetts General Hospital demonstrates that prolonged prone positioning during mechanical ventilation decreases COVID-19-related mortality.
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Endothelial Signaling Pathway Linked to Pulmonary Fibrosis
Research at Massachusetts General Hospital identifies a link between endothelial S1PR1 and the development of pulmonary fibrosis.
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High-dose Inhaled Nitric Oxide Safe, Effective for Non-Intubated COVID-19 Patients
Lorenzo Berra, MD, and Bijan Safaee Fakhr, MD, of the Department of Anesthesia, Critical Care and Pain Medicine, and colleagues found that high-dose inhaled nitric oxide produced a beneficial effect on the respiratory system of non-intubated hospitalized COVID-19 patients without adverse events.
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Persistent Dyspnea After COVID-19 May Have Another Cause
Corey Hardin, MD, PhD, and George A. Alba, MD, and colleagues found most patients with persistent dyspnea and exercise intolerance after COVID-19 have mild or no abnormalities on cardiopulmonary exercise testing, while severe abnormalities on cardiopulmonary exercise testing may be seen in patients with severe or critical COVID-19.
Acute Respiratory Distress Syndrome Contributors
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Charles Corey Hardin, MD, PhD
Physician, Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Assistant Professor of Medicine, Harvard Medical School, Physician Investigator, Pulmonary, Mass General Research Institute
Recent Article
Persistent Dyspnea After COVID-19 May Have Another Cause
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David M. Dudzinski, MD
Intensive Care Cardiologist, Massachusetts General Hospital, Director, Cardiac Intensive Care Unit, Associate Editor, Case Records of the MGH
Recent Article
Training for Critical Care Cardiology Through Critical Care Medicine Fellowships
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Lorenzo Berra, MD
Medical Director, Respiratory Care, Massachusetts General Hospital
Recent Article
Inhaled Nitric Oxide Improves Oxygenation in Pregnant Patients With COVID-19 Pneumonia
Pulmonary and Critical Care Medicine
The Division of Pulmonary and Critical Care Medicine at Massachusetts General Hospital provides comprehensive care for the full range of respiratory conditions and diseases.