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Featured
Advances in Epilepsy Surgery
In this video, Ziv WIlliams, MD, describes new advances in epilepsy surgery such as responsive neural stimulators, which identify seizure activity, stimulate the areas causing seizures and stop them, and thermal laser ablation, which uses pulses of laser light to remove areas that are causing seizures.
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Featured
Loading Dose of Antiepileptic Reduces Seizure Risk During Functional Mapping
The risk of triggering intraoperative seizures during functional mapping of the cortex was cut nearly in half by administering a loading dose of an antiepileptic drug just before surgery.
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Featured
Why Mass General Neurologists Are Animated About Big Data
Neurologists at Massachusetts General Hospital are using big data and machine learning to make better and more informed decisions on patient care.
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Guidance for Treatment of Epileptiform Activity in Critically Ill Patients
Massachusetts General Hospital researchers provide evidence that interventions for epileptiform activity in critically ill patients should prioritize those with average epileptiform activity burden ≥10%, be more conservative when maximum epileptiform activity is low, and be tailored to the preadmission profile.
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Intracranial Stereo-EEG Resolves Discordant Clinical vs. Neuroimaging Findings in Patient With Tonic–Clonic Seizures
Irfan S. Sheikh, MD, Mark Richardson, MD, PhD, Sydney S. Cash, MD, PhD, and colleagues present an instructive case in which intracranial stereo-EEG resolved discordance between clinical, MRI, and scalp EEG findings, allowing diagnosis of focal cortical dysplasia type 2b and resection that led to seizure freedom.
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Barques Are Generated in Posterior Human Hippocampus
Vasileios Kokkinos, PhD, Mark Richardson, MD, PhD, and colleagues have determined that barques—variant findings on intracranial EEG—are highly specific to the posterior human hippocampus, an important observation for differentiating barques from interictal epileptic activity.
Epilepsy Contributors
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
Co-transplantation of Regulatory T Cells Improves Cell Replacement Therapy for Parkinson's Disease -
Eric S. Rosenthal, MD
Associate Director of the Neurosciences Intensive Care Unit, Director, Neurocritical Care Fellowship Training Program, Director, Critical Care Neuromonitoring
Recent Article
Minimally Invasive Electrocorticography, Continuous EEG Do Not Reliably Detect Spreading Depolarizations -
Erica Seiguer Shenoy, MD, PhD
Associate Physician, Massachusetts General Hospital, Associate Chief of the Infection Control Unit, Massachusetts General Hospital
Recent Article
Diagnostic Algorithm Supports Evaluation of Hospitalized COVID-19 Patients After Initial Negative Test -
Jeffrey S. Schweitzer, MD, PhD
Neurosurgeon, Department of Neurosurgery, Massachusetts General Hospital, Assistant Professor of Neurosurgery, Harvard Medical School
Recent Article
Essential Tremor Treatment Advancements Using MRI-guided Focused Ultrasound: Q&A With Jeffrey S. Schweitzer, MD, PhD -
M. Brandon Westover, MD, PhD
Physician Investigator (Cl), Neurology, Mass General Research Institute, Associate Professor of Neurology, Harvard Medical School, Associate Neurologist, Neurology, Massachusetts General Hospital
Recent Article
Guidance for Treatment of Epileptiform Activity in Critically Ill Patients -
Mirela Simon, MD
Medical Director, Intraoperative Neurophysiology Unit, Neurology Service, Massachusetts General Hospital
Recent Article
Direct Cortical Recordings Feasible for Monitoring Thalamocortical Tract During Craniotomy -
Robert (Mark) Richardson, MD, PhD
Director of Functional Neurosurgery, Massachusetts General Hospital
Recent Article
Intracranial Stereo-EEG Resolves Discordant Clinical vs. Neuroimaging Findings in Patient With Tonic–Clonic Seizures -
Sydney S. Cash, MD, PhD
Co-Director, Center for Neurotechnology and Neurorecovery, Associate, Department of Neurology, Massachusetts General Hospital, Professor of Neurology, Harvard Medical School
Recent Article
Single-Neuron Recordings Show How the Brain Plans Speech -
W. Taylor Kimberly, MD, PhD
Associate Director, Neuroscience Intensive Care Unit, Chief, Division of Neurocritical Care and Emergency Neurology
Recent Article
Plasma Hypoxanthine Is a Biomarker of Brain Edema After Ischemic Stroke -
Ziv Williams, MD
Neurosurgeon, Department of Neurosurgery, Massachusetts General Hospital, Associate Professor in Neurosurgery, Harvard Medical School
Recent Article
Single-Neuron Recordings Show How the Brain Plans Speech