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Featured
YAP1 Oncogene Synergizes with HPV to Promote Cervical Cancer
Researchers have provided in vitro and in vivo evidence that the YAP1 oncogene can induce cervical cancer regardless of HPV infection. Further, the synergism between HPV and YAP1 significantly accelerates the development of cervical cancer and HPV vaccination remains vitally important.
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Featured
Minimally Invasive Surgery Linked to Shorter Survival in Early-Stage Cervical Cancer
Among women with early-stage cervical cancer who undergo radical hysterectomy, survival after minimally invasive surgery is significantly shorter than after open surgery, according to the largest-ever investigation of this question.
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Featured
Combination Immunotherapy May Be the Best Treatment for Certain Uterine Cancers
Mass General researchers evaluated patients with six uterine cancer subtypes to identify those with the most potential for immunotherapy treatment.
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Lymph Node Evaluation Underutilized for Early-stage Vulvar Cancer
Massachusetts General Hospital researchers found in a nationwide study that contrary to guidelines, 34% of eligible patients with early-stage vulvar cancer did not undergo lymph node evaluation. Among patients 80 and older, the figure was 49%, even though withholding lymph node assessment did not improve survival.
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Review: Lesions of the Ovary and Fallopian Tube
Rachel C. Sisodia, MD, and Marcela G. del Carmen, MD, MPH, emphasize that all patients with a high-risk lesion of the ovary or fallopian tube should be referred to a gynecologic oncologist, as multiple studies have shown comprehensive surgical staging and tumor debulking is associated with improved overall survival.
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Prophylactic Surgery for Patients at High Risk of Ovarian Cancer Decreases Sexual Function, Quality of Life
Researchers in the Center for Gynecologic Oncology found that among patients at high genetic risk of ovarian cancer who undergo prophylactic surgery, health-related worry and tension decline post-operatively, but sexual dysfunction and short-term quality of life are poorer.
Mass General Cancer Center Contributors
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Cheng Wang, PhD
Associate Investigator, Vincent Center for Reproductive Biology, Associate Professor of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School
Recent Article
Cervical Cancer: Oncogene YAP1 Plays Central Role in Unconventional Carcinogenesis Mechanism
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Eric L. Eisenhauer, MD
Chief, Division of Gynecologic Oncology, Massachusetts General Hospital
Recent Article
Lymph Node Evaluation Underutilized for Early-stage Vulvar Cancer -
Marcela G. del Carmen, MD
Chief Medical Officer, Massachusetts General Physicians Organization and Massachusetts General Hospital, Gynecologic Oncologist, Department of Obstetrics and Gynecology, Clinician, Center for Gynecologic Oncology, Mass General Cancer Center
Recent Article
Lymph Node Evaluation Underutilized for Early-stage Vulvar Cancer
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Mary E. Sabatini, MD, PhD
Medical Director, Clinic for Reproductive Health and Cancer, Medical Director, Third Party Reproduction
Recent Article
The Müllerian Inhibiting Substance: Changing the Fertility Landscape for Young Women with Cancer
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
