TopicBowel Disease

Featured

Is Accelerated Infliximab Induction Beneficial for Severe Ulcerative Colitis?

While short-interval administration of infliximab was equally efficacious as standard administration for severe ulcerative colitis, a multicenter retrospective study has shown that a higher dose upon initiation reduced the risk of colectomy. 

Bowel Disease, Digestive Health

Journal March 1, 2019

Featured

Discovering the Role of C1orf106 in Patients with IBD

C1orf106 is a known susceptibility gene for inflammatory bowel disease, and now Massachusetts General researchers have identified its role: it "fine tunes" the integrity of the intestinal epithelial barrier.

Bowel Disease, Digestive Health

Journal March 15, 2019

Featured

Obesity Tied to Risk of Diverticulosis

By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.

Bowel Disease, Digestive Health, Obesity

Journal March 29, 2019

Identifying the Significance of Microbiome Diversity

The Center for the Study of IBD at Massachusetts General Hospital is leading research to understand how the microbiome influences health and disease.

Bowel Disease, Digestive Health

Article April 19, 2019

Hormone Replacement Therapy, Oral Contraceptives May Increase Risk of Microscopic Colitis

There's a new reason for women to minimize the use of menopausal hormone replacement therapy: Massachusetts General Hospital gastroenterologists have demonstrated an association between exogenous estrogen and the risk of microscopic colitis.

Bowel Disease, Digestive Health, Menopause

Journal March 22, 2019

BMI Linked to Diverticulitis in Women

Using data from the Nurses' Health Study, gastroenterologists at Massachusetts General Hospital found an independent association between BMI and risk of diverticulitis in women.

Bowel Disease, Digestive Health

Journal March 20, 2019