Natalia S. Rost, MD, MPH, FAAN, is chief of Stroke Division at Massachusetts General Hospital Department of Neurology and professor of neurology at Harvard Medical School. A cum laude graduate of Boston University School of Medicine, she also holds a master's degree from Harvard School of Public Health. Rost trained in neurology and vascular neurology at Partners (Massachusetts General Hospital/Brigham and Women's Hospital) residency and fellowship programs.
Rost is a clinician-scientist and international expert on neuroimaging markers of cerebrovascular disease, stroke genetics, and big data science for outcome prediction in patients with acute stroke. Her line of research on the role of white matter disease burden and mechanisms of brain resilience in stroke has been continuously funded since 2007, and Rost is currently principal investigator of two NIH R01 awards and is the Samana Cay MGH Research Scholar. As of September 2019, Rost leads DISCOVERY (Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY), a new collaborative national network supported jointly by the National Institute of Neurological Disorders and Stroke/National Institute of Aging (U19NS115388), which consists of 4 cores and 30 premier academic clinical sites with access to acute stroke populations and the expertise and capacity for systematic assessment of post-stroke cognitive impairment and dementia. DISCOVERY will become a landmark study to unravel the mechanisms of post-stroke cognitive disability, early stroke recovery, and potential targets for personalized stroke prevention, intervention, and rehabilitation.
Rost is an author of numerous peer-reviewed publications, book chapters, a co-author of the MGH Handbook of Neurology, and medical editor of the Harvard Medical School Special Health Report on stroke. She is an accomplished mentor, clinical educator, and recipient of the 2017 MGH Neurology Department’s Ray Adams Clinical Mentor Award and of the 2012 Michael S. Pessin Stroke Leadership Award from the American Academy of Neurology. She serves as Assistant Editor of the journal Stroke and Chair of the Science Committee of the American Academy of Neurology.