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Featured
Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients
In this Q&A, Lorenzo Berra, MD, and Charles Hardin, MD, PhD, of Massachusetts General Hospital explain the link between acute respiratory distress syndrome (ARDS) and share insight into upcoming research on antiviral treatment approaches.
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Endothelial Signaling Pathway Linked to Pulmonary Fibrosis
Research at Massachusetts General Hospital identifies a link between endothelial S1PR1 and the development of pulmonary fibrosis.
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High-dose Inhaled Nitric Oxide Safe, Effective for Non-Intubated COVID-19 Patients
Lorenzo Berra, MD, and Bijan Safaee Fakhr, MD, of the Department of Anesthesia, Critical Care and Pain Medicine, and colleagues found that high-dose inhaled nitric oxide produced a beneficial effect on the respiratory system of non-intubated hospitalized COVID-19 patients without adverse events.
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Persistent Dyspnea After COVID-19 May Have Another Cause
Corey Hardin, MD, PhD, and George A. Alba, MD, and colleagues found most patients with persistent dyspnea and exercise intolerance after COVID-19 have mild or no abnormalities on cardiopulmonary exercise testing, while severe abnormalities on cardiopulmonary exercise testing may be seen in patients with severe or critical COVID-19.
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Case Series: ECMO for Myositis-Associated Rapidly Progressive Interstitial Lung Disease
Based on the largest case series to date, Massachusetts General Hospital physicians recommend continued consideration of extra-corporeal membrane oxygenation as a bridge to recovery or transplant in patients with confirmed or suspected myositis-associated rapidly progressive interstitial lung disease.
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Biological Insights into ARDS May Improve Treatment of COVID-19
By integrating genomic and transcriptomic data, David C. Christiani, MD, MPH, of the Pulmonary and Critical Care Unit, and colleagues gleaned information about the pathogenesis of acute respiratory distress syndrome (ARDS) and potential genetic targets for therapies, including therapies for COVID-19–related ARDS.
Acute Respiratory Distress Syndrome Contributors
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Charles Corey Hardin, MD, PhD
Physician, Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Assistant Professor of Medicine, Harvard Medical School, Physician Investigator, Pulmonary, Mass General Research Institute
Recent Article
Persistent Dyspnea After COVID-19 May Have Another Cause -
David M. Dudzinski, MD
Intensive Care Cardiologist, Massachusetts General Hospital, Director, Cardiac Intensive Care Unit, Associate Editor, Case Records of the MGH
Recent Article
Review: Evidence-Based Management of the Critically Ill Adult with COVID-19 -
Lorenzo Berra, MD
Medical Director, Respiratory Care, Massachusetts General Hospital
Recent Article
High-dose Inhaled Nitric Oxide Safe, Effective for Non-Intubated COVID-19 Patients