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Featured
Is Accelerated Infliximab Induction Beneficial for Severe Ulcerative Colitis?
While short-interval administration of infliximab was equally efficacious as standard administration for severe ulcerative colitis, a multicenter retrospective study has shown that a higher dose upon initiation reduced the risk of colectomy.
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Featured
Discovering the Role of C1orf106 in Patients with IBD
C1orf106 is a known susceptibility gene for inflammatory bowel disease, and now Massachusetts General researchers have identified its role: it "fine tunes" the integrity of the intestinal epithelial barrier.
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Featured
Obesity Tied to Risk of Diverticulosis
By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.
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Medicare Data Suggest Vedolizumab Safe, Effective in Older Adults with IBD
Massachusetts General Hospital researchers have found that older adults with inflammatory bowel disease who initiate vedolizumab have a lower risk of infection-related hospitalization than those initiating a tumor necrosis factor inhibitor.
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Gluten Intake Does Not Influence Cognitive Function in People Without Celiac Disease
In a nationwide cohort of middle-aged women without celiac disease, Massachusetts General Hospital researchers found no evidence of a meaningful association between long-term gluten intake over two decades and subsequent performance on a validated cognitive battery.
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Diagnostic Yield of Endoscopy Is Low After Initial Diagnosis of IBS
Kyle Staller, MD, MPH, director of the Gastrointestinal Motility Laboratory, and colleagues determined that the diagnostic yield of colonoscopy and upper endoscopy for organic disease is low in patients with a first-time diagnosis of irritable bowel syndrome, although it increases with age.
Bowel Disease Contributors
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Andrew T. Chan, MD, MPH
Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
Medicare Data Suggest Vedolizumab Safe, Effective in Older Adults with IBD
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Ashwin N. Ananthakrishnan, MBBS, MPH
Director of the Crohn's and Colitis Center, Mass General, Associate Professor of Medicine, Harvard Medical School
Recent Article
Medicare Data Suggest Vedolizumab Safe, Effective in Older Adults with IBD
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Hamed Khalili, MD, MPH
Gastroenterologist
Recent Article
Collagenous Colitis Associated with Increased Incidence, Severity of COVID-19
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Wenjie Ma, MBBS, ScD
Research Fellow
Recent Article
Anti-inflammatory Diet May Prevent, Treat Diverticulitis
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.
