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Featured
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
Mass General researchers were part of the first group to investigate whether mindfulness-based cognitive therapy might relieve depression in people with chronic pain.
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Featured
Women with Major Depression During Pregnancy Have High Rates of Recurrence During Their Child's Formative Years
Depression during pregnancy is highly likely to recur after delivery, Mass General researchers have determined. The finding implies that maternal depression is a major confounder when assessing the influence of prenatal antidepressant exposure on child neurodevelopment.
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Featured
Effective Ketamine Dosages for Treatment-resistant Depression Identified
Ketamine has long been used as a general anesthetic, but more recent research has found it to be effective in rapidly relieving depression symptoms when given at low, subanesthetic doses. New research identifies two optimal dosages.
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Social Connection, Television Watching Are Modifiable Factors of Depression
Karmel W. Choi, PhD, Karestan C. Koenen, PhD, and Jordan W. Smoller, MD, ScD, of the Department of Psychiatry, and colleagues used a novel two-stage approach, an exposure-wide association scan followed by Mendelian randomization, to validate actionable targets for efforts to prevent depression.
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Genetic Susceptibility to Major Depressive Disorder Associates with Symptom Trajectories Across Childhood
Alexandre A. Lussier, PhD, and Erin C. Dunn, ScD, MPH, of the Psychiatric and Neurodevelopmental Genetics Unit, and colleagues linked a polygenic risk score to depressive phenotypes in children and adolescents, particularly youth with higher symptom levels during early adolescence.
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Psychiatric Evaluations Declined As COVID-19 Emerged in Boston
The need for quarantine and the strain on clinical resources may be reducing health systems' ability to respond to psychiatric symptoms.
Depression Contributors
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Cristina Cusin, MD
Assistant Professor in Psychiatry, Staff Psychiatrist, Depression Clinical and Research Program
Recent Article
Q&A with Dr. Cristina Cusin: What to Know About Esketamine and Ketamine Treatment
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David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program
Recent Article
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
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Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
Improvement Needed in Genetic Test–Guided Treatment of Major Depressive Disorder
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