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Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.

Featured In Pulmonary and Critical Care

Massachusetts General Hospital physician-scientists are investigating ways to personalize medicine in the ICU, including research around alveolar epithelial glycocalyx function.

Featured In Otolaryngology

A new study from Mass Eye and Ear has proven the safety and efficacy of using hypoglossal nerve stimulation to treat obstructive sleep apnea in children with Down syndrome—and has uncovered exciting new clues on the treatment's impact on neurocognition.

Featured In Cardiovascular

Massachusetts General Hospital research is driving improved results in preclinical xenotransplantation models, paving the way for future human clinical trials.

Featured In Orthopaedics

Courtesy of AAOS Orthopaedic Video Theater, Mass General Brigham Sports Medicine surgeon Peter Asnis, MD, performs a femoral tunnel bone-dowel allograft grafting during a revision ACL reconstruction.

Featured In Neuroscience

Gwang-Won Kim, PhD, Maurizio Fava, MD, Daphne J. Holt, MD, PhD, and colleagues published evidence that reduced frontal pole size and reduced functional connectivity between the frontal pole and the inferior frontal cortex are markers of elevated suicidality in young adults.

The Latest OB/GYN Advances

Youngwu Kim, MD, Emily Von Bargen, DO, and colleagues found that of 169 stress-continent women who underwent minimally invasive sacrocolpopexy, 30 (18%) developed stress urinary incontinence (SUI). An existing calculator for determining the risk of postoperative de novo SUI performed moderately well in the cohort.

Massachusetts General Hospital researchers found in a nationwide study that contrary to guidelines, 34% of eligible patients with early-stage vulvar cancer did not undergo lymph node evaluation. Among patients 80 and older, the figure was 49%, even though withholding lymph node assessment did not improve survival.

Contributing Physicians

Director, Gynecology Oncology, Gynecologic Oncology Clerkship, Co-director, MGH Women's Global Health

Chief Medical Officer, Massachusetts General Physicians Organization and Massachusetts General Hospital, Gynecologic Oncologist, Department of Obstetrics and Gynecology, Clinician, Center for Gynecologic Oncology, Mass General Cancer Center

Marcela G. del Carmen, MD

Advances Specialties

Geriatrics and Palliative Care

Emily L. Aaronson, MD, MPH, Jeffrey L. Greenwald, MD, and colleagues conducted a randomized pilot trial in which emergency department social workers had serious illness conversations with 66% of older adults with potential palliative care needs—on top of their usual duties—and 77% of patients appreciated the talk.

Pulmonary and Critical Care

Massachusetts General Hospital performs advanced transcatheter pulmonary valve replacement (TPVR) to immediately relieve pulmonary regurgitation without open-heart surgery.


Through careful unraveling of the cellular and molecular landscape of prostate cancer, Massachusetts General Hospital researchers observed a highly immune-suppressive tumor microenvironment with a pattern of angiogenic gene expression, findings that will help identify targets amenable to therapeutic interventions.

Education & Training Opportunities

May 12, 2023

The Midlife Women's Health 2023 course is led by a multidisciplinary group of experts from Massachusetts General Hospital who will present on midlife mood disorders, cancer survivorship, skin health, recurrent UTIs, obesity, cardiovascular health, transgender medicine, early menopause, menopausal hormone therapy, and novel non-hormonal options for hot flashes.

March 22-25, 2023

On March 22 - 25, 2023, the Society of Surgical Oncology hosts its International Conference on Surgical Cancer Care in Boston, MA. Colleagues from the Mass General Cancer Center will present their latest research at the conference.

Clinical Trials

In Neuroscience

The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.

In Cardiovascular

We are seeking individuals who self-identify as having high stress to participate in a randomized study using a mindfulness-based, stress-reduction intervention and PET-MR imaging.