Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Neuroscience
New Website Allows Provider Consultations for Patients With Restless Leg Syndrome
A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives.
Featured In Otolaryngology
The Toth Center: New Leadership, Novel Innovations
Scientists are working towards new, innovative approaches to faster and more accurate diagnoses, less invasive treatments, predictive medicine, and more. With new leadership and collaborations, the Toth Center at Mass Eye and Ear is making great headway for the future of head and neck cancer care.
Featured In Orthopaedics
First AI Model Developed for Diagnosis of Hip Dysplasia From Plain Radiographs
Martin Magnéli, MD, PhD, Kartik Varadarajan, PhD, and colleagues have developed two convolutional neural networks that can read plain radiographs and classify hips as dysplastic or non-dysplastic with 83% to 92% accuracy, and detect the severity of hip dysplasia based on the Crowe or Hartofilakidis classifications.
Featured In Oncology
Revolutionizing Cancer Immunotherapy for Melanoma and Beyond
Researchers at Massachusetts General Hospital won a Breakthrough Award to enhance personalized approaches to immunotherapy for metastatic melanoma.
Featured In OB/GYN
Single-Step Blastocyst Warming Validated, Saves Time Without Compromising Outcomes
Victoria S. Jiang, MD, Charles L. Bormann, PhD, and colleagues found that compared with standard blastocyst warming, a simpler protocol that removes at least 15 minutes from warming time yields similar rates of implantation, clinical pregnancy, spontaneous abortion, and live birth as well as similar birth weight.
The Latest Digestive Health Advances
Case Series: Tofacitinib Is Effective in Treating Refractory Immune Checkpoint Inhibitor Hepatitis
Ryan J. Sullivan, MD, Michael L. Dougan, MD, PhD, and colleagues have reported the first three cases of using a Janus kinase (JAK) inhibitor to treat hepatitis associated with immune checkpoint inhibitor therapy. All patients showed excellent response to tofacitinib, although their oncologic outcomes varied.
Healthcare–related Transportation Insecurity Is a Critical Social Risk Factor in Chronic Liver Disease
Nneka N. Ufere, MD, MSCE, Marina Serper, MD, MS, and colleagues found using nationwide U.S. data that 6% of patients with chronic liver disease report healthcare–related transportation insecurity, which about doubled the risk of mortality even after adjustment for income and other social risk factors.
Contributing Physicians
Ashwin N. Ananthakrishnan, MBBS, MPH
Director of the Crohn's and Colitis Center, Division of Gastroenterology, Mass General, Associate Professor of Medicine, Harvard Medical School
Ramnik Joseph Xavier, MD, PhD
Director, Center for the Study of Inflammatory Bowel Disease, Kurt J. Isselbacher Professor of Medicine in the Field of Gastroenterology, Harvard Medical School
Advances Specialties
Neuroscience
Single-Neuron Recordings Show How the Brain Plans Speech
Using single-neuron recordings, Massachusetts General Hospital researchers have discovered how the brain forms words before an individual speaks. Such recordings might be useful for developing synthetic speech prostheses or augmenting other approaches that benefit patients with neurological disorders.
Pulmonary and Critical Care
Transforming the Future of Lung Transplantation by Improving Access and Outcomes
Physicians at Massachusetts General Hospital are maximizing opportunities for lung transplants by capitalizing on groundbreaking research and technology.
Urology
Multiparametric MRI Is Often False-Negative for Clinically Significant Prostate Cancer
Chin-Lee Wu, MD, PhD, Douglas M. Dahl, MD, and colleagues found that 15% of patients who had negative prostate multiparametric MRI (mpMRI) were diagnosed by 20-core standard template biopsy as having clinically significant prostate cancer. They recommend considering standard biopsy regardless of negative mpMRI.
May 31, 2024 - June 4, 2024
Conference: ASCO 2024 Annual Meeting
Leaders from the Mass General Cancer Center will present groundbreaking cancer research at this year’s ASCO 2024 Annual Meeting, held May 31 – June 4, 2024, both in-person in Chicago, IL, and virtually.
May 16-19, 2024
Conference: Heart Rhythm 2024
Massachusetts General Hospital faculty will join the global electrophysiology community at Heart Rhythm 2024, an annual meeting and educational program hosted by the Heart Rhythm Society on May 16 - 19, 2024 in Boston, MA.
