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Featured
Maximizing Clinical Utility of Pulmonary Optical Imaging
Massachusetts General Hospital researchers push the limits of pulmonary optical frequency domain imaging for in vivo diagnosis of lung cancer and assessment of asthmatic airways.
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Lymph Node Harvest, Upstaging After Lobectomy for NSCLC Linked to Hospital Volume
Henning A. Gaissert, MD, and colleagues reviewed a Society of Thoracic Surgeons database for 2012 to 2019 and report increased likelihood of nodal upstaging at hospitals that perform a low annual volume of lobectomies for non–small-cell lung cancer—but 25% of high-volume centers failed to harvest ≥10 nodes on average.
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Pulmonary Function at Time of Lung Cancer Diagnosis Has Prognostic Value
David C. Christiani, MD, MPH, and colleagues found in a large cohort of patients newly diagnosed with non–small-cell lung cancer that poorer spirometry results were linearly associated with worse survival, even after accounting for age, sex, smoking status, tumor histology, cancer stage, and types of treatment.
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Smoking History Predicts Efficacy of Immune Checkpoint Inhibitors in Metastatic Non–Small-Cell Lung Cancer
David C. Christiani, MD, MPH, and colleagues suggest smoking history as an independent surrogate for tumor mutation burden when deciding which patients with advanced non–small-cell lung cancer would benefit from immune checkpoint inhibitor therapy, as smoking pack-years complemented PD-L1 tumor proportion score.
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Paclitaxel-loaded Mesh Reduces Local Recurrence of Lung Cancer in Animal Model
Yolonda L. Colson, MD, PhD, and colleagues have developed a polymer mesh that can be loaded with a chemotherapeutic agent and implanted during resection to prevent local recurrence. Its use significantly improved survival in a mouse model of non–small-cell lung cancer.
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New AI Tool Predicts Six-Year Lung Cancer Risk From a Single CT Scan
Lecia V. Sequist, MD, MPH, Florian J. Fintelmann, MD, and colleagues have created and validated Sybil, a convolutional neural network that requires only one low-dose CT scan to predict future lung cancer, regardless of whether visible lung nodules are present and possibly independent of the patient's smoking history.
Lung Cancer Contributors
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Aaron Hata, MD, PhD
Assistant Physician, Hematology and Oncology, Massachusetts General Hospital, Assistant Professor of Medicine, Harvard Medical School
Recent Article
Study Provides Insight Into Overcoming Acquired Resistance to KRAS-G12C Inhibitors
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Aaron L. Baggish, MD
Director, Cardiovascular Performance Program, Director, Cardiovascular Performance Program Fellowship
Recent Article
How COVID-19 Affects the Heart, Especially in Athletes
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Gary X. Wang, MD, PhD
Diagnostic Radiologist, Department of Radiology, Massachusetts General Hospital
Recent Article
Some Physicians Knowingly Order Guideline-Discordant Lung Cancer Screening -
Melissa J. Suter, PhD
Associate Professor in Medicine, Harvard Medical School, Assistant in Biomedical Engineering, Massachusetts General Hospital
Recent Article
Maximizing Clinical Utility of Pulmonary Optical Imaging -
Michael T. Lu, MD, MPH
Director of Research, Cardiovascular Imaging Division, Co-Director, Cardiovascular Imaging Research Center, Massachusetts General Hospital, Assistant Professor of Radiology, Harvard Medical School
Recent Article
Q&A: AI Predicts 10-Year Risk of Heart Attack and Stroke from X-Ray Images -
Rebecca Suk Heist, MD, MPH
Associate Professor of Medicine at Harvard Medical School, Physician in the Division of Hematology/Oncology, Mass General Cancer Center
Recent Article
Study Provides Insight Into Overcoming Acquired Resistance to KRAS-G12C Inhibitors
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Udo Hoffmann, MD
Director, Cardiac MR PET CT Program, Mass General, Division Chief, Cardiovascular Imaging, Mass General, Professor of Radiology, HMS
Recent Article
Discordance Across High-Sensitivity Troponin Assays Can Affect Management of Suspected ACS
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
