Specialty Oncology
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Featured
Biomarkers of T Cell Exhaustion in Checkpoint Inhibitor Therapy
Could altering the balance between two CD8+ T cell states enhance immunotherapies? Research from the Massachusetts General Hospital Cancer Center seeks to find the answer.
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Understanding the Molecular Underpinnings of Gynecologic Cancers
In this video, Whitfield Growdon, MD, of the Division of Gynecologic Oncology and the Mass General Cancer Center and a researcher in the Vincent Center for Reproductive Biology, discusses his research of the molecular underpinnings of cancer to someday create personalized medicine agendas for individuals.
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Screening for Pancreatic Cancer
Daniel Chung, MD, is the medical co-director of the Center for Cancer Risk Analysis in the Mass General Cancer Center. In this video, he discusses his work on pancreatic cancer screening and innovative ways to identify the people who are at the highest risk of this preventable disease.
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Review: Glioblastoma and Astrocytes Interactions, Mediated by Extracellular Vesicles, Affects Tumor Progression
A review by Xandra O. Breakefield, PhD and colleagues explains how extracellular vesicle–directed communication between glioblastoma cells and astrocytes changes astrocytes from protecting neurons to promoting tumor growth, migration and invasiveness.
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Using MicroRNA Profiling to Guide Osteosarcoma Treatment
Research at Massachusetts General Hospital is using microRNA technology to identify osteosarcoma patients who may need early surgery to prevent pathological fracture.
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Changes in DNA Structure with Aging Restrain Progression of Cancer
The DNA structure of normal cells breaks down as they age—but that can help prevent the development of cancer. Broadly speaking, the human genome is divided into an open, transcriptionally active inner layer of DNA (compartment A), where the genes most often used by cells are readily accessible, and a relatively...
Oncology contributors
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Andrew T. Chan, MD, MPH
Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
Physical Activity Reduces Chronic Liver Disease Mortality Risk -
David M. Langenau, PhD
Associate Professor of Pathology, Harvard Medical School, Associate Chair for Research, Department of Pathology, Massachusetts General Hospital
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J. Keith Joung, MD, PhD
Professor of Pathology, Harvard Medical School, Center for Cancer Research, Desmond and Ann Heathwood MGH Research Scholar
Recent Article
CRISPR Base Editors Can Induce Wide-Ranging Off-Target Edits in RNA -
Joseph H. Schwab, MD
Chief, Orthopaedic Spine Surgery, Director, Spine Oncology & Co-Director, Stephen L. Harris Chordoma Center, Associate Professor of Orthopedic Surgery, Harvard Medical School
Recent Article
Novel Technique Reconstructs Lumbar Spine After Spondylectomy of Malignant Tumor -
Keith T. Flaherty, MD
Director of Clinical Research, Mass General Cancer Center, Professor of Medicine, Harvard Medical School
Recent Article
Medical Grand Rounds: Advancing New Therapies for COVID-19: Antiviral, Immunomodulation and Beyond -
Marcela G. del Carmen, MD
Chief Medical Officer, Massachusetts General Physicians Organization, Gynecologic Oncologist, Center for Gynecologic Oncology
Recent Article
Changing Treatment Paradigms in Gynecologic Oncology -
Marcela V. Maus, MD, PhD
Director, Cellular Immunotherapy Program, Mass General Cancer Center, Assistant Professor of Medicine, Harvard Medical School
Recent Article
CAR T-cell Therapy Feasible for Active Secondary CNS Lymphoma -
Nir Hacohen, PhD
Director, MGH Center for Cancer Immunology
Center for Cancer Research , Professor of Medicine, Harvard Medical School, Senior Member, Broad InstituteRecent Article
MGH Research Scholars Respond to COVID-19 -
Raul Mostoslavsky, MD, PhD
Laurel Schwartz Professor of Medicine in the Field of Oncology, Mass General Cancer Center, Center for Cancer Research
Recent Article
Inactivating Mutation in the Histone Deacetylase SIRT6 Discovered to Be a Cause of Fetal Demise -
Whitfield B. Growdon, MD
Center for Gynecologic Oncology
Recent Article
Understanding the Molecular Underpinnings of Gynecologic Cancers -
William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology
Recent Article
Endonasal Surgery Using High-Speed Drill Puts Health Care Team at Risk of COVID-19