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Featured
YAP1 Oncogene Synergizes with HPV to Promote Cervical Cancer
Researchers have provided in vitro and in vivo evidence that the YAP1 oncogene can induce cervical cancer regardless of HPV infection. Further, the synergism between HPV and YAP1 significantly accelerates the development of cervical cancer and HPV vaccination remains vitally important.
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Featured
Minimally Invasive Surgery Linked to Shorter Survival in Early-Stage Cervical Cancer
Among women with early-stage cervical cancer who undergo radical hysterectomy, survival after minimally invasive surgery is significantly shorter than after open surgery, according to the largest-ever investigation of this question.
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Featured
Combination Immunotherapy May Be the Best Treatment for Certain Uterine Cancers
Mass General researchers evaluated patients with six uterine cancer subtypes to identify those with the most potential for immunotherapy treatment.
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Cervical Cancer: Oncogene YAP1 Plays Central Role in Unconventional Carcinogenesis Mechanism
The etiology of cervical cancer is not well understood, but new data suggest human papillomavirus infection is not necessary and hyperactivation of the oncogene YAP1 alone can drive cervical carcinogenesis.
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Quality of Life Needs Attention in Ovarian Cancer Patients Receiving Chemotherapy in Low-Income Countries
Annekathryn Goodman, MD, MPH, gynecologic oncologist and co-director of Women's Global Health, and colleagues documented that distressing physical and psychological symptoms, deteriorating emotional function and financial difficulties negatively affected quality of life among women with ovarian cancer in Bangladesh.
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How Research Has Impacted Care for Cervical Cancer video
In this video, Marcela del Carmen, MD, a gynecologic oncologist in the Department of Obstetrics and Gynecology at Massachusetts General Hospital, discusses how clinical care led to research and ultimately informed surgical approaches to cervical cancer.
Mass General Cancer Center Contributors
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Cheng Wang, PhD
Associate Investigator, Vincent Center for Reproductive Biology, Associate Professor of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School
Recent Article
Cervical Cancer: Oncogene YAP1 Plays Central Role in Unconventional Carcinogenesis Mechanism
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Eric L. Eisenhauer, MD
Chief, Division of Gynecologic Oncology, Massachusetts General Hospital
Recent Article
Review: Prophylactic Surgery for Women at Risk of Hereditary Ovarian or Endometrial Cancer -
Marcela G. del Carmen, MD
Chief Medical Officer, Massachusetts General Physicians Organization and Massachusetts General Hospital, Gynecologic Oncologist, Department of Obstetrics and Gynecology, Clinician, Center for Gynecologic Oncology, Mass General Cancer Center
Recent Article
U.S. COVID-19 Test Results Strongly Correlate with Race/Ethnicity, Income
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Mary E. Sabatini, MD, PhD
Medical Director, Clinic for Reproductive Health and Cancer, Medical Director, Third Party Reproduction
Recent Article
The Müllerian Inhibiting Substance: Changing the Fertility Landscape for Young Women with Cancer
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
