Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Neuroscience
New Website Allows Provider Consultations for Patients With Restless Leg Syndrome
A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives.
Featured In Oncology
Revolutionizing Cancer Immunotherapy for Melanoma and Beyond
Researchers at Massachusetts General Hospital won a Breakthrough Award to enhance personalized approaches to immunotherapy for metastatic melanoma.
Featured In Endocrinology
Continuous Glucose Monitoring Predicts Long-term Nutritional Outcomes in Adults With Cystic Fibrosis
Melissa S. Putman, MD, and colleagues correlated findings on continuous glucose monitoring with a decline in body weight and a decline in body mass index over one year in adults with cystic fibrosis. Their data also suggest advanced glycation end products may represent a useful marker in this population.
Featured In Digestive Health
AGA Guideline Makes the Case for Biomarkers in Managing Crohn's Disease
Ashwin Ananthakrishnan, MD, discusses the AGA guideline's key recommendations for managing Crohn's disease and the evolving role of biomarkers in these treatments.
Featured In Otolaryngology
Cochlear Organoids Shed Light on Hair Cell Regeneration for Hearing Loss Treatment
Albert Edge, PhD, and colleagues have developed murine cochlear organoids that show how sensory epithelial progenitor cells differentiate into hair cells, a potential step toward developing regenerative therapies for human hearing loss.
The Latest Cardiovascular Advances
Newly Identified Genes Linked to Coronary Artery Calcification
Hanna Barnes, MD, Christian Lino Cardenas, PhD, PharmD, Rajeev Malhotra, MD, and colleagues add to the understanding of the genetic basis of coronary artery calcification by identifying 43 candidate genes at 11 chromosomal locations and demonstrating effects on cellular reprogramming leading to vascular calcification.
Pulsed Field Ablation Noninferior to Conventional Thermal Ablation for Paroxysmal Atrial Fibrillation
Moussa Mansour, MD, and colleagues showed in the ADVENT registrational trial of the Farapulse system that among patients with atrial fibrillation, pulsed-field ablation was noninferior to conventional thermal ablation with respect to efficacy and device- and procedure-related serious adverse events within one year.
Advances Specialties
OB/GYN
Single-Step Blastocyst Warming Validated, Saves Time Without Compromising Outcomes
Victoria S. Jiang, MD, Charles L. Bormann, PhD, and colleagues found that compared with standard blastocyst warming, a simpler protocol that removes at least 15 minutes from warming time yields similar rates of implantation, clinical pregnancy, spontaneous abortion, and live birth as well as similar birth weight.
Oncology
Harnessing Cancer Metabolomics to Transform Therapeutic Discovery
Researchers at Massachusetts General Hospital won a Breakthrough Award to elucidate the central roles of cancer metabolism in tumor survival and metastasis.
Orthopaedics
Chondrolabral Junction Breakdown Predicts Progression to THA After Hip Arthroscopy for Labral Tears
Michael C. Dean, BA, Scott D. Martin, MD, and colleagues are the first to identify chondrolabral junction breakdown, observed intraoperatively, as a risk factor for eventual conversion to total hip arthroplasty after hip arthroscopy for symptomatic labral tears secondary to femoroacetabular impingement.
May 31, 2024 - June 4, 2024
Conference: ASCO 2024 Annual Meeting
Leaders from the Mass General Cancer Center will present groundbreaking cancer research at this year’s ASCO 2024 Annual Meeting, held May 31 – June 4, 2024, both in-person in Chicago, IL, and virtually.
May 16-19, 2024
Conference: Heart Rhythm 2024
Massachusetts General Hospital faculty will join the global electrophysiology community at Heart Rhythm 2024, an annual meeting and educational program hosted by the Heart Rhythm Society on May 16 - 19, 2024 in Boston, MA.