Advances in Motion provides health care professionals with information about latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Cardiovascular
Study Shows Sedentary Time Increases Cardiovascular Disease
Sedentary time negatively impacts heart health regardless of whether a person follows exercise guidelines.
Featured In Neuroscience
From Stroke Detection to Cancer Screening: AI Tools Advancing Imaging Efficiency
Mass General Brigham has developed initiatives for artificial intelligence (AI) governance and inclusion of medical expertise to address an influx of AI technology in medical imaging.
Featured In Oncology
Optimizing Treatment Alternatives for Relapsed/Refractory T Cell Lymphomas
Massachusetts General Hospital leads the global PETAL consortium to advance the understanding and treatment of newly diagnosed and relapsed/refractory T cell lymphomas.
Featured In Rheumatology, Allergy and Immunology
Innovations in Allergy Immunotherapy: Perspectives From Sarita Patil, MD
Food allergies represent a growing public health concern, affecting millions of individuals globally and posing significant clinical and quality-of-life challenges. However, their efficacy remains inconsistent, with only a subset of patients achieving long-term tolerance.
Featured In Ophthalmology
Non-invasive OCTA Imaging Biomarker Tied to Neovascular Glaucoma in Patients With Proliferative Diabetic Retinopathy
John B. Miller, MD, Edward S. Lu, MD, and colleagues found retinal ischemia on widefield swept-source optical coherence tomography angiography was associated with 13-fold increased odds of neovascular glaucoma, a vision-threatening complication in patients with proliferative diabetic retinopathy.
The Latest Oncology Advances
Ultrasound Can Identify Subclinical Musculoskeletal Toxicity of Cancer Checkpoint Inhibitor Therapy
Massachusetts General Hospital physicians found that among 34 patients with new musculoskeletal symptoms during checkpoint inhibitor therapy, ultrasound identified inflammation in 10 of 14 patients without clinically evident synovitis and in all seven whose synovial fluid cell counts were in the non-inflammatory range.
Video Visits Equivalent to In-Person Visits for Early Palliative Care of Patients With Advanced Cancer
Jennifer Temel, MD, Joseph Greer, PhD, Vicki Jackson, MD, and colleagues in the REACH PC trial found patients with advanced lung cancer have similar quality of life, mood, coping skills, and understanding of prognosis and treatment goals whether they receive early palliative care via video or in-person visits.
Contributing Physicians
Genevieve M. Boland, MD, PhD
Vice Chair of Research, Department of Surgery, Massachusetts General Hospital, Section Head, Melanoma and Sarcoma Surgery Programs, Surgical Director, Termeer Center for Targeted Therapies, Mass General Cancer Center
Marcela V. Maus, MD, PhD
Director, Cellular Immunotherapy Program, Mass General Cancer Center, Associate Professor of Medicine, Harvard Medical School
Advances Specialties
Cardiovascular
ADVANCE Grand Rounds: Q&A With Dr. Colleen Harrington
Mass General's Corrigan Women's Heart Health Program is formally launching the ADVANCE Grand Rounds series in September 2025. This monthly program aims to educate healthcare professionals about women's cardiovascular health with the goal of improving cardiovascular outcomes for all women.
Neuroscience
Disrupted Cortico-Striato-Thalamo-Cortical Circuitry May Underlie Sleep Disturbances in the "Tourette Triad"
Erica Greenberg, MD and colleagues found evidence in the medical literature of a bidirectional relationship between "the Tourette triad" and sleep symptoms: sleep problems in individuals with tics, OCD, ADHD may in part be caused by the same shared impaired functional connectivity in brain circuitry that leads to symptoms of OCD, tic disorders, and ADHD.
Orthopaedics
Clinical Outcomes Are Comparable With Robotic and Manual Total Hip Arthroplasty
Christopher M. Melnic, MD, and colleagues found that patients undergoing robotic total hip arthroplasty were similar to those who had manual surgery in their rates of achieving the minimal clinically important difference for improvement on questionnaires about physical and mental function.
May 9, 2025
Conference: Midlife Women's Health 2025: A Multidisciplinary Approach to Care
The Midlife Women's Health 2025 course is led by a multidisciplinary group of experts from Massachusetts General Hospital who will present on the evaluation and management of osteoporosis, gastrointestinal malignancy, stress, obesity, substance use disorder, anxiety, sexual dysfunction, breast cancer, and menopausal hormone therapy to assist clinicians in caring for their midlife patients.
Brain mechanisms of vagus nerve stimulation and stress reduction training for migraine
The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.
Multimodal profiling of stress-induced immune reprogramming in cardiovascular participants
The purpose of this research study is to learn about the effects of stress on the brain and disease of the heart and blood vessels (cardiovascular disease or CVD).
