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Featured
Is Accelerated Infliximab Induction Beneficial for Severe Ulcerative Colitis?
While short-interval administration of infliximab was equally efficacious as standard administration for severe ulcerative colitis, a multicenter retrospective study has shown that a higher dose upon initiation reduced the risk of colectomy.
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Featured
Discovering the Role of C1orf106 in Patients with IBD
C1orf106 is a known susceptibility gene for inflammatory bowel disease, and now Massachusetts General researchers have identified its role: it "fine tunes" the integrity of the intestinal epithelial barrier.
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Featured
Obesity Tied to Risk of Diverticulosis
By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.
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Researchers Chart the Course of Severe Checkpoint Inhibitor-related Colitis
Massachusetts General Hospital researchers have charted the course of severe checkpoint inhibitor–related colitis, including the fact that it usually develops within three months, and that half of the patients require second-line immunosuppression.
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Research Highlights Intestinal Dysbiosis as Defining Feature of Microscopic Colitis
Intestinal dysbiosis appears to be the defining feature of the gut microbiome in microscopic colitis.
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Dual Immunosuppression Linked to Better Outcomes in Complicated Crohn's Disease
In a prospective multicenter cohort, combination therapy with a TNF inhibitor and an immunomodulator was associated with decreased rates of hospitalization, surgery and other adverse outcomes in patients with complicated Crohn's disease.
Bowel Disease contributors
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Andrew T. Chan, MD, MPH
Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine
Recent Article
New Female-centric Research Provides Dietary Guidance for Preventing Diverticulitis
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Ashwin N. Ananthakrishnan, MBBS, MPH
Director, Crohn’s and Colitis Center
Recent Article
CT Identifies Which Patients Hospitalized for Ulcerative Colitis Need Rescue Therapy
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Hamed Khalili, MD, MPH
Gastroenterologist
Recent Article
Research Highlights Intestinal Dysbiosis as Defining Feature of Microscopic Colitis
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Wenjie Ma, MBBS, ScD
Research Fellow
Recent Article
New Female-centric Research Provides Dietary Guidance for Preventing Diverticulitis
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.
