Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Neuroscience
New Website Allows Provider Consultations for Patients With Restless Leg Syndrome
A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives.
Featured In Otolaryngology
The Toth Center: New Leadership, Novel Innovations
Scientists are working towards new, innovative approaches to faster and more accurate diagnoses, less invasive treatments, predictive medicine, and more. With new leadership and collaborations, the Toth Center at Mass Eye and Ear is making great headway for the future of head and neck cancer care.
Featured In Orthopaedics
First AI Model Developed for Diagnosis of Hip Dysplasia From Plain Radiographs
Martin Magnéli, MD, PhD, Orhun Muratoglu, PhD, and colleagues have developed two convolutional neural networks that can read plain radiographs and classify hips as dysplastic or non-dysplastic with 83% to 92% accuracy, and detect the severity of hip dysplasia based on the Crowe or Hartofilakidis classifications.
Featured In Oncology
Revolutionizing Cancer Immunotherapy for Melanoma and Beyond
Researchers at Massachusetts General Hospital won a Breakthrough Award to enhance personalized approaches to immunotherapy for metastatic melanoma.
Featured In OB/GYN
Single-Step Blastocyst Warming Validated, Saves Time Without Compromising Outcomes
Victoria S. Jiang, MD, Charles L. Bormann, PhD, and colleagues found that compared with standard blastocyst warming, a simpler protocol that removes at least 15 minutes from warming time yields similar rates of implantation, clinical pregnancy, spontaneous abortion, and live birth as well as similar birth weight.
The Latest Digestive Health Advances
Taking Aspirin Associated With Reduction in Colorectal Cancer Among High-Risk Population
Massachusetts General Hospital researchers found that regular aspirin use was associated with the greatest reduction of colorectal cancer among those at the highest risk.
Cholesterol-reducing Gut Bacteria Might Lower Heart Disease Risk
Ramnik J. Xavier, MD, PhD, Chenhao Li, PhD, Martin Stražar, PhD, and colleagues have found that cholesterol metabolism is an important property of certain gut bacteria, Oscillibacter, with potential benefits for lipid homeostasis and cardiovascular health.
Contributing Physicians
Ashwin N. Ananthakrishnan, MBBS, MPH
Director of the Crohn's and Colitis Center, Division of Gastroenterology, Mass General, Associate Professor of Medicine, Harvard Medical School
Ramnik Joseph Xavier, MD, PhD
Director, Center for the Study of Inflammatory Bowel Disease, Kurt J. Isselbacher Professor of Medicine in the Field of Gastroenterology, Harvard Medical School
Advances Specialties
Neuroscience
From Stroke Detection to Cancer Screening: AI Tools Advancing Imaging Efficiency
Mass General Brigham has developed initiatives for artificial intelligence (AI) governance and inclusion of medical expertise to address an influx of AI technology in medical imaging.
Pulmonary and Critical Care
Bionic Pancreas Improves Glycemic Control in Patients With Cystic Fibrosis-related Diabetes
Melissa Putman, MD, Jordan Sherwood, MD, and colleagues report that the insulin-only iLet bionic pancreas improved glucose control in patients with cystic fibrosis-related diabetes (CFRD) compared to usual care, without an increase in continuous glucose monitoring-measured hypoglycemia.
Urology
Multiparametric MRI Is Often False-Negative for Clinically Significant Prostate Cancer
Chin-Lee Wu, MD, PhD, Douglas M. Dahl, MD, and colleagues found that 15% of patients who had negative prostate multiparametric MRI (mpMRI) were diagnosed by 20-core standard template biopsy as having clinically significant prostate cancer. They recommend considering standard biopsy regardless of negative mpMRI.
May 9, 2025
Conference: Midlife Women's Health 2025: A Multidisciplinary Approach to Care
The Midlife Women's Health 2025 course is led by a multidisciplinary group of experts from Massachusetts General Hospital who will present on the evaluation and management of osteoporosis, gastrointestinal malignancy, stress, obesity, substance use disorder, anxiety, sexual dysfunction, breast cancer, and menopausal hormone therapy to assist clinicians in caring for their midlife patients.
Brain mechanisms of vagus nerve stimulation and stress reduction training for migraine
The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.
Multimodal profiling of stress-induced immune reprogramming in cardiovascular participants
The purpose of this research study is to learn about the effects of stress on the brain and disease of the heart and blood vessels (cardiovascular disease or CVD).
