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Featured
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
Massachusetts General Hospital and McClean Hospital researchers take significant steps towards proving the safety and efficacy of dopaminergic neuron implantation to treat Parkinson's disease.
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Featured
First-In-Human Therapy with Stem Cell–derived Dopaminergic Progenitor Cells for Parkinson's Disease
Mass General researchers report substantial clinical improvement in a patient with Parkinson's disease after they implanted midbrain dopaminergic progenitor cells that they differentiated in vitro from autologous induced pluripotent stem cells.
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Featured
Collaboration in Developing New Cell Therapy
In this video, Bob S. Carter, MD, PhD, Kwang-Soo Kim, PhD, Todd M. Herrington, MD, PhD, and Jeffrey S. Schweitzer, MD, PhD, discuss their cross-disciplinary and multi-institutional collaboration to develop this new therapy.
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Location of Deep Brain Stimulation in Parkinson's Disease Patients Affects Postoperative Voice Quality
In patients with Parkinson's disease who underwent deep brain stimulation, improvements in perceptual, acoustic and aerodynamic voice measures were likely if electrodes were placed in the anterior sensorimotor region of the left subthalamic nucleus.
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Using MRI to Deliver Gene Therapy for Parkinson's Disease
Massachusetts General Hospital is launching a trial of a therapeutic enzyme for Parkinson's disease using intraoperative MRI for more accurate drug delivery in the brain.
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Timing of Activity in the Basal Ganglia Is More Important to Movement than Firing Rates
Intraoperative electrophysiological data from patients with Parkinson's disease show that just prior to movement on a handgrip task, there was elevated subthalamic nucleus spike-to-cortical gamma phase coupling that preceded faster reaction times.
Parkinsons Disease contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Gene Fusions Detected in Plasma of Glioblastoma Patients, Suggesting New Approach to Liquid Biopsy
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Cromolyn Sodium Provides Neuroprotection in Animal Model of ALS
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Jeffrey S. Schweitzer, MD, PhD
Neurosurgeon
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Michael D. Fox, MD, PhD
Associate Professor of Neurology, Harvard Medical School, Director, Laboratory for Brain Network Imaging and Modulation, Harvard Medical School, Assistant Neuroscientist, Massachusetts General Hospital
Recent Article
Lesion Locations Causing Cervical Dystonia Are Part of a Common Brain Network -
Robert (Mark) Richardson, MD, PhD
Director of Functional Neurosurgery, Massachusetts General Hospital
Recent Article
Location of Deep Brain Stimulation in Parkinson's Disease Patients Affects Postoperative Voice Quality
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Todd M. Herrington, MD, PhD
Director, Deep Brain Stimulation Program, Massachusetts General Hospital
Recent Article
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
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Ziv Williams, MD
Associate Professor in Neurosurgery
Recent Article
Spine Surgeon Specialty Does Not Influence Short-term Outcomes of Percutaneous Kyphoplasty
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
