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Featured
Brain Infusion of Genetically Modified Poliovirus Is Used to Treat Glioblastoma
A phase II trial kicked off at Massachusetts General Hospital involving multiple departments and research institutes are utilizing oncolytic viruses to treat glioblastomas.
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Featured
Combined Blockade of ATR and PARP Effective Against Glioblastoma in Mice
The combination of olaparib and an ATR inhibitor was effective against glioblastoma in mice, providing a much-needed therapeutic breakthrough for this deadly disease.
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Featured
Adding an NAMPT Inhibitor to Temozolomide Might Boost Its Effect in IDH-Mutant Glioma
IDH1/2-mutant glioma is often treated with temozolomide, but most of these cancers recur. Research at Massachusetts General Hospital suggests that combining the drug with an NAMPT inhibitor may improve its anticancer effect.
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The Future of Neurosurgery and Neuroscience at Mass General: Q&A With Bob S. Carter, MD, PhD
Bob S. Carter, MD, PhD, is the chief of the Department of Neurosurgery at Massachusetts General Hospital. In this Q&A, Dr. Carter elaborates on intraoperative molecular diagnostics. Dr. Carter is also a 2021 Congress of Neurological Surgeons (CNS) honored guest.
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Review: Novel Applications of Spinal Navigation in Deformity and Oncology Surgery
Elie Massaad, MD, and colleagues recently reviewed early work showing the promise of computer-assisted navigation—beyond screw placement—in surgeries to correct spinal deformities and resect spinal tumors.
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Review: Challenges in Discovering Extracellular Vesicle–based Cancer Biomarkers
Anudeep Yekula, MD, Leonora Balaj, PhD, and Bob S. Carter, MD, PhD, of the Department of Neurosurgery, highlight hurdles in the process of developing extracellular vesicle–based cancer biomarkers, from discovery to clinical application.
Mass General Cancer Center Contributors
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Bakhos A. Tannous, PhD
Associate Neuroscientist, Massachusetts General Hospital, Director, Vector Production and Development Core, Associate Professor, Harvard Medical School
Recent Article
Noninvasive Techniques in Brain Tumor Treatment -
Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
The Future of Neurosurgery and Neuroscience at Mass General: Q&A With Bob S. Carter, MD, PhD
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Daniel P. Cahill, MD, PhD
Neurosurgeon, Massachusetts General Hospital, Neurosurgical Oncologist, Mass General Cancer Center
Recent Article
Local NAMPT Inhibition Enhances Checkpoint Immunotherapy for Glioblastoma
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Shannon Stott, PhD
Assistant Professor of Medicine, Department of Medicine, Harvard Medical School, Assistant in Genetics, Massachusetts General Hospital
Recent Article
How Liquid Biopsies Can Improve Brain Tumor Diagnoses
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology
Recent Article
Review: Implications of IDH Mutations for Success of Glioma Immunotherapy
Stephen E. and Catherine Pappas Center for Neuro-Oncology at Mass General
The Stephen E. and Catherine Pappas Center for Neuro-Oncology offers the most advanced care for patients with brain tumors and nervous system tumors.
