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Featured
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
Mass General researchers were part of the first group to investigate whether mindfulness-based cognitive therapy might relieve depression in people with chronic pain.
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Featured
Women with Major Depression During Pregnancy Have High Rates of Recurrence During Their Child's Formative Years
Depression during pregnancy is highly likely to recur after delivery, Mass General researchers have determined. The finding implies that maternal depression is a major confounder when assessing the influence of prenatal antidepressant exposure on child neurodevelopment.
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Featured
Effective Ketamine Dosages for Treatment-resistant Depression Identified
Ketamine has long been used as a general anesthetic, but more recent research has found it to be effective in rapidly relieving depression symptoms when given at low, subanesthetic doses. New research identifies two optimal dosages.
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Youth Team Sports Participation Associates With Reduced Psychopathology Via Interaction With Biological Risk Factors
Keiko Kunitoki, MD, Joshua L. Roffman, MD, MMSc, and colleagues have linked participation in team sports more strongly to childhood mental health, compared with previous reports, by identifying polygenic risk and subcortical volume as potential intermediate biological mechanisms.
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Health-related Quality of Life Among Unmarried Patients Diagnosed With Lung Cancer Worse During COVID-19 Than Before
Laura A. Petrillo, MD, Joseph A. Greer, PhD, and colleagues report the COVID-19 pandemic is not further reducing health-related quality of life (HRQOL) or exacerbating depression among patients with advanced lung cancer. Still, HRQOL is worse among unmarried patients, driven by declines in functional well-being.
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Psychiatric Disorders Not Associated With Incidental Findings in Medically Actionable Genes
Using the same approach as in a phenome-wide association study, Yen-Chen A. Feng, ScD, Jordan W. Smoller, MD, ScD, and colleagues systematically evaluated data on 15,181 individuals and did not identify any psychiatric manifestations of rare variations in medically actionable genes.
Depression Contributors
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Cristina Cusin, MD
Assistant Professor in Psychiatry, Staff Psychiatrist, Depression Clinical and Research Program
Recent Article
Q&A with Dr. Cristina Cusin: What to Know About Esketamine and Ketamine Treatment
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David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program
Recent Article
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
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Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
Diminished Frontal Pole Size, Functional Connectivity Linked to Elevated Suicide Risk in Young Adults
Neuroscience Care at Mass General
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