Posts by Lorenzo Berra, MD
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Inhaled Nitric Oxide Improves Oxygenation in Pregnant Patients With COVID-19 Pneumonia
A team of researchers led by Massachusetts General Hospital found that high dose inhaled nitric oxide gas safely improved oxygenation and reduced hospital lengths of stay for pregnant patients hospitalized with severe COVID-19 pneumonia.
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High-dose Inhaled Nitric Oxide Safe, Effective for Non-Intubated COVID-19 Patients
Lorenzo Berra, MD, and Bijan Safaee Fakhr, MD, of the Department of Anesthesia, Critical Care and Pain Medicine, and colleagues found that high-dose inhaled nitric oxide produced a beneficial effect on the respiratory system of non-intubated hospitalized COVID-19 patients without adverse events.
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COVID-19 ARDS Has Distinct Phenotypes Different from Those in "Classic" ARDS
Massachusetts General Hospital physicians have identified two phenotypes of acute respiratory distress syndrome (ARDS) associated with COVID-19 that are distinct in biochemical profiles and short-term mortality despite minimal differences in respiratory dynamics.
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Case Series: Inhaled Nitric Oxide as Rescue Therapy for Nonintubated Patients with Severe COVID-19
Lorenzo Berra, MD, and Bijan Safaee Fakhr, MD, of the Department of Anesthesia, Critical Care and Pain Medicine, report that administering high-dose nitric oxide to non-intubated critically ill patients with COVID-19 was feasible and well tolerated.
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Case Series: Inhaled Nitric Oxide for Pregnant Patients with Severe or Critical COVID-19
High-dose nitric oxide gas rapidly improved shortness of breath in six pregnant patients who had severe or critical COVID-19, and in five cases viral infection resolved within 28 days.
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Review: How to Make ICUs More Geriatrics-friendly
Treatment decisions in the ICU should account for life expectancy but also be tailored to the needs and wishes of patients and next-of-kin.
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Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients
In this Q&A, Lorenzo Berra, MD, and Charles Hardin, MD, PhD, of Massachusetts General Hospital explain the link between acute respiratory distress syndrome (ARDS) and share insight into upcoming research on antiviral treatment approaches.
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Individually Titrated Mechanical Ventilation Improves Survival of Severely Obese ARDS Patients
Massachusetts General Hospital researchers have pioneered an individualized approach to the care of patients with acute respiratory distress syndrome and class III obesity who are receiving mechanical ventilation.
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Inhaled Nitric Oxide Could Reduce Kidney Problems After Heart Surgery
A study led by Mass General’s Lorenzo Berra, MD, found that administering nitric oxide to patients during or after heart surgery may be protective against future kidney disorders.
Biography
After his medical school at the University of Milan, Dr. Berra spent three years under the mentorship of Dr. Theodor Kolobow in a research laboratory at the National Institutes of Health (Bethesda, MD). From 2006-2011 he completed his residency in Anesthesia and fellowship in Critical Care both at the Department of Anesthesia, Critical Care and Pain Medicine at Mass General. Since 2011 he is a staff anesthesiologist and intensivist and a member of Dr. Warren Zapol's MGH Anesthesia Center for Critical Care Research. His current patient care activities are focused on caring for critically ill patients and their families. His primary research and academic interests involve translational research to improve diagnosis, treatment and care of critically ill patients with cardio-pulmonary failure or severe infections