Specialty Urology
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Featured
Pelvic Floor Muscle Training for Urinary Incontinence Treats Other Pelvic Floor Disorders
Milena Weinstein, MD, and colleagues demonstrated that among women who had fecal incontinence and/or pelvic organ prolapse and urinary incontinence (UI), use of a motion-based device to guide pelvic floor muscle training led to 2.5 times greater odds of improvement in UI symptoms and also improved the other symptoms.
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Improving Prostate MRI Screening for Genetically High-Risk Individuals
New research with roots at Mass General Brigham Cancer Institute shows that combining age-adjusted PSA thresholds with upfront MRI improves detection of clinically significant prostate cancer in genetically high-risk men—outperforming either test alone.
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How a Neoadjuvant Microdevice Could Transform Treatment of Prostate Cancer
Mass General Brigham researchers are in the early stages of developing a 3mm implantable chip that delivers micro-doses of drugs directly into prostate tumors prior to planned radical prostatectomy. Analyzing tumor response eventually could help clinicians optimize drug selection for individual patients.
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Monitoring of PSA Density Advised During Active Surveillance of Prostate Cancer
Adam S. Feldman, MD, MPH, Andrew Gusev, MD, and colleagues, are the first to show that prostate-specific antigen density retains significant prognostic value after diagnosis of prostate cancer, with values ≥0.15 ng/mL2 at any point during active surveillance nearly quadrupling the risk of biopsy grade progression.
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MRI Enhances Early Detection of Prostate Cancer in Men at High Genetic Risk
Andrew Amini, MD, Keyan Salari, MD, PhD, and team report prostate MRI is a highly sensitive modality for early detection of prostate cancer, particularly clinically significant disease. MRI-based screening resulted in greater net clinical benefit than the traditional strategy of measuring prostate-specific antigen.
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Multiparametric MRI Is Often False-Negative for Clinically Significant Prostate Cancer
Chin-Lee Wu, MD, PhD, Douglas M. Dahl, MD, and colleagues found that 15% of patients who had negative prostate multiparametric MRI (mpMRI) were diagnosed by 20-core standard template biopsy as having clinically significant prostate cancer. They recommend considering standard biopsy regardless of negative mpMRI.
Urology Contributors
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Adam S. Feldman, MD, MPH
Director, Combined Harvard Urologic Oncology Fellowship, Associate Chair for Research, Urologic Oncologist, Department of Urology, Massachusetts General Hospital, Associate Professor of Surgery, Harvard Medical School
Recent Article
Monitoring of PSA Density Advised During Active Surveillance of Prostate Cancer
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Ajay Nehra, MBBS
Director of Men's Health and Male Reconstructive Surgery, Senior Urologic Surgeon
Recent Article
Establishing Guidelines for Peyronie's Disease
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Brian H. Eisner, MD
Co-Director, Kidney Stone Program, Massachusetts General Hospital, Associate Professor of Surgery, Harvard Medical School
Recent Article
Pharmacologic Management of Ureteral Stent–related Symptoms Should Be Personalized
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Dianne E. Sacco, MD
Co-Director, Kidney Stone Program, Assistant Professor of Surgery, Harvard Medical School
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Douglas M. Dahl, MD
Chief, Division of Urologic Oncology, Vice-Chair, Department of Urology, Massachusetts General Hospital, Co-Director, The Claire and John Bertucci Center for Genitourinary Cancers, Mass General Brigham Cancer Institute, Associate Professor of Surgery (Urology), Harvard Medical School
Recent Article
Multiparametric MRI Is Often False-Negative for Clinically Significant Prostate Cancer
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Keyan Salari, MD, PhD
Director of Translational Research, Urologic Surgeon, Department of Urology, Massachusetts General Hospital, Director, Prostate Cancer Genetics Program, Mass General Brigham Cancer Institute, Assistant Professor of Surgery, Harvard Medical School
Recent Article
Improving Prostate MRI Screening for Genetically High-Risk Individuals
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Matthew F. Wszolek, MD
Chair of Quality and Safety, Department of Urology, Massachusetts General Hospital, Urological Oncologist, Mass General Cancer Center, Instructor in Surgery, Harvard Medical School
Recent Article
Mortality Related to Surgical Staplers and Clip Appliers Is Increasing
Urology Care at Mass General
The Department of Urology at Massachusetts General Hospital offers sophisticated, compassionate care and the most innovative treatments for patients with any type of urological condition.