Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Digestive Health
AGA Guideline Makes the Case for Biomarkers in Managing Crohn's Disease
Ashwin Ananthakrishnan, MD, discusses the AGA guideline's key recommendations for managing Crohn's disease and the evolving role of biomarkers in these treatments.
Featured In Oncology
Revolutionizing Cancer Immunotherapy for Melanoma and Beyond
Researchers at Massachusetts General Hospital won a Breakthrough Award to enhance personalized approaches to immunotherapy for metastatic melanoma.
Featured In Otolaryngology
CRISPR-Cas9 Genome Editing Treats Genetic Hearing Loss by Promoting Outer Hair Cell Survival
Yong Tao, PhD, Veronica Lamas, PhD, and Zheng-Yi Chen, DPhil, have extended their previous murine research to show CRISPR-associated protein 9 (Cas9)-based genome editing can treat hearing loss associated with monogenic mutations in outer hair cell genes and digenic mutations affecting both inner and outer hair cells.
Featured In Cardiovascular
New Program Helps High School Students Explore Careers in Cardiology
A Massachusetts General Hospital cardiology fellow launched You Belong in Cardiology to build a pipeline for women and underrepresented minorities in cardiology.
Featured In Neuroscience
New Website Allows Provider Consultations for Patients With Restless Leg Syndrome
A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives.
The Latest Ophthalmology Advances
Compassionomics: The Science and Practice of Caring
Inês Laíns, MD, PhD, and colleagues summarize the robust scientific evidence that compassion can measurably improve patient outcomes and the well-being of healthcare providers. They outline strategies for measuring compassion, and to train and cultivate compassionate care.
The Neuropeptide Alpha-Melanocyte–stimulating Hormone Prevents Persistent Corneal Edema After Injury
Reza Dana, MD, MSc, MPH; Jia Yin, MD, PhD, MPH; Ula V. Jurkunas, MD; and colleagues have discovered a critical role for neuropeptides in maintenance of corneal endothelial cells and potential therapeutic applications for α-melanocyte–stimulating hormone after corneal injury or intraocular surgery.
Contributing Physicians
Anna M. Stagner, MD
Frederick A. Jakobiec Director of the David Glendenning Cogan Laboratory of Ophthalmic Pathology, Fellowship Director, Ophthalmic Pathology, Mass Eye and Ear, Assistant Professor of Ophthalmology, Harvard Medical School
Reza Dana, MD, MSc, MPH
Director, Cornea Service, Associate Chief for Academic Programs, Mass Eye and Ear, Claes H. Dohlman Professor of Ophthalmology, Harvard Medical School
Advances Specialties
Endocrinology
In Utero Exposure to SARS-CoV-2 May Increase the Risk of Cardiometabolic Disease
Massachusetts General Hospital researchers found that infants who have in utero exposure to maternal SARS-CoV-2 exhibit lower birth weight followed by accelerated weight gain in the first year of life, a pattern thought to increase the risk of obesity and cardiometabolic disease in childhood and adulthood.
Orthopaedics
Chondrolabral Junction Breakdown Predicts Progression to THA After Hip Arthroscopy for Labral Tears
Michael C. Dean, BA, Scott D. Martin, MD, and colleagues are the first to identify chondrolabral junction breakdown, observed intraoperatively, as a risk factor for eventual conversion to total hip arthroplasty after hip arthroscopy for symptomatic labral tears secondary to femoroacetabular impingement.
Rheumatology, Allergy and Immunology
Pathways Case Record: An Immunocompetent Patient With Disseminated CMV
A 49-year-old male presented to Massachusetts General Hospital, found to have new heart failure with a reduced ejection fraction and pericardial effusion. Testing revealed elevated cytomegalovirus (CMV) viral load, so the Pathways Service investigated how a previously immunocompetent patient developed CMV reactivation.
May 10, 2024
Conference: Midlife Women's Health 2024: A Multidisciplinary Approach to Care
The Midlife Women's Health 2024 course is led by a multidisciplinary group of experts from Massachusetts General Hospital who will present on the evaluation and management of gynecologic cancers, cardiovascular health, menopausal hormone therapy, ADHD, sexuality after cancer, and more to assist clinicians in caring for their midlife patients. The entire program will be available to registrants for 30 days after the event, with CME credit provided only to those who log in on the day of the conference.
May 4-8, 2024
Conference: American Psychiatric Association 2024 Annual Meeting
Considered the premier psychiatry event of the year, the American Psychiatric Association's 2024 Annual Meeting takes place May 4–8 in New York City. The Department of Psychiatry at Massachusetts General Hospital will present their latest research at this year's event.
