Posts by Meredith Gregory-Ksander, PhD
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Turning Back the Clock on Aged Eye Cells
A team of researchers at Mass Eye and Ear and Harvard Medical School have successfully restored vision in elderly mice by turning back the clock on their aged nerve cells in the retina to recapture their youthful function.
Biography
Dr. Gregory-Ksander has a longstanding interest in how age-related changes in immune privilege and subsequent inflammation contributes to the development of ocular disease. The current research in Dr. Gregory-Ksander’s lab at Schepens Eye Research Institute at Mass Eye and Ear is specifically focused on how age-related changes in immune privilege and subsequent inflammation contributes to the development of glaucoma and age-related macular degeneration (AMD). Using animal models of glaucoma and AMD, Dr. Gregory-Ksander has identified Fas ligand (FasL) and the NLRP3 inflammasoma as two critical mediators of ocular inflammation and current studies focus on how age-related changes in FasL and the NLRP3 inflammasome contribute to the development of inflammation associated with glaucoma and AMD.
Mass Eye and Ear/Mass General Ophthalmology
An international center for ophthalmology treatment and research, Mass Eye and Ear/Massachusetts General Hospital is the primary teaching hospital of Harvard Medical School’s Department of Ophthalmology, and is consistently recognized as one of the nation’s top hospitals for eye care. Led by Chief and Chair Joan W. Miller, MD, the department provides seamless access to the most innovative care available anywhere in the world.
