TopicBrain Tumor

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New Targeted Glioma Therapy Could Suppress Tumor Growth

Mass General has developed a genotype-targeted therapy for glioma, designed to be given at the tumor site during surgery, and an accompanying rapid diagnostic.

Brain Tumor, Neuroscience, Neurosurgery

Article August 9, 2018

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Surviving Gliomas Through Antibodies and Vaccination

Immunotherapy for glioma is under active investigation, but tumor-associated immunosuppression is a major obstacle. A Mass General team studied an investigational monoclonal antibody in mice with glioma, alone and in combination with tumor cell vaccination.

Brain Tumor, Neuroscience, Neurosurgery

Journal June 20, 2018

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How Liquid Biopsy Could Improve Brain Tumor Treatment and Diagnoses

Mass General doctors are developing a liquid biopsy for brain tumors to reduce the need for invasive tissue biopsies.

Brain Tumor, Neuroscience, Neurosurgery

Article May 19, 2018

Review: Intraoperative MRI for Pituitary Adenomas

The use of magnetic resonance imaging during transsphenoidal surgery for pituitary adenomas provides images that allow detection of residual tumor and increase the likelihood of gross total resection.

Brain Tumor, Neuroscience, Neurosurgery

Journal December 26, 2019

Combined Blockade of ATR and PARP Effective Against Glioblastoma in Mice

The combination of olaparib and an ATR inhibitor was effective against glioblastoma in mice, providing a much-needed therapeutic breakthrough for this deadly disease.

Brain Tumor, Neuroscience, Neurosurgery

Journal December 16, 2019

New Tool Measures Glioma Response to Treatment Automatically

AutoRANO, a new automated algorithm, reliably evaluates change in glioma size and volume over time according to the Response Assessment in Neuro-Oncology criteria.

Brain Tumor, Neuroscience, Neurosurgery

Journal October 1, 2019