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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Featured
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
Neurologists at Mass General explore the case of a woman who endured gait disturbance, cognitive impairment and urinary incontinence for 2 years before she was diagnosed with normal-pressure hydrocephalus and successfully treated with surgical shunting.
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Featured
fMRI and EEG May Find Signals of Consciousness Earlier in Severe Traumatic Brain Injury Patients
The rate of misclassification of unconsciousness can be as high as 40%. A Mass General team studied using fMRI and EEG to better identify patients with unconsciousness in the ICU.
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Natural Language Processing Improves the Speed, Reliability of Determining Cognitive Status From Electronic Health Records
Massachusetts General Hospital researchers have devised a novel semiautomated approach to phenotyping cognitive status from the clinical notes in electronic health records and structured data. The new method improves interrater reliability and is significantly faster than manual review alone.
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Multiple Lesions Are More Frequent Than Previously Thought in Acute Ischemic Stroke
Using a large dataset of deep-profiled MR images, researchers at Massachusetts General Hospital detected multiple lesions in 50% of patients with acute ischemic stroke, usually within one vascular territory. Overall, multiple lesions were linked to higher lesion volume and greater stroke severity.
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Commentary: Sparse Brain Activity Patterns May Underlie Human Cognition
Jyrki Ahveninen, PhD, and colleagues believe sparse brain activity, where only a few neurons in a population fire at a given time, might contribute to the fingerprint patterns of activity evident in multi-voxel pattern analysis results from functional MRI—and give rise to perceptual, emotional and cognitive functions.
Neurology Contributors
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Brian L. Edlow, MD
Associate Director, Center for Neurotechnology and Neurorecovery (CNTR), Director, Laboratory for NeuroImaging of Coma and Consciousness (NICC), Director, Critical Care Research Neuroimaging
Recent Article
Ethical Implications of Neuroimaging That Detects Covert Consciousness
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Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Cannabis Use Disorder Can Develop Soon After a Medical Marijuana Card Is Obtained
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Nagagopal Venna, MD
Director, Neurology Clinic, Director, Neuro-Infectious Diseases Clinic, Director, Academic General Neurology Fellowship Program
Recent Article
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
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Yakeel T. Quiroz-Gaviria, PhD
Associate Professor, Harvard Medical School, Director, Familial Dementia Neuroimaging Lab, Director, Multicultural Alzheimer's Prevention Program, Massachusetts General Hospital, Paul B. and Sandra M. Edgerley MGH Research Scholar 2020-2025
Recent Article
MRI Feature Is Marker of Disease Progression in Preclinical Autosomal Dominant Alzheimer's Disease
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.