Specialty Oncology
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Featured
Mass General Offers Novel, Kidney-saving Urothelial Cancer Treatment
Mitomycin chemoablation with a mitomycin gel, a novel treatment offered in the Department of Urology at Massachusetts General Hospital, can avoid the need for surgical removal of the kidney and ureter in patients with upper tract urothelial cancer.
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Featured
Using Machine Learning to Predict Prostate Cancer Progression During Active Surveillance
Madhur Nayan, MDCM, PhD, and Adam S. Feldman, MD, MPH, and colleagues created the first machine learning models for predicting prostate cancer progression during active surveillance and found they outperformed traditional logistic regression.
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Primary Prostate Cancer Establishes a Suppressive Immune Microenvironment
Through careful unraveling of the cellular and molecular landscape of prostate cancer, Massachusetts General Hospital researchers observed a highly immune-suppressive tumor microenvironment with a pattern of angiogenic gene expression, findings that will help identify targets amenable to therapeutic interventions.
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Lymph Node Evaluation Underutilized for Early-stage Vulvar Cancer
Massachusetts General Hospital researchers found in a nationwide study that contrary to guidelines, 34% of eligible patients with early-stage vulvar cancer did not undergo lymph node evaluation. Among patients 80 and older, the figure was 49%, even though withholding lymph node assessment did not improve survival.
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Targeting Lipid Synthesis Efficacious in Glioblastoma Mouse Models
Katharina M. Eyme, Alessandro Sammarco, PhD, Christian E. Badr, PhD, and colleagues found YTX-7739, an orally available stearoyl coenzyme A desaturase 1 inhibitor, triggered lipotoxicity in glioblastoma stem-like cells, and with or without temozolomide, it was efficacious in mouse models of glioblastoma.
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Cancer Equity Colloquium: Q&A With Colin Weekes, MD, PhD
Colin Weekes, MD, PhD, director of Medical Oncology Research for Pancreatic Cancer and director of the Cancer Center Grand Rounds Program, shares more about the origins of the Cancer Equity Colloquium and what attendees can expect from this year's two-day, hybrid event in Boston.
Mass General Cancer Center Contributors
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Andrew T. Chan, MD, MPH
Daniel K. Podolsky Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
Maternal Consumption of Ultra-processed Foods Linked to Weight Gain in Offspring
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Areej R. El-Jawahri, MD
Hematologist, Mass General Cancer Center, Assistant in Medicine, Massachusetts General Hospital, Instructor in Medicine, Harvard Medical School
Recent Article
Improved Coping Explains Benefits of Integrated Palliative Care for Patients With Acute Myeloid Leukemia
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Chin-Lee Wu, MD, PhD
Director, Genitourinary Pathology Service, Massachusetts General Hospital and Mass General Cancer Center, Professor of Pathology, Harvard Medical School
Recent Article
Case Series: Mucinous Adenocarcinoma of the Prostatic Urethra After Brachytherapy for Prostatic Adenocarcinoma
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Joseph H. Schwab, MD, MS
Chief, Orthopaedic Spine Surgery, Director, Spine Oncology & Co-Director, Stephen L. Harris Chordoma Center, Associate Professor of Orthopaedic Surgery, Harvard Medical School
Recent Article
Neighborhood Vulnerability Index Identifies Spine Clinic Patients With Limited Health Literacy
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Keith T. Flaherty, MD
Director of Clinical Research, Mass General Cancer Center, Professor of Medicine, Harvard Medical School
Recent Article
37 Biopsies, Nine Years: Mapping Evolution of Resistance to Melanoma Immunotherapy in a Former Complete Responder
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Keyan Salari, MD, PhD
Urologic Surgeon, Department of Urology, Massachusetts General Hospital, Urologic Oncologist, Mass General Cancer Center, Director, Prostate Cancer Genetics Program
Recent Article
Review: Biomarkers in Testicular Cancer
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Marcela G. del Carmen, MD
Chief Medical Officer, Massachusetts General Physicians Organization and Massachusetts General Hospital, Gynecologic Oncologist, Department of Obstetrics and Gynecology, Clinician, Center for Gynecologic Oncology, Mass General Cancer Center
Recent Article
Lymph Node Evaluation Underutilized for Early-stage Vulvar Cancer
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Marcela V. Maus, MD, PhD
Director, Cellular Immunotherapy Program, Mass General Cancer Center, Associate Professor of Medicine, Harvard Medical School
Recent Article
Distinct Cellular Dynamics Are Associated With Response to CAR-T Therapy for B-Cell Lymphoma
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Nir Hacohen, PhD
Director, MGH Center for Cancer Immunology
Center for Cancer Research , Professor of Medicine, Harvard Medical School, Senior Member, Broad InstituteRecent Article
Considering Both Tumor and Immune Features May Improve Prediction of Melanoma Outcomes After Checkpoint Inhibition
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology, Massachusetts General Hospital, Adeline Rose Wydotis Professor of Neurosurgery, Harvard Medical School
Recent Article
Designing Leading-Edge Immunotherapy for Brain Cancer
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
