Posts by Cheng Wang, PhD
-
Cervical Cancer: Oncogene YAP1 Plays Central Role in Unconventional Carcinogenesis Mechanism
The etiology of cervical cancer is not well understood, but new data suggest human papillomavirus infection is not necessary and hyperactivation of the oncogene YAP1 alone can drive cervical carcinogenesis.
-
YAP1 May Be a Treatment Target for Certain Types of Female Subfertility
In vitro and in vivo results indicate that timely expression and activation of YAP1 is essential for ovarian follicle development and successful reproduction.
-
YAP1 Oncogene Synergizes with HPV to Promote Cervical Cancer
Researchers have provided in vitro and in vivo evidence that the YAP1 oncogene can induce cervical cancer regardless of HPV infection. Further, the synergism between HPV and YAP1 significantly accelerates the development of cervical cancer and HPV vaccination remains vitally important.
Biography
Cheng Wang, PhD, is a researcher at the Vincent Center for Reproductive Biology at Massachusetts General Hospital investigating the role of the Hippo/YAP signaling pathway in ovarian cancer.
Obstetrics & Gynecology Care at Mass General
The Mass General Department of Obstetrics & Gynecology offers the highest level of care to women. Our clinical and research team is a leader in advancing treatments for gynecologic cancers, menopause, high-risk obstetrics, infertility and urogynecology.