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Featured
Brain Infection with Herpes Virus May Accelerate Progression of Alzheimer's Disease
Laboratory studies at Mass General suggest that active herpes infections in the brain may accelerate amyloid deposition and the progression of Alzheimer's disease.
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Featured
Scientists Identify Steps Needed to Address Disparities in Dementia Research and Care
According to a white paper sponsored by the Alzheimer's Association, dementia scientists must stop neglecting the need for research on underrepresented ethnic and racial groups.
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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Using Biomarkers to Predict and Prevent Alzheimer's Disease
Yakeel T. Quiroz, PhD, is the director of the Familial Dementia Neuroimaging Laboratory at Massachusetts General Hospital. For the past several years, she has been studying a Columbian family with autosomal dominant Alzheimer's disease. In this video, she discusses her research to find biomarkers that signal early brain changes associated with developing Alzheimer's Disease.
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Infectious Disease May Play a Role in Alzheimer’s disease
Over 50 million people worldwide suffer from Alzheimer’s disease, which is an incurable and fatal disease characterized pathologically by the accumulation of insoluble brain deposits called amyloid. Robert Moir, PhD, a neurobiologist at Massachusetts General Hospital, shares groundbreaking new research suggesting amyloid is actually an immune response that works to trap and neutralize invading pathogens. This discovery suggests infection may play a role in Alzheimer’s disease and is helping point the way towards urgently needed new treatment strategies.
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Unconventionality in Alzheimer's Research and the Pursuit of Validation
From the 1980s, scientists understood beta-amyloid were a toxic byproduct that, when deposited in the brain, caused Alzheimer's. However, Dr. Robert Moir followed an unconventional research path, and revealed that the development of amyloid plaques might be an immune response to microbe infections.
LEARN MORE ABOUT THE MASSGENERAL INSTITUTE FOR NEURODEGENERATIVE DISEASE
Alzheimer's Disease contributors
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Robert Moir, PhD
Assistant Professor in Neurology, Massachusetts General Hospital
Recent Article
Infectious Disease May Play a Role in Alzheimer’s disease -
Rudolph E. Tanzi, PhD
Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School, Vice-Chair, Massachusetts General Hospital Neurology Department, Director, Genetics and Aging Research Unit, Massachusetts General Hospital
Recent Article
Unconventionality in Alzheimer's Research and the Pursuit of Validation -
Se Hoon Choi, PhD
Assistant Professor of Neurology, Massachusetts General Hospital
Recent Article
Study Suggests Exercise May Boost Brain Power in Alzheimer's -
Yakeel T. Quiroz-Gaviria, PhD
Co-Director, MGH Multicultural Neuropsychology Program (MUNDOS)
Recent Article
Using Biomarkers to Predict and Prevent Alzheimer's Disease
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
