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Featured
Preventing and Detecting Heart Injury in Cancer Patients
In this video, Tomas Neilan, MD, discusses the importance of detecting and preventing heart injury in cancer patients who receive chemotherapy.
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Featured
Flu Vaccination May Protect Against Myocarditis Related to Checkpoint Inhibitors
In a retrospective study, researchers at Massachusetts General Hospital have found evidence of a lower risk of myocarditis among cancer patients receiving immune checkpoint inhibitor therapy who have been vaccinated against influenza.
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Featured
Researchers Work to Reduce Heart Failure and Stroke After Radiation Therapy
The benefit of radiation and chemotherapy in treating cancer comes at the price of cardiovascular problems. Tomas G. Neilan, MD, and his team are identifying risk factors for heart problems and developing protocols to protect patients' hearts.
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Mosaic Chromosomal Alterations Increase the Risk of Diverse Infections
Pradeep Natarajan, MD, MMSc, of the Cardiovascular Research Center, and colleagues determined that mosaic chromosomal alterations (mCAs) are a risk factor for infectious disease, which is exacerbated in the setting of solid tumors. Furthermore, among COVID-19 patients, mCAs were linked to more severe disease.
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T1 Value on Cardiac MRI Diagnoses Myocarditis Associated with Checkpoint Inhibitors
Almost all patients with checkpoint inhibitor–associated myocarditis meet modified Lake Louise criteria for nonischemic myocardial injury on cardiac magnetic resonance. The T1 value also has a robust prognostic value.
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Immune Checkpoint Inhibitor Therapy Increases Risk of Atherosclerotic Cardiovascular Events
Massachusetts General Hospital researchers have found that patients treated with immune checkpoint inhibitors have higher rates of atherosclerotic cardiovascular events than other cancer patients, but the risk may be modifiable.
Mass General Cancer Center Contributors
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Jagmeet P. Singh, MD, PhD
Attending Physician, Telemachus & Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Massachusetts General Hospital, Professor of Medicine, Harvard Medical School
Recent Article
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Tomas G. Neilan, MD, MPH
Director, Cardio-Oncology Program, Massachusetts General Hospital, Co-Director, Cardiac MR PET CT Program
Recent Article
T1 Value on Cardiac MRI Diagnoses Myocarditis Associated with Checkpoint Inhibitors