Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In OB/GYN
Ensuring OB/GYN Care is Gender-affirming Care
Massachusetts General Hospital physicians collaborate across disciplines to ensure that OB/GYN care for transgender patients is safe, inclusive, and affirming.
Featured In Digestive Health
An Epigenetic Approach to Treating Pancreatic Cancer
The Liss Laboratory at Massachusetts General Hospital is applying an epigenetic approach to reveal the regulatory pathways used by pancreatic cancer to evade early detection and treatment.
Featured In Cardiovascular
Medical Grand Rounds: Sports Cardiology, Pregnancy and Future Cardiovascular Health
In a Cardiology Medical Grand Rounds presentation, Michael Honigberg, MD, MPP, and James Sawalla Guseh, MD, of the Corrigan Minehan Heart Center at Massachusetts General Hospital, presented on the implications of pregnancy history for preventive cardiovascular care and the emerging discipline of sports cardiology.
Featured In Orthopaedics
The Harvard Combined Orthopaedic Residency Program: A Continued Commitment to Excellence
Christopher Bono, MD, assumes the program directorship of the Harvard Combined Orthopaedic Residency Program with a shared responsibility for training the next generation of orthopedic surgeons.
Featured In Neuroscience
ALS Therapy Research and Development: Insights from Merit Cudkowicz, MD, MSc
Clinical trials of amyotrophic lateral sclerosis (ALS) therapeutic strategies coordinated through Massachusetts General Hospital are prolonging patient life.
The Latest Pulmonary and Critical Care Advances
Research Reveals Novel Molecular Mechanisms Specific to Allergic Asthma
Researchers at Massachusetts General Hospital combine advanced techniques to identify novel pathways and cell interactions associated with allergic asthma.
Smoking History Predicts Efficacy of Immune Checkpoint Inhibitors in Metastatic Non–Small-Cell Lung Cancer
David C. Christiani, MD, MPH, and colleagues suggest smoking history as an independent surrogate for tumor mutation burden when deciding which patients with advanced non–small-cell lung cancer would benefit from immune checkpoint inhibitor therapy, as smoking pack-years complemented PD-L1 tumor proportion score.
Contributing Physicians
David Christopher Christiani, MD, MPH
Director of the Christiani Lab, Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Staff Physician, Pulmonary and Critical Care Unit, Professor of Medicine, Harvard Medical School
Jehan W. Alladina, MD
Physician, Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Instructor in Medicine, Harvard Medical School
Advances Specialties
Geriatrics and Palliative Care
Special Report: Dedicated Palliative Care Team for Spanish-Speaking ICU Patients During COVID-19
During the first peak of COVID-19, Carine Davila, MD, MPH, Mark Stoltenberg, MD, MPH, MA, and colleagues operated a dedicated palliative care team for Spanish-speaking ICU patients. Over its two months of operation, 22 patients were enrolled and had an average of eight visits, and 68% changed their code status.
Neuroscience
Genetic Patterning for Psychopathology Is Distinct in Children and Adults
Dylan E. Hughes, Joshua L. Roffman, MD, MMSc and colleagues found that psychopathology in children is most strongly related to a neurodevelopmental polygenic score comprising overlapping variants across ADHD, autism spectrum disorder, MDD and Tourette's, rather than to disease-specific polygenic scores as in adults.
Urology
Auto-Contouring Model Performs Well for Prostate Cancer Patients Who Receive Radiopaque Hydrogel Spacer
Yi Wang, PhD, Jason A. Efstathiou, MD, DPhil, and colleagues have validated a CT-based deep learning model that provides automated contouring when planning radiation therapy for prostate cancer patients who receive the SpaceOAR Vue rectal spacer.
June 2-6, 2023
Conference: ASCO 2023 Annual Meeting
Leaders from the Mass General Cancer Center will present groundbreaking cancer research at this year’s ASCO 2023 Annual Meeting, held June 2–6, 2023, both in-person in Chicago, IL, and virtually.
June 15-18, 2023
Conference: The Endocrine Society 2023 Annual Meeting
Leaders from the Endocrinology Division at Massachusetts General Hospital are honored to join international colleagues at this year’s Endocrine Society Annual Meeting in Chicago, IL on June 15–18, 2023.
Brain mechanisms of vagus nerve stimulation and stress reduction training for migraine
The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.
PILOT STUDY EVALUATING THE IMPACT OF STRESS REDUCTION ON ATHEROSCLEROTIC INFLAMMATION
We are seeking individuals who self-identify as having high stress to participate in a randomized study using a mindfulness-based, stress-reduction intervention and PET-MR imaging.
