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Featured
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
Massachusetts General Hospital and McClean Hospital researchers take significant steps towards proving the safety and efficacy of dopaminergic neuron implantation to treat Parkinson's disease.
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Featured
First-In-Human Therapy with Stem Cell–derived Dopaminergic Progenitor Cells for Parkinson's Disease
Mass General researchers report substantial clinical improvement in a patient with Parkinson's disease after they implanted midbrain dopaminergic progenitor cells that they differentiated in vitro from autologous induced pluripotent stem cells.
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Featured
Collaboration in Developing New Cell Therapy
In this video, Bob S. Carter, MD, PhD, Kwang-Soo Kim, PhD, Todd M. Herrington, MD, PhD, and Jeffrey S. Schweitzer, MD, PhD, discuss their cross-disciplinary and multi-institutional collaboration to develop this new therapy.
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Novel Genetic Loci Linked to Cognitive Decline in Parkinson's Disease
As part of an international consortium, Massachusetts General Hospital neurologists helped identify three genetic loci, and confirm two others, that influence time to progression to dementia in Parkinson's disease, and devised a polygenic score that predicts which PD patients are likely to rapidly develop dementia.
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The Precision and Safety of Deep Brain Stimulation
Mark Richardson, MD, PhD, director of Functional Neurosurgery in the Department of Neurosurgery, discusses the evolution and successful use of deep brain stimulation to treat those with Parkinson's disease and dystonia, and the use of robotics to enhance surgical outcomes.
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Location of Deep Brain Stimulation in Parkinson's Disease Patients Affects Postoperative Voice Quality
In patients with Parkinson's disease who underwent deep brain stimulation, improvements in perceptual, acoustic and aerodynamic voice measures were likely if electrodes were placed in the anterior sensorimotor region of the left subthalamic nucleus.
Parkinson's Disease Contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Review: Challenges in Discovering Extracellular Vesicle–based Cancer Biomarkers
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Cromolyn Sodium Provides Neuroprotection in Animal Model of ALS
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Jeffrey S. Schweitzer, MD, PhD
Neurosurgeon
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Michael D. Fox, MD, PhD
Associate Professor of Neurology, Harvard Medical School, Director, Laboratory for Brain Network Imaging and Modulation, Harvard Medical School, Assistant Neuroscientist, Massachusetts General Hospital
Recent Article
Lesion Locations Causing Cervical Dystonia Are Part of a Common Brain Network -
Robert (Mark) Richardson, MD, PhD
Director of Functional Neurosurgery, Massachusetts General Hospital
Recent Article
Case Report: Responsive Neurostimulation for Treatment of Super-Refractory Status Epilepticus
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Todd M. Herrington, MD, PhD
Director, Deep Brain Stimulation Program, Massachusetts General Hospital
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Ziv Williams, MD
Associate Professor in Neurosurgery
Recent Article
Single Neurons Identified That Support Social Reasoning
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
