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Featured
Is Accelerated Infliximab Induction Beneficial for Severe Ulcerative Colitis?
While short-interval administration of infliximab was equally efficacious as standard administration for severe ulcerative colitis, a multicenter retrospective study has shown that a higher dose upon initiation reduced the risk of colectomy.
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Featured
Discovering the Role of C1orf106 in Patients with IBD
C1orf106 is a known susceptibility gene for inflammatory bowel disease, and now Massachusetts General researchers have identified its role: it "fine tunes" the integrity of the intestinal epithelial barrier.
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Featured
Obesity Tied to Risk of Diverticulosis
By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.
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No Link Between Gluten Intake, Digestive System Cancers in People Without Celiac Disease
By analyzing data from three large U.S. longitudinal cohorts, Massachusetts General Hospital researchers found individuals without celiac disease are unlikely to reduce their risk of digestive system cancers by following a low-gluten or gluten-free diet.
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Frailty Assessment May Be Useful for Risk Stratification of Older Adults With IBD
Bharati Kochar, MD, MS, and colleagues have demonstrated that among older adults with new-onset inflammatory bowel disease, a higher risk of frailty is associated with a three-fold higher risk of all-cause mortality and two-fold higher risk of all-cause hospitalization, even after accounting for comorbidities.
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Studies on the Age of Onset of Colorectal Cancer and IBD
Patients with a longer duration of inflammatory bowel disease (IBD) have higher cancer risk, but the exact operative approach and outcomes of these cancers has yet to be studied extensively. Robert Goldstone, MD, discusses his team's recent findings regarding the age of onset colorectal cancer in patients with IBD.
Bowel Disease Contributors
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Andrew T. Chan, MD, MPH
Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
Red Meat Consumption Increases Risk of Nonalcoholic Fatty Liver Disease in Women
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Ashwin N. Ananthakrishnan, MBBS, MPH
Director of the Crohn's and Colitis Center, Mass General, Associate Professor of Medicine, Harvard Medical School
Recent Article
Medicare Data Suggest Vedolizumab Safe, Effective in Older Adults with IBD
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Hamed Khalili, MD, MPH
Gastroenterologist | Internist
Recent Article
Frailty Assessment May Be Useful for Risk Stratification of Older Adults With IBD
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Wenjie Ma, MBBS, ScD
Research Fellow
Recent Article
Anti-inflammatory Diet May Prevent, Treat Diverticulitis
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.