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Featured
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
Massachusetts General Hospital and McClean Hospital researchers take significant steps towards proving the safety and efficacy of dopaminergic neuron implantation to treat Parkinson's disease.
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Featured
First-In-Human Therapy with Stem Cell–derived Dopaminergic Progenitor Cells for Parkinson's Disease
Mass General researchers report substantial clinical improvement in a patient with Parkinson's disease after they implanted midbrain dopaminergic progenitor cells that they differentiated in vitro from autologous induced pluripotent stem cells.
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Featured
Collaboration in Developing New Cell Therapy
In this video, Bob S. Carter, MD, PhD, Kwang-Soo Kim, PhD, Todd M. Herrington, MD, PhD, and Jeffrey S. Schweitzer, MD, PhD, discuss their cross-disciplinary and multi-institutional collaboration to develop this new therapy.
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Functional MRI Shows How Parkinson's Disease Disrupts Neuronal Circuits
Radiology researchers Silvia Basaia and Jorge Sepulcre, MD, PhD, DMSc, and colleagues characterized large-scale brain propagation pathways associated with α-synuclein neural protein spreading and identified different patterns of functional connectivity disruptions in patients at different stages of Parkinson's disease.
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Review: Understanding Neuroimaging–Genetic Intersections in the Human Brain
Ibai Diez, PhD, and Jorge Sepulcre, PhD, DMSc, MD, of the Gordon Center for Medical Imaging, explain how neuroimaging findings are being combined with genetic data—research that might lead to disease-modifying therapies for neurodegenerative diseases.
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Novel Genetic Loci Linked to Cognitive Decline in Parkinson's Disease
As part of an international consortium, Massachusetts General Hospital neurologists helped identify three genetic loci, and confirm two others, that influence time to progression to dementia in Parkinson's disease, and devised a polygenic score that predicts which PD patients are likely to rapidly develop dementia.
Parkinson's Disease Contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
The Future of Neurosurgery and Neuroscience at Mass General: Q&A With Bob S. Carter, MD, PhD
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Novel Target Identified for Treatment of ALS
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Jeffrey S. Schweitzer, MD, PhD
Neurosurgeon
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Michael D. Fox, MD, PhD
Associate Professor of Neurology, Harvard Medical School, Director, Laboratory for Brain Network Imaging and Modulation, Harvard Medical School, Assistant Neuroscientist, Massachusetts General Hospital
Recent Article
Lesion Locations Causing Cervical Dystonia Are Part of a Common Brain Network -
Robert (Mark) Richardson, MD, PhD
Director of Functional Neurosurgery, Massachusetts General Hospital
Recent Article
Barques Are Generated in Posterior Human Hippocampus
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Todd M. Herrington, MD, PhD
Director, Deep Brain Stimulation Program, Massachusetts General Hospital
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Ziv Williams, MD
Neurosurgeon, Department of Neurosurgery, Massachusetts General Hospital, Associate Professor in Neurosurgery, Harvard Medical School
Recent Article
Basic Rules Identified for Therapeutic Intracranial Stimulation of the Human Brain
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.