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Featured
Brain Infusion of Genetically Modified Poliovirus Is Used to Treat Glioblastoma
A phase II trial kicked off at Massachusetts General Hospital involving multiple departments and research institutes are utilizing oncolytic viruses to treat glioblastomas.
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Featured
Combined Blockade of ATR and PARP Effective Against Glioblastoma in Mice
The combination of olaparib and an ATR inhibitor was effective against glioblastoma in mice, providing a much-needed therapeutic breakthrough for this deadly disease.
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Featured
Adding an NAMPT Inhibitor to Temozolomide Might Boost Its Effect in IDH-Mutant Glioma
IDH1/2-mutant glioma is often treated with temozolomide, but most of these cancers recur. Research at Massachusetts General Hospital suggests that combining the drug with an NAMPT inhibitor may improve its anticancer effect.
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Metastatic Spinal Tumor Frailty Index Does Not Perform Consistently
Surgeons at Massachusetts General Hospital found the Metastatic Spinal Tumor Frailty Index did not predict complications, in-patient mortality or length of stay following metastatic spinal tumor surgery when applied to data outside the development cohort.
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Genotyping Assay Accelerates Diagnosis of Primary CNS Lymphoma, Detects Other Hematologic Malignancies
Bob S. Carter, MD, PhD, and Ganesh M. Shankar, MD, PhD, of the Department of Neurosurgery, have developed a targeted genotyping assay that shortens the time to diagnosis of primary central nervous system lymphoma and may reduce the need for neurosurgical biopsy.
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Immunotherapies to Treat Glioblastoma
William T. Curry, MD, co-director of Mass General Neuroscience and director of Neurosurgical Oncology in the Department of Neurosurgery at Massachusetts General Hospital, discusses a four-center trial studying the use of poliovirus to treat malignant brain tumors.
Mass General Cancer Center
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Bakhos A. Tannous, PhD
Associate Neuroscientist, Massachusetts General Hospital, Director, Vector Production and Development Core, Associate Professor, Harvard Medical School
Recent Article
Noninvasive Techniques in Brain Tumor Treatment -
Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Genotyping Assay Accelerates Diagnosis of Primary CNS Lymphoma, Detects Other Hematologic Malignancies
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Daniel P. Cahill, MD, PhD
Neurosurgeon, Massachusetts General Hospital, Neurosurgical Oncologist, Mass General Cancer Center
Recent Article
Local NAMPT Inhibition Enhances Checkpoint Immunotherapy for Glioblastoma
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Shannon Stott, PhD
Assistant Professor of Medicine, Department of Medicine, Harvard Medical School, Assistant in Genetics, Massachusetts General Hospital
Recent Article
How Liquid Biopsies Can Improve Brain Tumor Diagnoses
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology
Recent Article
Immunotherapies to Treat Glioblastoma
Stephen E. and Catherine Pappas Center for Neuro-Oncology at Mass General
The Stephen E. and Catherine Pappas Center for Neuro-Oncology offers the most advanced care for patients with brain tumors and nervous system tumors.
