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Featured
Brain Infection with Herpes Virus May Accelerate Progression of Alzheimer's Disease
Laboratory studies at Mass General suggest that active herpes infections in the brain may accelerate amyloid deposition and the progression of Alzheimer's disease.
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Featured
Scientists Identify Steps Needed to Address Disparities in Dementia Research and Care
According to a white paper sponsored by the Alzheimer's Association, dementia scientists must stop neglecting the need for research on underrepresented ethnic and racial groups.
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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Early Brain Changes Predict Alzheimer's Disease in Individuals at Genetic Risk
Researchers at Massachusetts General Hospital have identified some of the earliest brain changes associated with the risk to develop Alzheimer's disease by studying a kindred with the PSEN1 E280A gene mutation.
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Machine Learning Model Identifies Alzheimer's Disease–like Structural Brain Patterns in Younger, Asymptomatic Adults
Binyin Li, MD, David H. Salat, PhD, and colleagues created a machine learning classifier that detected Alzheimer's disease–like brain patterns in younger adults (40 to 59 years old) and in a cohort with mild cognitive impairment.
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Tau Pathobiology Differs Among Individuals with Alzheimer's Disease
Researchers at Massachusetts General Hospital observed differences in the kinetics of tau aggregation across brain tissue samples from individuals with sporadic Alzheimer's disease, confirming and extending the concept of patient-specific characteristics of tau in this disease.
Alzheimer's Disease Contributors
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease -
Robert Moir, PhD
Assistant Professor in Neurology, Massachusetts General Hospital
Recent Article
The Innate Immune Protection Hypothesis of Alzheimer's Disease -
Rudolph E. Tanzi, PhD
Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School, Vice-Chair, Massachusetts General Hospital Neurology Department, Co-Director of the McCance Center for Brain Health, Massachusetts General Hospital
Recent Article
How Amyloid-beta Forms Suggests New Strategies for Preventing, Treating Alzheimer's Disease -
Se Hoon Choi, PhD
Assistant Professor of Neurology, Massachusetts General Hospital
Recent Article
New Model Allows Screening of Drugs to Improve Blood–Brain Barrier Integrity in Alzheimer's Disease -
Yakeel T. Quiroz-Gaviria, PhD
Associate Professor, Harvard Medical School, Director, Familial Dementia Neuroimaging Lab, Director, Multicultural Alzheimer's Prevention Program, Massachusetts General Hospital, Paul B. and Sandra M. Edgerley MGH Research Scholar 2020-2025
Recent Article
Early Brain Changes Predict Alzheimer's Disease in Individuals at Genetic Risk