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Featured
Patient-derived Dopamine Neurons Show Promise in Parkinson's Treatment
Massachusetts General Hospital and McClean Hospital researchers take significant steps towards proving the safety and efficacy of dopaminergic neuron implantation to treat Parkinson's disease.
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Featured
First-In-Human Therapy with Stem Cell–derived Dopaminergic Progenitor Cells for Parkinson's Disease
Mass General researchers report substantial clinical improvement in a patient with Parkinson's disease after they implanted midbrain dopaminergic progenitor cells that they differentiated in vitro from autologous induced pluripotent stem cells.
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Featured
Collaboration in Developing New Cell Therapy
In this video, Bob S. Carter, MD, PhD, Kwang-Soo Kim, PhD, Todd M. Herrington, MD, PhD, and Jeffrey S. Schweitzer, MD, PhD, discuss their cross-disciplinary and multi-institutional collaboration to develop this new therapy.
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Co-transplantation of Regulatory T Cells Improves Cell Replacement Therapy for Parkinson's Disease
Research at Massachusetts General Hospital suggests a novel strategy for enhancing the efficacy and safety of cell replacement therapy in the nervous system: co-transplantation of dopamine progenitor cells with regulatory T cells to modulate the host immune response triggered by needle trauma.
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Toward a Precision Medicine Approach to Deep Brain Stimulation
Victoria Peterson, PhD, Mark Richardson, MD, PhD, and colleagues showed that applying spatial filters improves machine-learning analysis of movement-related oscillations on invasive cortical and subcortical recordings, an important step toward providing individualized therapy with adaptive deep brain stimulation.
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Functional MRI Shows How Parkinson's Disease Disrupts Neuronal Circuits
Radiology researchers Silvia Basaia and Jorge Sepulcre, MD, PhD, DMSc, and colleagues characterized large-scale brain propagation pathways associated with α-synuclein neural protein spreading and identified different patterns of functional connectivity disruptions in patients at different stages of Parkinson's disease.
Parkinson's Disease Contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Co-transplantation of Regulatory T Cells Improves Cell Replacement Therapy for Parkinson's Disease
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Novel Target Identified for Treatment of ALS
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Jeffrey S. Schweitzer, MD, PhD
Neurosurgeon
Recent Article
Co-transplantation of Regulatory T Cells Improves Cell Replacement Therapy for Parkinson's Disease
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Michael D. Fox, MD, PhD
Associate Professor of Neurology, Harvard Medical School, Director, Laboratory for Brain Network Imaging and Modulation, Harvard Medical School, Assistant Neuroscientist, Massachusetts General Hospital
Recent Article
Lesion Locations Causing Cervical Dystonia Are Part of a Common Brain Network -
Robert (Mark) Richardson, MD, PhD
Director of Functional Neurosurgery, Massachusetts General Hospital
Recent Article
Intracranial Stereo-EEG Resolves Discordant Clinical vs. Neuroimaging Findings in Patient With Tonic–Clonic Seizures
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Todd M. Herrington, MD, PhD
Director, Deep Brain Stimulation Program, Massachusetts General Hospital
Recent Article
Co-transplantation of Regulatory T Cells Improves Cell Replacement Therapy for Parkinson's Disease
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Ziv Williams, MD
Neurosurgeon, Department of Neurosurgery, Massachusetts General Hospital, Associate Professor in Neurosurgery, Harvard Medical School
Recent Article
Interim Safety Profile From the Feasibility Study of the BrainGate Neural Interface System
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.