TopicBrain Tumor

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New Targeted Glioma Therapy Could Suppress Tumor Growth

Mass General has developed a genotype-targeted therapy for glioma, designed to be given at the tumor site during surgery, and an accompanying rapid diagnostic.

Brain Tumor, Neuroscience, Neurosurgery

Article August 9, 2018

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Surviving Gliomas Through Antibodies and Vaccination

Immunotherapy for glioma is under active investigation, but tumor-associated immunosuppression is a major obstacle. A Mass General team studied an investigational monoclonal antibody in mice with glioma, alone and in combination with tumor cell vaccination.

Brain Tumor, Neuroscience, Neurosurgery

Journal June 20, 2018

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How Liquid Biopsy Could Improve Brain Tumor Treatment and Diagnoses

Mass General doctors are developing a liquid biopsy for brain tumors to reduce the need for invasive tissue biopsies.

Brain Tumor, Neuroscience, Neurosurgery

Article May 19, 2018

Triple Immunotherapy Completely Eradicates Glioma in Animal Models

Researchers at Massachusetts General Hospital found that combining a PD-1 inhibitor with whole tumor cell vaccination and agonist anti-OX40 antibody in a glioma animal model cured all animals and resulted in long-term survival—even after glioma rechallenge.

Brain Tumor, Neuroscience, Neurosurgery

Journal April 19, 2019

New Therapies for Brain Tumors

Brain tumors are difficult to treat because the brain has natural barriers that can resist therapy. In this video, Bakhos Tannous, PhD, discusses his research on the effects of using stem-like cells to treat brain tumors in hopes to deliver more effective treatment.

Brain Tumor, Neurology, Neuroscience

Video April 2, 2019

New Research and Treatment Options for IDH1 Mutant Tumors

In this video, Bob Carter, MD, PhD, describes the work of Daniel Cahill, MD, PhD, who is leading research on IDH1 mutant brain tumors.

Brain Tumor, Neuroscience, Neurosurgery

Video March 29, 2019