Nir Hacohen is an immunologist and geneticist focused on developing and applying unbiased methods to understand the mammalian immune response. His group is focused on several inter-related areas, including: (i) viral and bacterial sensing in dendritic cells, the sentinel cells of the immune system; (ii) detection of self vs. non-self by the innate immune system; (iii) genetic basis for the observed variation in immunity across the human population, with an emphasis on tumor immunity and autoimmunity; and (iv) novel and personalized immunotherapeutics. He is co-director of the Broad Cell Circuits Program, co-director of the Broad Center for Cell Circuits, and a founding PI of the Broad Genetic Perturbation Platform and Functional Genomics Consortium. Hacohen received an AB in physics from Harvard University and a PhD in biochemistry from Stanford University. After starting his own group as a Whitehead Institute Fellow, he moved to the Broad Institute and joined the faculties of Harvard Medical School and Massachusetts General Hospital.