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Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.

Featured In Neuroscience

Massachusetts General Hospital physician-scientist Patricia Musolino, MD, PhD, was a key investigator in a clinical trial that led to the first FDA-approved gene therapy for a cerebral disease. Her research is focused on studying rare genetic disorders to develop approaches that may lead to gene therapy treatments.

Featured In Cardiovascular

A pioneering Massachusetts General Hospital clinical care, research, and education program aims to improve outcomes from cardiovascular disease in women.

Featured In Orthopaedics

Massachusetts General Hospital orthopedic surgeons have developed a rat model in which gait and weightbearing are markers of recovery after repair of tibia fracture. Their long-term aim is to use the model to compare locally non-opioid analgesics to current pain management methods for long-bone fracture.

Featured In Research and Innovation

The Comprehensive Sickle Cell Disease Treatment Center at Massachusetts General Hospital will serve as an authorized treatment center for an FDA-approved gene therapy for sickle cell disease.

Featured In Oncology

Researchers at Massachusetts General Hospital are developing computation models capable of increasing the precision of targeted delivery of radiotherapy to liver tumors.

The Latest Ophthalmology Advances

This year, Mass Eye and Ear is celebrating its 200th anniversary. To kick things off, we are highlighting some of the ophthalmology department’s most significant achievements in patient care, research, and education.

Elizabeth J. Rossin, MD, PhD, and colleagues report on seven individuals who sustained severe, sometimes blinding open globe injuries when they attempted to repair a garage door and a spring dislodged at high velocity.

Contributing Physicians

Chief, Ophthalmology Department, Massachusetts General Hospital, Chief, Ophthalmology Department, Mass Eye and Ear, Ophthalmologist-in-Chief, Brigham and Women’s Hospital

Assistant Professor of Ophthalmology, Harvard Medical School, Assistant Scientist, Mass Eye and Ear

Advances Specialties

Digestive Health

Shuji Ogino, MD, PhD, Mingyang Song, MBBS, ScD, and colleagues leveraged data from two large, prospective U.S. studies that showed the use of vitamin C after diagnosis of colorectal cancer with KRAS or BRAF mutations was associated with a 26% reduction in the risk of disease-specific mortality.


In 2021, a randomized controlled trial showed heated yoga outperformed a waitlist control in a group of women with mild-to-moderate depression. Researchers at Massachusetts General Hospital have extended the findings to a larger, mixed-gender, and more severely depressed population.

Rheumatology, Allergy and Immunology

A 49-year-old male presented to Massachusetts General Hospital, found to have new heart failure with a reduced ejection fraction and pericardial effusion. Testing revealed elevated cytomegalovirus (CMV) viral load, so the Pathways Service investigated how a previously immunocompetent patient developed CMV reactivation.

Education & Training Opportunities

February 10-14, 2024

The Society for Maternal-Fetal Medicine's Annual Meeting, The Pregnancy Meeting™, is the premier event for cutting-edge science in obstetrics where participants can connect with colleagues in maternal-fetal medicine. Learn about the research presented by the Department of Obstetrics and Gynecology at Massachusetts General Hospital.

February 12-16, 2024

Specialists from the Massachusetts General Hospital Department of Orthopaedic Surgery will present on leading research and innovative treatment approaches at the American Academy of Orthopaedic Surgeons 2024 Annual Meeting.