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Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.

Featured In Cardiovascular

A recent Massachusetts General Hospital study suggests that exercise nearly doubles cardiovascular benefits in individuals with anxiety or depression. Their findings support previous evidence that regular physical activity benefits heart health by activating parts of the brain that counteract stress.

Featured In Neuroscience

Massachusetts General Hospital's Clinical and Translational Research Unit (CTRU) supports investigators conducting complex brain disorders research.

Featured In Oncology

Marc D. Succi, MD, Ottavia Zattra, and colleagues warn oncologists to plan for a surge of new and more advanced cancer diagnoses in upcoming months and years because of suboptimal CT imaging during—and after—the peak of the COVID-19 pandemic.

Featured In Digestive Health

Raymond T. Chung, MD, vice chief of the Division of Gastroenterology and director of Hepatology and the Liver Center, and colleagues defined a molecular signature that predicts progression of early-stage liver fibrosis within five years in an etiology-agnostic manner, which can inform anti-fibrotic drug development.

Featured In Pulmonary and Critical Care

Severe COVID-19 may shift from being primarily lung-localized to a systemic disease, Massachusetts General Hospital researchers say. They noted early peaks in alveolar markers but later peaks in endothelial markers associated with renin–angiotensin system dysfunction, cardiac and kidney injury, and 28-day outcome.

The Latest Neuroscience Advances

Researchers in the Department of Psychiatry have identified unique emotional concerns about exercise among patients who have undergone metabolic/bariatric surgery, which may prevent them from adopting the high level of physical activity that's recommended to maintain weight loss and prevent cardiovascular disease.

In a real-world analysis of patients treated with endovascular thrombectomy for stroke due to emergent large vessel occlusion, Massachusetts General Hospital researchers found women and men had comparable reperfusion rates and 90-day functional outcomes, even though women were older and had more pre-stroke disability.

Contributing Physicians

Associate Chief for Research, Department of Psychiatry, Massachusetts General Hospital, Director, Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health

Chief of Stroke Division, Department of Neurology, Massachusetts General Hospital, Professor of Neurology, Harvard Medical School

Advances Specialties


The risk of late-onset atrial fibrillation after surgical aortic valve replacement is only 4%, according to a study by Thoralf M. Sundt, MD, Chin Siang Ong, MBBS, PhD, and colleagues. Prophylactic tissue ablation or ligation/amputation of the left atrial appendage may not be warranted at the time of surgery.

Digestive Health

Kumar Krishnan, MD, of Massachusetts General Hospital, and Charu Paranjape, MD, MBBS, of Newton-Wellesley Hospital, have created a new course called the Minimally Invasive and Novel Therapeutics (MINT), which focuses on the coordinated care of patients with foregut disease.


Aditya V. Karhade, MD, MBA, Joseph H. Schwab, MD, MS, and colleagues found free-text discharge summary notes have the greatest utility in a natural language processing algorithm for predicting the risk of readmission after posterior lumbar fusion. Progress notes had the least utility.

Education & Training Opportunities

May 13, 2022

Midlife Women’s Health 2022 provides a multi-disciplinary approach to the care of menopausal women. In this course, a multidisciplinary group of experts from Massachusetts General Hospital will present on migraine, perimenopause, type 2 diabetes, Alzheimer’s disease, bariatric surgery, emotional intelligence, hyperlipidemia, mindfulness, menopausal hormone therapy and more.

May 13, 2022

This CME course, offered by the The Corrigan Minehan Heart Center at Massachusetts General Hospital, is designed to educate clinicians about current cardiac intensive care topics and give them the medical knowledge necessary to provide comprehensive, guideline-based and best-practice in care to modern cardiac intensive care patients.

Clinical Trials

In Neuroscience

The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.

In Cardiovascular

We are seeking individuals who self-identify as having high stress to participate in a randomized study using a mindfulness-based, stress-reduction intervention and PET-MR imaging.