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Featured
New Targeted Glioma Therapy Could Suppress Tumor Growth
Mass General has developed a genotype-targeted therapy for glioma, designed to be given at the tumor site during surgery, and an accompanying rapid diagnostic.
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Featured
Surviving Gliomas Through Antibodies and Vaccination
Immunotherapy for glioma is under active investigation, but tumor-associated immunosuppression is a major obstacle. A Mass General team studied an investigational monoclonal antibody in mice with glioma, alone and in combination with tumor cell vaccination.
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Featured
How Liquid Biopsy Could Improve Brain Tumor Treatment and Diagnoses
Mass General doctors are developing a liquid biopsy for brain tumors to reduce the need for invasive tissue biopsies.
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Noninvasive Techniques in Brain Tumor Treatment
Noninvasive techniques are useful for indicating whether or not a drug is delivered to the tumor and effective. In this video, Bakhos Tannous, PhD, discusses research in molecular imaging that investigates how secreted luciferase could act as a probe to indicate the drug's efficacy.
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Noninvasive Measurement of Brain Activity Might Improve Prognostication, Treatment of Glioma
Working with colleagues in the Netherlands, a neuroscientist at Massachusetts General Hospital has demonstrated for the first time that noninvasive measurement of brain activity with magnetoencephalography can predict progression-free survival in patients with glioma and might even lead to new therapeutic strategies.
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Third-Generation CAR T-cell Therapy for Glioblastoma Is Effective in Animal Model
A new chimeric antigen receptor T-cell strategy for glioblastoma, developed at Massachusetts General Hospital and proven effective in mice, relies on co-culturing the T cells with artificial antigen-presenting cells that express co-stimulatory molecules, to boost T-cell activation and persistence.
Brain Tumor contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Third-Generation CAR T-cell Therapy for Glioblastoma Is Effective in Animal Model
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Brian V. Nahed, MD, MSc
Neurosurgical Oncology / Brain Tumor Surgeon / Mass General Brain Tumor Center, Neurosurgical Spinal Disorders, Associate Professor, Harvard Medical School
Associate Director Mass General Neurosurgery ProgramRecent Article
The Mass General Neurosurgery Mission
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology
Recent Article
Triple Immunotherapy Completely Eradicates Glioma in Animal Models
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
