Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Pulmonary and Critical Care
Glycocalyx Studies Bring Precision Medicine to Critical Care
Massachusetts General Hospital physician-scientists are investigating ways to personalize medicine in the ICU, including research around alveolar epithelial glycocalyx function.
Featured In Otolaryngology
Changing Lives With a Device for the Tongue
A new study from Mass Eye and Ear has proven the safety and efficacy of using hypoglossal nerve stimulation to treat obstructive sleep apnea in children with Down syndrome—and has uncovered exciting new clues on the treatment's impact on neurocognition.
Featured In Cardiovascular
Driving Pig Organ Xenotransplantation Towards Clinical Trials
Massachusetts General Hospital research is driving improved results in preclinical xenotransplantation models, paving the way for future human clinical trials.
Featured In Orthopaedics
Revision ACL Reconstruction With Concomitant Femoral Tunnel Bone-Dowel Allograft Grafting
Courtesy of AAOS Orthopaedic Video Theater, Mass General Brigham Sports Medicine surgeon Peter Asnis, MD, performs a femoral tunnel bone-dowel allograft grafting during a revision ACL reconstruction.
Featured In Neuroscience
Diminished Frontal Pole Size, Functional Connectivity Linked to Elevated Suicide Risk in Young Adults
Gwang-Won Kim, PhD, Maurizio Fava, MD, Daphne J. Holt, MD, PhD, and colleagues published evidence that reduced frontal pole size and reduced functional connectivity between the frontal pole and the inferior frontal cortex are markers of elevated suicidality in young adults.
The Latest OB/GYN Advances
De Novo Stress Urinary Incontinence Common After Laparoscopic Sacrocolpopexy
Youngwu Kim, MD, Emily Von Bargen, DO, and colleagues found that of 169 stress-continent women who underwent minimally invasive sacrocolpopexy, 30 (18%) developed stress urinary incontinence (SUI). An existing calculator for determining the risk of postoperative de novo SUI performed moderately well in the cohort.
Lymph Node Evaluation Underutilized for Early-stage Vulvar Cancer
Massachusetts General Hospital researchers found in a nationwide study that contrary to guidelines, 34% of eligible patients with early-stage vulvar cancer did not undergo lymph node evaluation. Among patients 80 and older, the figure was 49%, even though withholding lymph node assessment did not improve survival.
Contributing Physicians
Annekathryn Goodman, MD
Director, Gynecology Oncology, Gynecologic Oncology Clerkship, Co-director, MGH Women's Global Health
Marcela G. del Carmen, MD
Chief Medical Officer, Massachusetts General Physicians Organization and Massachusetts General Hospital, Gynecologic Oncologist, Department of Obstetrics and Gynecology, Clinician, Center for Gynecologic Oncology, Mass General Cancer Center
Advances Specialties
Geriatrics and Palliative Care
Social Worker–led Serious Illness Conversations Feasible in the ED
Emily L. Aaronson, MD, MPH, Jeffrey L. Greenwald, MD, and colleagues conducted a randomized pilot trial in which emergency department social workers had serious illness conversations with 66% of older adults with potential palliative care needs—on top of their usual duties—and 77% of patients appreciated the talk.
Pulmonary and Critical Care
TPVR Offers Lower-risk Option for Pulmonary Regurgitation
Massachusetts General Hospital performs advanced transcatheter pulmonary valve replacement (TPVR) to immediately relieve pulmonary regurgitation without open-heart surgery.
Urology
Primary Prostate Cancer Establishes a Suppressive Immune Microenvironment
Through careful unraveling of the cellular and molecular landscape of prostate cancer, Massachusetts General Hospital researchers observed a highly immune-suppressive tumor microenvironment with a pattern of angiogenic gene expression, findings that will help identify targets amenable to therapeutic interventions.
May 12, 2023
Conference: Midlife Women's Health 2023: A Multidisciplinary Approach to Care
The Midlife Women's Health 2023 course is led by a multidisciplinary group of experts from Massachusetts General Hospital who will present on midlife mood disorders, cancer survivorship, skin health, recurrent UTIs, obesity, cardiovascular health, transgender medicine, early menopause, menopausal hormone therapy, and novel non-hormonal options for hot flashes.
March 22-25, 2023
Conference: SSO 2023 International Conference on Surgical Cancer Care
On March 22 - 25, 2023, the Society of Surgical Oncology hosts its International Conference on Surgical Cancer Care in Boston, MA. Colleagues from the Mass General Cancer Center will present their latest research at the conference.
Brain mechanisms of vagus nerve stimulation and stress reduction training for migraine
The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.
PILOT STUDY EVALUATING THE IMPACT OF STRESS REDUCTION ON ATHEROSCLEROTIC INFLAMMATION
We are seeking individuals who self-identify as having high stress to participate in a randomized study using a mindfulness-based, stress-reduction intervention and PET-MR imaging.
