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Featured
New Targeted Glioma Therapy Could Suppress Tumor Growth
Mass General has developed a genotype-targeted therapy for glioma, designed to be given at the tumor site during surgery, and an accompanying rapid diagnostic.
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Featured
Surviving Gliomas Through Antibodies and Vaccination
Immunotherapy for glioma is under active investigation, but tumor-associated immunosuppression is a major obstacle. A Mass General team studied an investigational monoclonal antibody in mice with glioma, alone and in combination with tumor cell vaccination.
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Featured
How Liquid Biopsy Could Improve Brain Tumor Treatment and Diagnoses
Mass General doctors are developing a liquid biopsy for brain tumors to reduce the need for invasive tissue biopsies.
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Circulating Blood Counts Predict Response, Survival in Recurrent Glioblastoma Treated with Bevacizumab
Massachusetts General Hospital researchers are the first to report that changes in eosinophil, lymphocyte and platelet counts might serve as biomarkers of clinical outcomes in patients with recurrent glioblastoma who are treated with bevacizumab.
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Novel Combination Therapy Highly Effective Against IDH-mutant Glioma
Adding a poly(ADP-ribose) glycohydrolase inhibitor to temozolomide was highly effective in glioma cell lines and an IDH-mutant xenograft mouse model.
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New Cellular "Blueprint" of Glioblastoma Explains Why It's So Hard to Treat
Researchers from the Massachusetts General Hospital Cancer Center find that single-cell analyses of glioblastoma have revealed multiple cellular states, and plasticity between those states, which explains why targeting one gene at a time has failed.
Brain Tumor contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Gene Fusions Detected in Plasma of Glioblastoma Patients, Suggesting New Approach to Liquid Biopsy
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Brian V. Nahed, MD, MSc
Neurosurgical Oncology / Brain Tumor Surgeon / Mass General Brain Tumor Center, Neurosurgical Spinal Disorders, Associate Professor, Harvard Medical School
Associate Director Mass General Neurosurgery ProgramRecent Article
Circulating Blood Counts Predict Response, Survival in Recurrent Glioblastoma Treated with Bevacizumab
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Daniel P. Cahill, MD, PhD
Neurosurgeon
Recent Article
Novel Combination Therapy Highly Effective Against IDH-mutant Glioma
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology
Recent Article
Endonasal Surgery Using High-Speed Drill Puts Health Care Team at Risk of COVID-19
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
