Posts by Hamed Khalili, MD, MPH
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Initiating Oral Contraception Does Not Change Gut Microbiome in Healthy Women
Xinwei Hua, PhD, MPH, Hamed Khalili, MD, MPH, and colleagues found that oral contraception initiation was not associated with a significant change in the gut microbiome composition in healthy women, although the relative abundance of certain metabolic pathways increased.
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Frailty Assessment May Be Useful for Risk Stratification of Older Adults With IBD
Bharati Kochar, MD, MS, and colleagues have demonstrated that among older adults with new-onset inflammatory bowel disease, a higher risk of frailty is associated with a three-fold higher risk of all-cause mortality and two-fold higher risk of all-cause hospitalization, even after accounting for comorbidities.
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Collagenous Colitis Associated with Increased Incidence, Severity of COVID-19
Hamed Khalili, MD, MPH, and colleagues have linked collagenous colitis to increased risk of severe COVID-19—and found that the association may be related in part to genetic factors.
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Greater Fruit and Vegetable Intake Linked to Lower Risk of Diverticulosis
Data from a Mass General registry support a significant association between fruit and vegetable consumption and subsequent risk of diverticulosis.
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Patients with Microscopic Colitis Are at Increased Risk of Inflammatory Bowel Disease
Based on histologic data and more than 20 years of follow-up, a nationwide registry study has demonstrated that patients with microscopic colitis are substantially more likely than those without to develop inflammatory bowel disease.
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Obesity and Weight Gain Since Early Adulthood Are Associated with a Lower Risk of Microscopic Colitis
Microscopic colitis differs strikingly from many other immune- and metabolic-related disorders, including other forms of inflammatory bowel disease, in that its incidence is inversely associated with obesity and weight gain since early adulthood.
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Research Highlights Intestinal Dysbiosis as Defining Feature of Microscopic Colitis
Intestinal dysbiosis appears to be the defining feature of the gut microbiome in microscopic colitis.
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Obesity Tied to Risk of Diverticulosis
By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.
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Hormone Replacement Therapy, Oral Contraceptives May Increase Risk of Microscopic Colitis
There's a new reason for women to minimize the use of menopausal hormone replacement therapy: Massachusetts General Hospital gastroenterologists have demonstrated an association between exogenous estrogen and the risk of microscopic colitis.
Biography
Hamed Khalili, MD, MPH, is a gastroenterologist in the Clinical and Translational Epidemiology Unit at Massachusetts General Hospital and an associate professor of medicine at Harvard Medical School.
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.