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Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.

Featured In Neuroscience

A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives.

Featured In Oncology

Researchers at Massachusetts General Hospital won a Breakthrough Award to enhance personalized approaches to immunotherapy for metastatic melanoma.

Featured In Endocrinology

Melissa S. Putman, MD, and colleagues correlated findings on continuous glucose monitoring with a decline in body weight and a decline in body mass index over one year in adults with cystic fibrosis. Their data also suggest advanced glycation end products may represent a useful marker in this population.

Featured In Digestive Health

Ashwin Ananthakrishnan, MD, discusses the AGA guideline's key recommendations for managing Crohn's disease and the evolving role of biomarkers in these treatments.

Featured In Otolaryngology

Albert Edge, PhD, and colleagues have developed murine cochlear organoids that show how sensory epithelial progenitor cells differentiate into hair cells, a potential step toward developing regenerative therapies for human hearing loss.

The Latest Cardiovascular Advances

Hanna Barnes, MD, Christian Lino Cardenas, PhD, PharmD, Rajeev Malhotra, MD, and colleagues add to the understanding of the genetic basis of coronary artery calcification by identifying 43 candidate genes at 11 chromosomal locations and demonstrating effects on cellular reprogramming leading to vascular calcification.

Moussa Mansour, MD, and colleagues showed in the ADVENT registrational trial of the Farapulse system that among patients with atrial fibrillation, pulsed-field ablation was noninferior to conventional thermal ablation with respect to efficacy and device- and procedure-related serious adverse events within one year.

Contributing Physicians

Interventional Cardiologist and Physician-scientist, Massachusetts General Hospital , Instructor in Medicine, Harvard Medical School

Director, Cardiovascular Disease Fellowship, Co-Director, Mass General Cardiovascular Disease and Pregnancy Service, Massachusetts General Hospital, Associate Professor of Medicine, Harvard Medical School

Doreen DeFaria Yeh, MD

Advances Specialties

OB/GYN

Victoria S. Jiang, MD, Charles L. Bormann, PhD, and colleagues found that compared with standard blastocyst warming, a simpler protocol that removes at least 15 minutes from warming time yields similar rates of implantation, clinical pregnancy, spontaneous abortion, and live birth as well as similar birth weight.

Oncology

Scientists are working towards new, innovative approaches to faster and more accurate diagnoses, less invasive treatments, predictive medicine, and more. With new leadership and collaborations, the Toth Center at Mass Eye and Ear is making great headway for the future of head and neck cancer care.

Orthopaedics

Martin Magnéli, MD, PhD, Kartik Varadarajan, PhD, and colleagues have developed two convolutional neural networks that can read plain radiographs and classify hips as dysplastic or non-dysplastic with 83% to 92% accuracy, and detect the severity of hip dysplasia based on the Crowe or Hartofilakidis classifications.

Education & Training Opportunities

May 31, 2024 - June 4, 2024

Leaders from the Mass General Cancer Center will present groundbreaking cancer research at this year’s ASCO 2024 Annual Meeting, held May 31 – June 4, 2024, both in-person in Chicago, IL, and virtually.

May 16-19, 2024

Massachusetts General Hospital faculty will join the global electrophysiology community at Heart Rhythm 2024, an annual meeting and educational program hosted by the Heart Rhythm Society on May 16 - 19, 2024 in Boston, MA.