Specialty Oncology
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Featured
Biomarkers of T Cell Exhaustion in Checkpoint Inhibitor Therapy
Could altering the balance between two CD8+ T cell states enhance immunotherapies? Research from the Massachusetts General Hospital Cancer Center seeks to find the answer.
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Femoral–Popliteal Bypass Graft Thrombosis May Be Sign of Occult Cancer
C.Y. Maximilian Png, MD, and Anahita Dua, MD, MS, MBA, of the Division of Vascular and Endovascular Surgery, and colleagues have determined that occult cancer doubles the risk of graft thrombosis and major adverse limb events in patients who undergo femoral–popliteal bypass.
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Cervical Cancer: Oncogene YAP1 Plays Central Role in Unconventional Carcinogenesis Mechanism
The etiology of cervical cancer is not well understood, but new data suggest human papillomavirus infection is not necessary and hyperactivation of the oncogene YAP1 alone can drive cervical carcinogenesis.
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About the Henri and Belinda Termeer Center for Targeted Therapies at the Mass General Cancer Center
Justin Gainor, MD, discusses the Henri and Belinda Termeer Center for Targeted Therapies at the Massachusetts General Hospital Cancer Center.
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Darolutamide Delays Metastasis and Death in Patients with Nonmetastatic, Castration-Resistant Prostate Cancer
Matthew R. Smith, MD, PhD, of the Massachusetts General Hospital Cancer Center, and colleagues demonstrated in a worldwide phase 3 trial in patients with nonmetastatic, castration-resistant prostate cancer that darolutamide reduced the risk of metastasis or death from any cause by 59%.
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Editorial: MRI Promising for Prostate Cancer Screening in the Asymptomatic General Population
Commenting on a multicenter, prospective U.K. study, Susanna I. Lee, MD, PhD, and Aileen O'Shea, MBBCh, BAO, of the Department of Radiology, say it's now apparent that biparametric MRI is a promising method of community-based prostate cancer screening.
Oncology contributors
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Andrew T. Chan, MD, MPH
Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
More Frequent Bowel Movements Tied to Higher Risk of Diverticulitis
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David M. Langenau, PhD
Associate Professor of Pathology, Harvard Medical School, Associate Chair for Research, Department of Pathology, Massachusetts General Hospital
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J. Keith Joung, MD, PhD
Professor of Pathology, Harvard Medical School, Center for Cancer Research, Desmond and Ann Heathwood MGH Research Scholar
Recent Article
CRISPR Base Editors Can Induce Wide-Ranging Off-Target Edits in RNA
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Joseph H. Schwab, MD
Chief, Orthopaedic Spine Surgery, Director, Spine Oncology & Co-Director, Stephen L. Harris Chordoma Center, Associate Professor of Orthopedic Surgery, Harvard Medical School
Recent Article
Novel Technique Reconstructs Lumbar Spine After Spondylectomy of Malignant Tumor
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Keith T. Flaherty, MD
Director of Clinical Research, Mass General Cancer Center, Professor of Medicine, Harvard Medical School
Recent Article
Medical Grand Rounds: Advancing New Therapies for COVID-19: Antiviral, Immunomodulation and Beyond
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Marcela G. del Carmen, MD
Chief Medical Officer, Massachusetts General Physicians Organization, Gynecologic Oncologist, Center for Gynecologic Oncology
Recent Article
How Research Has Impacted Care for Cervical Cancer video
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Marcela V. Maus, MD, PhD
Director, Cellular Immunotherapy Program, Mass General Cancer Center, Assistant Professor of Medicine, Harvard Medical School
Recent Article
CAR T-cell Therapy Feasible for Active Secondary CNS Lymphoma -
Nir Hacohen, PhD
Director, MGH Center for Cancer Immunology
Center for Cancer Research , Professor of Medicine, Harvard Medical School, Senior Member, Broad InstituteRecent Article
MGH Research Scholars Respond to COVID-19
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Raul Mostoslavsky, MD, PhD
Laurel Schwartz Professor of Medicine in the Field of Oncology, Mass General Cancer Center, Center for Cancer Research
Recent Article
Inactivating Mutation in the Histone Deacetylase SIRT6 Discovered to Be a Cause of Fetal Demise
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Whitfield B. Growdon, MD
Center for Gynecologic Oncology
Recent Article
Understanding the Molecular Underpinnings of Gynecologic Cancers
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology
Recent Article
Case Reports: Mapping of the Thalamocortical Tract in Asleep Craniotomies
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
