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Featured
Brain Infection with Herpes Virus May Accelerate Progression of Alzheimer's Disease
Laboratory studies at Mass General suggest that active herpes infections in the brain may accelerate amyloid deposition and the progression of Alzheimer's disease.
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Featured
Scientists Identify Steps Needed to Address Disparities in Dementia Research and Care
According to a white paper sponsored by the Alzheimer's Association, dementia scientists must stop neglecting the need for research on underrepresented ethnic and racial groups.
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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Review: Understanding Neuroimaging–Genetic Intersections in the Human Brain
Ibai Diez, PhD, and Jorge Sepulcre, PhD, DMSc, MD, of the Gordon Center for Medical Imaging, explain how neuroimaging findings are being combined with genetic data—research that might lead to disease-modifying therapies for neurodegenerative diseases.
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How Amyloid-beta Forms Suggests New Strategies for Preventing, Treating Alzheimer's Disease
In a study with major implications for drug development in Alzheimer's disease, Raja Bhattacharyya, PhD, and Rudolph E. Tanzi, PhD, of the McCance Center for Brain Health, and colleagues have determined how neurotoxic amyloid-β is generated in axons and how its production can be reduced.
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Whole-Genome Sequencing Suggests New Approaches to Drug Development for Alzheimer's Disease
Dmitry Prokopenko, PhD, and Rudolph E. Tanzi, PhD, of the Department of Neurology, and colleagues have completed the first systematic whole-genome sequencing study in Alzheimer's disease (AD), detecting 13 rare gene variants not previously associated with AD and linked to neuroplasticity and loss of synapses.
Alzheimer's Disease Contributors
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Robert Moir, PhD
Assistant Professor in Neurology, Massachusetts General Hospital
Recent Article
The Innate Immune Protection Hypothesis of Alzheimer's Disease -
Rudolph E. Tanzi, PhD
Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School, Vice-Chair, Massachusetts General Hospital Neurology Department, Co-Director of the McCance Center for Brain Health, Massachusetts General Hospital
Recent Article
How Amyloid-beta Forms Suggests New Strategies for Preventing, Treating Alzheimer's Disease
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Se Hoon Choi, PhD
Assistant Professor of Neurology, Massachusetts General Hospital
Recent Article
New Model Allows Screening of Drugs to Improve Blood–Brain Barrier Integrity in Alzheimer's Disease -
Yakeel T. Quiroz-Gaviria, PhD
Associate Professor, Harvard Medical School, Director, Familial Dementia Neuroimaging Lab, Director, Multicultural Alzheimer's Prevention Program, Massachusetts General Hospital, Paul B. and Sandra M. Edgerley MGH Research Scholar 2020-2025
Recent Article
Retinal Imaging Detects Biomarkers of Familial Alzheimer's Disease Years Before Symptoms
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
