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Featured
An Estimate for Hidden Hearing Loss
In one of the largest retrospective studies of its kind, a group of Mass Eye and Ear researchers examined data from nearly 96,000 ears to develop a word-score model that can help estimate the amount of hidden hearing loss in humans.
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Innovations in Hearing and Vision Restoration Through Gene Therapy
Artur A. Indzhykulian, MD, PhD, is advancing gene therapies for sensory disorders like Usher syndrome, exploring innovative approaches to restore hearing, balance, and vision through cutting-edge research and cross-disciplinary collaboration.
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Establishing a Nonsyndromic Hearing Loss Gene
A robust collaboration between Mass Eye and Ear and Boston Children's Hospital resulted in discovering a novel gene for nonsyndromic hearing loss called PKHD1L1.
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Cochlear Organoids Shed Light on Hair Cell Regeneration for Hearing Loss Treatment
Albert Edge, PhD, and colleagues have developed murine cochlear organoids that show how sensory epithelial progenitor cells differentiate into hair cells, a potential step toward developing regenerative therapies for human hearing loss.
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Virally Mediated Gene Therapy Treats Genetic Hearing Loss in Aged Mouse Model
Zheng-Yi Chen, DPhil, and colleagues are the first to demonstrate rescue of genetic hearing loss with a gene therapy delivered by adeno-associated virus in an aged animal model. The study also serves as proof-of-principle that other gene therapies be developed for older adults.
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Prior Surgery No Barrier to Cochlear Implantation for Ménière's Disease
Steven D. Rauch, MD, and colleagues at Mass Eye and Ear found word recognition scores improve after cochlear implantation for deafness caused by Ménière's disease regardless of age at implantation and whether patients received previous medical or surgical Ménière's treatment.
Hearing Loss Contributors
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Albert Edge, PhD
Director, Tillotson Cell Biology Unit, Principal Investigator, Eaton-Peabody Laboratories, Mass Eye and Ear, Professor of Otolaryngology–Head and Neck Surgery, Harvard Medical School
Recent Article
Cochlear Organoids Shed Light on Hair Cell Regeneration for Hearing Loss Treatment
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David Y. Chung, MD, PhD
Attending Physician, Division of Neurocritical Units, Department of Neurology, Massachusetts General Hospital
Recent Article
Minimally Invasive Electrocorticography, Continuous EEG Do Not Reliably Detect Spreading Depolarizations -
Dunia Abdul-Aziz, MD
Physician-Surgeon, Mass Eye and Ear, Instructor in Otolaryngology–Head and Neck Surgery, Harvard Medical School
Recent Article
Discovery of New Molecular Player May Lead to Pathway for Hearing Loss Reversal
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Stéphane F. Maison, PhD, CCC-A
Principal Investigator, Eaton-Peabody Laboratories, Mass Eye and Ear, Associate Professor of Otolaryngology–Head and Neck Surgery, Harvard Medical School
Recent Article
New Biomarker for Cochlear Nerve Degeneration Proposed -
Steven D. Rauch, MD
Director, Vestibular Division, Medical Director, Balance and Vestibular Center, Massachusetts Eye and Ear, Professor of Otolaryngology–Head and Neck Surgery, Harvard Medical School
Recent Article
Prior Surgery No Barrier to Cochlear Implantation for Ménière's Disease
Mass Eye and Ear/Mass General Otolaryngology–Head and Neck Surgery
A teaching hospital of Harvard Medical School, Mass Eye and Ear/Massachusetts General Hospital combines the expertise of highly specialized ear, nose, and throat physicians, audiologists, speech-language pathologists and auxiliary health care professionals to provide care for patients with problems affecting the ear, nose, throat, head and neck areas. The department, which is led by Chief and Chair Mark A. Varvares, MD, FACS, is one of the largest otolaryngology–head and neck surgery (OHNS) departments in the country, with more than 70 physicians staffed at 15 locations in the greater Boston area.
