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Featured
New Strategies for Heart Failure Patients Improves Outcomes
One-third of heart failure patients do not respond to cardiac resynchronization therapy (CRT) | A coordinated care approach at Mass General for heart failure patients improves outcomes.
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Featured
The Promise of Ventricular-Assist Devices (VADs)
VAD technology is continually improving. Mass General data indicates new VADs improve 5-year survival rates. Trials for the latest generation are under way.
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Virtual Randomized Trial Feasible, Demonstrates Canagliflozin Relieves Symptom Burden in HF
James L. Januzzi, MD, and colleagues conducted a large randomized, placebo-controlled trial without any in-person visits, demonstrating canagliflozin was associated with a rapid and clinically meaningful improvement in the symptoms of heart failure regardless of ejection fraction and presence of diabetes.
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History of Infertility in Women Linked to Risk of Future Heart Failure
Emily S. Lau, MD, MPH, Jennifer E. Ho, MD, and colleagues found infertility in women is associated with a 16% greater risk of heart failure overall. This was driven by a 27% greater risk of heart failure with preserved ejection fraction, but not heart failure with reduced ejection fraction.
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Blood Pressure Assessment During Exercise Testing Aids Risk Stratification of Patients With Heart Failure
Mayooran Namasivayam, MBBS, PhD, Gregory D. Lewis, MD, and colleagues demonstrated that lower proportionate pulse pressure during exercise testing of patients who have heart failure with preserved ejection fraction is associated with a 47% reduced risk of adverse cardiovascular outcomes.
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Acetylcholine Derived From B Cells May Protect Against Cardiovascular Disease
B cells in the bone marrow are an important source of acetylcholine, Massachusetts General Hospital researchers have discovered. B cell–derived acetylcholine regulated normal hematopoiesis and limited emergency hematopoiesis in cardiovascular disease by modulating signals produced by the bone marrow stromal niche.
Heart Failure Contributors
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James Louis Januzzi, MD
Hutter Family Professor of Medicine, Director, Dennis and Marilyn Barry Fellowship in Cardiology Research
Recent Article
Virtual Randomized Trial Feasible, Demonstrates Canagliflozin Relieves Symptom Burden in HF
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Thoralf M. Sundt, MD
Chief, Division of Cardiac Surgery, Co-Director, Corrigan Minehan Heart Center, Director, Cardiac Surgery Clinical Service, Mass General Brigham
Recent Article
Treating Pericardial Disease
Cardiovascular Care at Mass General
At Mass General, our world-class physicians and nurses specialize in specific forms of both heart and vascular disease, and work closely together to offer leading treatments and preventive care for cardiovascular conditions.