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Featured
YAP1 Oncogene Synergizes with HPV to Promote Cervical Cancer
Researchers have provided in vitro and in vivo evidence that the YAP1 oncogene can induce cervical cancer regardless of HPV infection. Further, the synergism between HPV and YAP1 significantly accelerates the development of cervical cancer and HPV vaccination remains vitally important.
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Featured
Minimally Invasive Surgery Linked to Shorter Survival in Early-Stage Cervical Cancer
Among women with early-stage cervical cancer who undergo radical hysterectomy, survival after minimally invasive surgery is significantly shorter than after open surgery, according to the largest-ever investigation of this question.
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Featured
Combination Immunotherapy May Be the Best Treatment for Certain Uterine Cancers
Mass General researchers evaluated patients with six uterine cancer subtypes to identify those with the most potential for immunotherapy treatment.
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Early Detection of Ovarian Cancer via Biomarker Discovery in Uterine Lavage
Massachusetts General Hospital researchers recently received an award from The Prevent Cancer Foundation to fund their research in ovarian cancer early detection.
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Comprehensive Lymphadenectomy Often Not Necessary in Surgical Management of Primary Endometrioid Ovarian Carcinoma
Varvara Mazina, MD, Marcela G. del Carmen, MD, MPH, and colleagues showed in a retrospective cohort of 63 women with primary endometrioid ovarian cancer that all pelvic and para-aortic lymph nodes removed were negative for carcinoma and comprehensive cancer staging had no effect on progression-free or overall survival.
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Review: Barriers to Cervical Cancer Prevention in Ukraine
Annekathryn Goodman, MD, gynecologic oncologist and co-director of Women's Global Health at Massachusetts General Hospital, and colleagues have documented a need for Ukraine to expand awareness of and access to cervical cancer screening and human papillomavirus vaccination programs.
Mass General Cancer Center Contributors
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Cheng Wang, PhD
Associate Investigator, Vincent Center for Reproductive Biology, Associate Professor of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School
Recent Article
Cervical Cancer: Oncogene YAP1 Plays Central Role in Unconventional Carcinogenesis Mechanism -
Eric L. Eisenhauer, MD
Chief, Division of Gynecologic Oncology, Massachusetts General Hospital
Recent Article
Lymph Node Evaluation Underutilized for Early-stage Vulvar Cancer -
Marcela G. del Carmen, MD, MPH
President, Massachusetts General Physicians Organization, Gynecologic Oncologist, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Executive Vice President, Mass General Brigham
Recent Article
Comprehensive Lymphadenectomy Often Not Necessary in Surgical Management of Primary Endometrioid Ovarian Carcinoma -
Mary E. Sabatini, MD, PhD
Medical Director, Clinic for Reproductive Health and Cancer, Medical Director, Third Party Reproduction
Recent Article
The Müllerian Inhibiting Substance: Changing the Fertility Landscape for Young Women with Cancer