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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Featured
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
Neurologists at Mass General explore the case of a woman who endured gait disturbance, cognitive impairment and urinary incontinence for 2 years before she was diagnosed with normal-pressure hydrocephalus and successfully treated with surgical shunting.
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Featured
fMRI and EEG May Find Signals of Consciousness Earlier in Severe Traumatic Brain Injury Patients
The rate of misclassification of unconsciousness can be as high as 40%. A Mass General team studied using fMRI and EEG to better identify patients with unconsciousness in the ICU.
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Functional MRI Marker Can Diagnose Migraine Without Aura
Massachusetts General Hospital researchers have identified and validated a distinctive pattern of abnormal brain connections on functional MRI that discriminates between patients with and without migraine.
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Use of Prion Protein Biomarker in Prion Disease Therapy Clinical Trials
The level of prion protein in CSF is a suitable biomarker for primary prevention trials of drugs for genetic prion disease.
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Tofersen for ALS Clears Phase 1/2 Trial, Now in Phase 3
Tofersen, an investigational therapy for amyotrophic lateral sclerosis caused by SOD1 mutations, was safe and generally well tolerated over 12 weeks and lowered SOD1 protein levels in cerebrospinal fluid.
Neurology contributors
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Brian L. Edlow, MD
Associate Director, Center for Neurotechnology and Neurorecovery (CNTR), Director, Laboratory for NeuroImaging of Coma and Consciousness (NICC), Director, Critical Care Research Neuroimaging
Recent Article
Functional MRI Detects Intact Brain Network in Patient Unresponsive After COVID-19
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Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Portable Imaging Test Shows Promise for Detection of Cannabis Intoxication
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Nagagopal Venna, MD
Director, Neurology Clinic, Director, Neuro-Infectious Diseases Clinic, Director, Academic General Neurology Fellowship Program
Recent Article
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
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Yakeel T. Quiroz-Gaviria, PhD
Associate Professor, Harvard Medical School, Director, Familial Dementia Neuroimaging Lab, Massachusetts General Hospital, Director, Multicultural Alzheimer's Prevention Program-MAPP
Recent Article
Plasma Biomarker of Neurodegeneration Is Elevated in Colombian Kindred 22 Years Before Alzheimer's Symptoms
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
