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Featured
Is Accelerated Infliximab Induction Beneficial for Severe Ulcerative Colitis?
While short-interval administration of infliximab was equally efficacious as standard administration for severe ulcerative colitis, a multicenter retrospective study has shown that a higher dose upon initiation reduced the risk of colectomy.
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Featured
Discovering the Role of C1orf106 in Patients with IBD
C1orf106 is a known susceptibility gene for inflammatory bowel disease, and now Massachusetts General researchers have identified its role: it "fine tunes" the integrity of the intestinal epithelial barrier.
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Featured
Obesity Tied to Risk of Diverticulosis
By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.
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Review: Fecal Incontinence in Older Adults
Trisha Pasricha, MD, and Kyle Staller, MD, MPH, of the Division of Gastroenterology, provide practical guidance to geriatricians and other primary care clinicians about managing fecal incontinence in older adults.
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Collagenous Colitis Associated with Increased Incidence, Severity of COVID-19
Hamed Khalili, MD, MPH, and colleagues have linked collagenous colitis to increased risk of severe COVID-19—and found that the association may be related in part to genetic factors.
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Very Few Older Adults Are Included in Trials of IBD Medications
Only 0.9% of patients in recent randomized, controlled trials of medications for inflammatory bowel disease were ≥65 years old, and for trials of biologic agents, the figure was 0.5%, Massachusetts General Hospital researchers determined based on the first systematic review of this issue.
Bowel Disease contributors
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Andrew T. Chan, MD, MPH
Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
Prior Antibiotics Linked to Increased Risk of New Diverticulitis in Older Adults
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Ashwin N. Ananthakrishnan, MBBS, MPH
Director, Crohn’s and Colitis Center
Recent Article
Very Few Older Adults Are Included in Trials of IBD Medications
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Hamed Khalili, MD, MPH
Gastroenterologist
Recent Article
Collagenous Colitis Associated with Increased Incidence, Severity of COVID-19
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Wenjie Ma, MBBS, ScD
Research Fellow
Recent Article
Anti-inflammatory Diet May Prevent, Treat Diverticulitis
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.
