Posts by Todd M. Herrington, MD, PhD
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Co-transplantation of Regulatory T Cells Improves Cell Replacement Therapy for Parkinson's Disease
Research at Massachusetts General Hospital suggests a novel strategy for enhancing the efficacy and safety of cell replacement therapy in the nervous system: co-transplantation of dopamine progenitor cells with regulatory T cells to modulate the host immune response triggered by needle trauma.
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Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
Massachusetts General Hospital and McClean Hospital researchers take significant steps towards proving the safety and efficacy of dopaminergic neuron implantation to treat Parkinson's disease.
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Collaboration in Developing New Cell Therapy
In this video, Bob S. Carter, MD, PhD, Kwang-Soo Kim, PhD, Todd M. Herrington, MD, PhD, and Jeffrey S. Schweitzer, MD, PhD, discuss their cross-disciplinary and multi-institutional collaboration to develop this new therapy.
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First-In-Human Therapy with Stem Cell–derived Dopaminergic Progenitor Cells for Parkinson's Disease
Mass General researchers report substantial clinical improvement in a patient with Parkinson's disease after they implanted midbrain dopaminergic progenitor cells that they differentiated in vitro from autologous induced pluripotent stem cells.
Biography
Todd Herrington is a neurologist at Massachusetts General Hospital and assistant professor of Neurology at Harvard Medical School. Dr. Herrington completed his BS at Stanford University, followed by MD and PhD at Harvard Medical School, residency in Neurology at the joint Partners Neurology Residency Program at Massachusetts General Hospital and Brigham and Women's Hospital, and a Fellowship in Movement Disorders at Mass General.
In the Division of Movement Disorders, Dr. Herrington treats patients with Parkinson's disease, tremor, dystonia and other movement disorders, with an additional specialization in patients who are undergoing treatment with deep brain stimulation.
Dr. Herrington's research focuses on the impact of deep brain stimulation on the motor, cognitive and psychiatric manifestations of movement disorders. Using a combination of intraoperative neurophysiology, noninvasive neurophysiology and neuroimaging, Dr. Herrington aims to further our understanding of the role of the human basal ganglia in health and disease and to develop novel approaches to neuromodulation to treat motor and nonmotor symptoms.
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