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Featured
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
Mass General researchers were part of the first group to investigate whether mindfulness-based cognitive therapy might relieve depression in people with chronic pain.
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Featured
Women with Major Depression During Pregnancy Have High Rates of Recurrence During Their Child's Formative Years
Depression during pregnancy is highly likely to recur after delivery, Mass General researchers have determined. The finding implies that maternal depression is a major confounder when assessing the influence of prenatal antidepressant exposure on child neurodevelopment.
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Featured
Effective Ketamine Dosages for Treatment-resistant Depression Identified
Ketamine has long been used as a general anesthetic, but more recent research has found it to be effective in rapidly relieving depression symptoms when given at low, subanesthetic doses. New research identifies two optimal dosages.
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Clinical Trial Suggests New Combination Drug Targeting Opioid System May Relieve Major Depression Symptoms
Two clinical trials examining an investigational drug that combines buprenorphine and samidorphan to target the opioid system has shown to be safe and effective in reducing symptoms of major depression when added to standard antidepressant treatment.
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Physician Burnout and Why it is Important to Heal Outside of Work
Nasrien Ibrahim, MD, observes that physicians can lose themselves in their work and burnout. It is vital that doctors take care of themselves and engage in life outside of work so that they can be better role models for their patients.
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Calculator Predicts Which Patients with Major Depression Will Respond to Placebo
As a boon to clinicians as well as researchers, a multicenter team has identified eight easy-to-measure patient characteristics that define likely placebo responders with a high degree of accuracy.
Learn more about the Depression Clinical and Research Program
Depression contributors
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Cristina Cusin, MD
Assistant Professor in Psychiatry, Staff Psychiatrist, Depression Clinical and Research Program
Recent Article
Effective Ketamine Dosages for Treatment-resistant Depression Identified
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David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program
Recent Article
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
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Maurizio Fava, MD
Director, Division of Clinical Research of the MGH Research Institute, Executive Vice Chair, Department of Psychiatry, Executive Director, MGH Clinical Trials Network & Institute (CTNI), Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
Clinical Trial Suggests New Combination Drug Targeting Opioid System May Relieve Major Depression Symptoms
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