Specialty Neuroscience
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Featured
Closing the Health Equity Gap in Neurosurgical Care
Neurosurgeon Theresa Williamson, MD, a Massachusetts General Hospital physician-scientist and medical ethicist, studies decision-making and health care disparities in neurosurgery.
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Featured
Mass General Renews Focus on Pediatric Epilepsy
A new team approach at Mass General is applying advances in adult epileptics, such as epilepsy surgery and responsive neurostimulation, to children.
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Antisense Drugs Mimic TDP-43 Function, Might Treat ALS and Some Dementias
Clotilde Lagier-Tourenne, MD, PhD, and colleagues have demonstrated in vitro and in vivo efficacy of antisense oligonucleotides in preventing missplicing of stathmin-2 in a mouse model of amyotrophic lateral sclerosis attributable to deficiency of the protein TDP-43.
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Design and Statistical Innovations in the Healey ALS Platform Trial
Sabrina Paganoni, MD, PhD, Eric A. Macklin, PhD, and colleagues explain the statistical approaches used in the Healey ALS Platform Trial to integrate functional and survival outcomes and account for potential differences in the outcomes of participants within the shared control group.
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Genomic Therapeutics in Action: Antisense Oligonucleotides Interventions Reverses Neurodegeneration
Physician-investigators at Massachusetts General Hospital recently published findings that provide a critical step forward in understanding the mechanisms underlying a host of neurodegenerative diseases.
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Co-Occurring Cardiovascular/Metabolic Abnormalities Linked to Widespread Alterations In Brain Connectivity
Barnaly Rashid, PhD, Steven E. Arnold, MD, and colleagues report that, across the adult lifespan, worse cardiometabolic health associates with dysregulated functional connectivity throughout the brain, including in higher-order brain networks vital to cognitive function. The effect was strongest in adults under age 65.
Neuroscience Contributors
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Aman B. Patel, MD
Director of Cerebrovascular and Endovascular Neurosurgery, Co-Director of the Neuroendovascular Program
Recent Article
Case Report: Direct Burr Hole Access for Embolization of Dural Arteriovenous Fistula
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Co-transplantation of Regulatory T Cells Improves Cell Replacement Therapy for Parkinson's Disease
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Novel Target Identified for Treatment of ALS
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Jill M. Goldstein, PhD
Founder & Executive Director, Innovation Center on Sex Differences in Medicine, Massachusetts General Hospital, Helen T. Moerschner Endowed MGH Research Institute Chair in Women’s Health, Professor of Psychiatry & Medicine, Harvard Medical School
Recent Article
Effect of Hypertension on Midlife Cognition May Be Detrimental in Women
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Jordan W. Smoller, MD, ScD
Associate Chief for Research, Department of Psychiatry, Massachusetts General Hospital, Director, Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health
Recent Article
Psychiatric Disorders Not Associated With Incidental Findings in Medically Actionable Genes
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Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
AI Approach Can Predict Placebo Responders in Clinical Trials in Major Depressive Disorder
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Merit Ester Cudkowicz, MD, MSc
Chief, Neurology Service, Director of the Sean M. Healey & AMG Center for ALS at Mass General, Director of Neurological Clinical Research Institute and the Jilieane Dorn Professor of Neurology, Harvard Medical School
Recent Article
ALS Therapy Research and Development: Insights from Merit Cudkowicz, MD, MSc
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Natalia S. Rost, MD, MPH, FAAN
Chief of Stroke Division, Department of Neurology, Massachusetts General Hospital, Professor of Neurology, Harvard Medical School
Recent Article
Multiple Lesions Are More Frequent Than Previously Thought in Acute Ischemic Stroke
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Rudolph E. Tanzi, PhD
Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School, Vice-Chair, Massachusetts General Hospital Neurology Department, Co-Director of the McCance Center for Brain Health, Massachusetts General Hospital
Recent Article
How Amyloid-beta Forms Suggests New Strategies for Preventing, Treating Alzheimer's Disease
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Timothy Wilens, MD
Chief, Division of Child and Adolescent Psychiatry, Massachusetts General Hospital, Co-director, Center for Addiction Medicine, Director, Substance Abuse Services in Pediatric Psychopharmacology
Recent Article
Treatment for Substance Use Disorder Reduces Risk of Overdose in Young Adults
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology, Massachusetts General Hospital, Adeline Rose Wydotis Professor of Neurosurgery, Harvard Medical School
Recent Article
Novel Tandem CAR T-Cell Effective Against Heterogeneous Glioblastoma
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Ziv Williams, MD
Neurosurgeon, Department of Neurosurgery, Massachusetts General Hospital, Associate Professor in Neurosurgery, Harvard Medical School
Recent Article
Interim Safety Profile From the Feasibility Study of the BrainGate Neural Interface System
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.