Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Neuroscience
The Future of Neurosurgery and Neuroscience at Mass General: Q&A With Bob S. Carter, MD, PhD
Bob S. Carter, MD, PhD, is the chief of the Department of Neurosurgery at Massachusetts General Hospital. In this Q&A, Dr. Carter elaborates on intraoperative molecular diagnostics. Dr. Carter is also a 2021 Congress of Neurological Surgeons (CNS) honored guest.
Featured In Digestive Health
Improving Patient Outcomes with J-Pouch Surgery
Richard A. Hodin, MD, discusses his surgical work, the improved outcomes he sees in patients who undergo J-pouch surgery and his experience maintaining longer-term relationships with patients.
Featured In Orthopaedics
Kinematic Sequence More Important Than Pitch Delivery Approach for Preventing Baseball Injuries
Researchers in the Sports Medicine Service have determined that instructing baseball pitchers in the ideal kinematic sequence (the pattern of energy transfer in the body) could protect them from injury to the shoulder and elbow, regardless of whether they throw from the traditional windup or the stretch delivery.
Featured In Urology
Advancing Trimodality Therapy for Bladder Cancer
Researchers explore long-term outcomes and options for bladder cancer recurrence after combination treatment using transurethral resection and chemoradiation.
Featured In Endocrinology
Novel Strategy Identified for Treating Osteoporosis
Cheng-Chia Tang, PhD, and Marc N. Wein, MD, PhD, of the Endocrine Unit, and colleagues demonstrated in a preclinical osteoporosis model that an oral drug, YKL-05–099, boosts bone formation and trabecular bone mass—and unlike current anabolic osteoporosis therapies, inhibits bone resorption.
The Latest Cardiovascular Advances
Pre-Epicardial Cells Generated from Stem Cells Expected to Improve Engineered Heart Tissue
Harald C. Ott, MD, and Jun Jie Tan, DPhil, of the Center for Regenerative Medicine, and colleagues have devised a straightforward method of generating pre-epicardial cells that should play a key role in creating bioengineered heart tissue to treat patients with heart failure.
ADAMTS7 Knockdown Might Treat Atherosclerosis
Patrick T. Ellinor, MD, PhD, of the Demoulas Center for Cardiac Arrhythmias at Massachusetts General Hospital, Sekar Kathiresan, MD, formerly of the Center for Genomic Medicine, and colleagues have demonstrated that the catalytic domain of ADAMTS7 is a promising therapeutic target for coronary artery disease.
Contributing Physicians
Judy Wei-Ming Hung, MD
Director of the Echocardiography Lab, Division of Cardiology, Professor of Medicine, Harvard Medical School
Patrick T. Ellinor, MD, PhD
Director, Cardiac Arrhythmia Service
Advances Specialties
Geriatrics and Palliative Care
Older Age Alone Should Not Rule Out Intensive Treatment of Aggressive Non-Hodgkin's Lymphoma
Massachusetts General Hospital researchers demonstrated that intensive therapy for aggressive non-Hodgkin's lymphoma has survival benefits across all age brackets of older adults, and they identified factors associated with greater risk of toxicities and unplanned hospitalization.
OB/GYN
Maternal and Placental Immune Responses to SARS-CoV-2 Differ by Fetal Sex
Massachusetts General Hospital researchers present evidence that fetal sex plays a key role in modifying maternal humoral responses and placental innate and adaptive immune responses. They found significantly reduced transfer of SARS-CoV-2–specific antibodies to male fetuses.
Pulmonary and Critical Care
High-dose Inhaled Nitric Oxide Safe, Effective for Non-Intubated COVID-19 Patients
Lorenzo Berra, MD, and Bijan Safaee Fakhr, MD, of the Department of Anesthesia, Critical Care and Pain Medicine, and colleagues found that high-dose inhaled nitric oxide produced a beneficial effect on the respiratory system of non-intubated hospitalized COVID-19 patients without adverse events.
December 8, 2021 - July 13, 2022
Grand Rounds: Mass General Cardiology Grand Rounds
The Massachusetts General Hospital Corrigan Minehan Heart Center prepares future health care professionals and trains providers in innovative therapies and care. As part of these efforts, the center hosts regular Grand Rounds presentations from thought leaders and researchers on important cardiology topics. Cardiology Grand Rounds is open to all healthcare professionals.
November 5-6, 2021
CME: Short Term Mechanical Support Heart and Lung Symposium
The Mass General Short-term Heart/Lung Support Symposium is designed to provide the opportunity to learn, ask questions, participate in simulation exercises and review the rare but potentially fatal problems that can occur with all forms of mechanical assist in a low stress environment for all team members.
Brain mechanisms of vagus nerve stimulation and stress reduction training for migraine
The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Assess the Efficacy and Safety of JNJ-63733657, an Anti-tau Monoclonal Antibody, in Participants with Early Alzheimer's Disease
We are looking for adults 55-80 years old with Alzheimer's Disease to receive infusions of an experimental drug, JNJ-63733657, or a placebo (inactive) infusion. This study will help us determine the safety and efficacy of JNJ-63733657.
