Specialty Neuroscience
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Featured
New Targeted Glioma Therapy Could Suppress Tumor Growth
Mass General has developed a genotype-targeted therapy for glioma, designed to be given at the tumor site during surgery, and an accompanying rapid diagnostic.
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Genome-wide Association Study Confirms PTSD Is in Part Genetically Determined
A consortium of psychiatry researchers from Massachusetts General Hospital has provided the first molecular genetic evidence of PTSD heritability.
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Amyloid Beta and Tau Synergize to Impair Neural Circuits in Alzheimer's Disease
In living transgenic mice, the two major proteins involved in Alzheimer's disease, amyloid beta and tau, synergize to impair neural circuits—calling into question the pertinence of therapies that target one protein or the other.
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Third-Generation CAR T-cell Therapy for Glioblastoma Is Effective in Animal Model
A new chimeric antigen receptor T-cell strategy for glioblastoma, developed at Massachusetts General Hospital and proven effective in mice, relies on co-culturing the T cells with artificial antigen-presenting cells that express co-stimulatory molecules, to boost T-cell activation and persistence.
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Leveraging Large-scale Data to Improve Psychiatric Care
Jordan W. Smoller, MD, ScD, is the director of the Psychiatric and Neurodevelopmental Genetics Unit and is the associate chief for research in the Department of Psychiatry at Mass General. In this video, he discusses his research efforts to leverage large-scale data sets that are now available from a variety of sources, including neuroscience, genomics, electronic health records, to improve the ability to diagnose, detect and treat psychiatric disorders and serious complications of those disorders.
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Meta-analysis Confirms That Tourette's Syndrome Is a Polygenic Disorder
In a meta-analysis of multiple genetic studies of Tourette's syndrome (TS), researchers found that TS results from variants in hundreds of genes working together and more variants means a more severe form of TS. Through the study, they also hoped to understand which risk variants contribute to the development of TS.
Neuroscience contributors
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Aman B. Patel, MD
Director of Cerebrovascular and Endovascular Neurosurgery, Co-Director of the Neuroendovascular Program
Recent Article
Using Data to Predict Which Aneurysms May Burst
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Third-Generation CAR T-cell Therapy for Glioblastoma Is Effective in Animal Model
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Research Advances from Mass General Neurology
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Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine
Recent Article
Translation, Discovery and Collaboration in Psychiatry
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Jonathan Rosand, MD
Co-Director, Henry and Allison McCance Center for Brain Health, Chief, Division of Neurocritical Care and Emergency Neurology, Medical Director, Neuroscience Intensive Care Unit
Recent Article
Research Advances from Mass General Neurology
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Jordan W. Smoller, MD
Associate Chief for research in the Department of Psychiatry, Director of the Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health
Recent Article
Leveraging Large-scale Data to Improve Psychiatric Care
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Maurizio Fava, MD
Director, Division of Clinical Research of the MGH Research Institute, Executive Vice Chair, Department of Psychiatry, Executive Director, MGH Clinical Trials Network & Institute (CTNI), Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
Clinical Trial Suggests New Combination Drug Targeting Opioid System May Relieve Major Depression Symptoms
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Merit Ester Cudkowicz, MD, MSc
Chief, Neurology Service, Director of the Sean M. Healey & AMG Center for ALS at Mass General, Director of Neurological Clinical Research Institute and the Jilieane Dorn Professor of Neurology, Harvard Medical School
Recent Article
Healey Center Speeds ALS Research for Patient Therapies
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Rudolph E. Tanzi, PhD
Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School, Vice-Chair, Massachusetts General Hospital Neurology Department, Director, Genetics and Aging Research Unit, Massachusetts General Hospital
Recent Article
Unconventionality in Alzheimer's Research and the Pursuit of Validation
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Timothy Wilens, MD
Chief, Division of Child and Adolescent Psychiatry, Co-director, Center for Addiction Medicine, Director, Substance Abuse Services in Pediatric Psychopharmacology
Recent Article
Practice Changes to Reduce Misuse of Prescription Medications
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology
Recent Article
Triple Immunotherapy Completely Eradicates Glioma in Animal Models
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Ziv Williams, MD
Associate Professor in Neurosurgery
Recent Article
Long-Term Visual Memory Has a Role in Suppressing Learning
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
