Posts by Saumya Das, MD, PhD
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SGK1 Is a Potential New Target to Prevent Obesity-related Atrial Fibrillation
Aneesh Bapat, MD, David Milan, MD, Saumya Das, MD, PhD, and colleagues demonstrated in a mouse model that genetic inhibition of serum glucocorticoid kinase 1 (SGK1) prevents some of the atrial fibrillation risk associated with diet-induced obesity, suggesting SGK1 is an attractive potential therapeutic target.
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Exercise Training Recommended for Depressed Patients with Heart Failure
Researchers at Massachusetts General Hospital have conducted the first network meta-analysis that examines three common treatments for depression in patients with heart failure.
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Specific microRNAs Linked to Post-MI Remodeling
By studying a large cohort of patients who had cardiac MRI after myocardial infarction, scientists at Massachusetts General have demonstrated the association of microRNAs with specific features of left ventricular remodeling, suggesting it may someday be possible to pinpoint early biomarkers of heart failure.
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New Strategies for Heart Failure Patients Improves Outcomes
One-third of heart failure patients do not respond to cardiac resynchronization therapy (CRT) | A coordinated care approach at Mass General for heart failure patients improves outcomes.
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Can Non-Coding RNAs Serve as Biomarkers for Cardiovascular Disease?
Non-coding RNAs were once considered of little use. Now a team of researchers led by Saumya Das, MD, PhD at Mass General are working to identify RNA prognostic biomarkers for cardiovascular diseases.
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Manipulating Autophagy in the Heart Inhibits Stress-Induced Pathological Cardiac Hypertrophy
Researchers from Massachusetts General Hospital set out to find what drives the “good stress” and “bad stress” responses in the heart. In preliminary in vivo studies, they found that the answer may lie in the gene known as DNA damage-inducible transcript 4-like (DDiT4L)
Biography
After finishing college, medical school and graduate school at Harvard Medical School, I graduated with an MD-PhD in 2000. I completed my training in internal medicine, cardiovascular sciences and clinical electrophysiology at Massachusetts General Hospital, where I am was on staff from 2007-2011. I was then at Beth Israel Deaconess Medical Center as the Co-director of the Cardiovascular Genetics Center and ran an active research program on RNA biomarkers for heart failure and arrhythmias. I was recruited back to MGH and am the co-director of the Resynchronization and Advanced Cardiac Therapeutics Program. I am seeing general cardiac arrhythmia patients, with a special emphasis on patients with inherited arrhythmias, cardiomyopathies and sudden cardiac death. My research focuses on understanding mechanisms of arrhythmias in heart failure, discovering new tests to provide better identification of patients at risk of developing heart failure or arrhythmias, and uncovering new therapies to treat heart failure. I see patients with a range of cardiac arrhythmia problems, including heart failure, supraventricular arrhythmias and sudden cardiac death.
Cardiovascular Care at Mass General
At Mass General, our world-class physicians and nurses specialize in specific forms of both heart and vascular disease, and work closely together to offer leading treatments and preventive care for cardiovascular conditions.