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Featured
Is Accelerated Infliximab Induction Beneficial for Severe Ulcerative Colitis?
While short-interval administration of infliximab was equally efficacious as standard administration for severe ulcerative colitis, a multicenter retrospective study has shown that a higher dose upon initiation reduced the risk of colectomy.
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Featured
Discovering the Role of C1orf106 in Patients with IBD
C1orf106 is a known susceptibility gene for inflammatory bowel disease, and now Massachusetts General researchers have identified its role: it "fine tunes" the integrity of the intestinal epithelial barrier.
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Featured
Obesity Tied to Risk of Diverticulosis
By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.
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Advances in Diverticulitis Treatment and Prevention
In this video, Andrew T. Chan, MD, MPH, discusses advances in understanding the causes of diverticulitis and the significance of his team's research on disease prevention.
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Patient-Driven Consensus Effort Defines Ileoanal Pouch Syndrome
Surgeons at Massachusetts General Hospital helped lead an international, patient-driven consensus study that identified the functional outcomes patients consider important after pouch surgery—and defined "ileoanal pouch syndrome," a constellation of symptoms and consequences specific to having an ileoanal pouch.
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No Incremental Safety Risk Attributable to Anti-TNF Therapy in Older Patients with Ulcerative Colitis
By pooling data from four clinical trials, David Cheng, PhD, Kelly C. Cushing, and Ashwin N. Ananthakrishnan, MBBS, MPH, and colleagues found that ulcerative colitis patients who are ≥60 years old treated with tumor necrosis factor-α antagonists did not exhibit increased risk of serious adverse events attributable to the treatment.
Bowel Disease Contributors
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Andrew T. Chan, MD, MPH
Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
Advances in Diverticulitis Treatment and Prevention
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Ashwin N. Ananthakrishnan, MBBS, MPH
Director of the Crohn's and Colitis Center, Mass General, Associate Professor of Medicine, Harvard Medical School
Recent Article
Combining Immunomodulator With Vedolizumab or Ustekinumab Does Not Improve IBD Outcomes
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Hamed Khalili, MD, MPH
Gastroenterologist
Recent Article
Collagenous Colitis Associated with Increased Incidence, Severity of COVID-19
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Wenjie Ma, MBBS, ScD
Research Fellow
Recent Article
Anti-inflammatory Diet May Prevent, Treat Diverticulitis
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.
