Posts by Aaron Hata, MD, PhD
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Study Provides Insight Into Overcoming Acquired Resistance to KRAS-G12C Inhibitors
Researchers at the Massachusetts General Hospital Cancer Center and colleagues have identified mutations that make lung cancer resistant to adagrasib and other KRAS-G12C inhibitors. Their findings provide clues to designing next-generation inhibitors and combination regimens.
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MET Alterations Are a Recurring Resistance Mechanism in ALK-Positive Lung Cancer
Massachusetts General Hospital Cancer Center researchers find that ALK/MET combination therapy is a rational approach to treatment of ALK-positive non-small-cell lung cancer.
Biography
Assistant Physician, Hematology and Oncology, Massachusetts General Hospital