Posts by Mirela Simon, MD
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Direct Cortical Recordings Feasible for Monitoring Thalamocortical Tract During Craniotomy
Monitoring thalamocortical afferents via direct cortical recordings is feasible during brain tumor surgery, Massachusetts General Hospital researchers have demonstrated. Sometimes, changes in surgical management in response to somatosensory changes evoked potentials prevented worsening of preoperative sensory deficits.
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Case Reports: Mapping of the Thalamocortical Tract in Asleep Craniotomies
Mirela V. Simon, MD, MSc, of the Department of Neurology, William T. Curry, MD, of the Department of Neurosurgery, and colleagues have conducted the first successful electrophysiologic mapping of the thalamocortical tract during supratentorial surgery under general anesthesia in humans.
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Dynamic Mapping of the Corticospinal Tract for Surgeries Beyond Tumor Resection
Physicians at Massachusetts General Hospital are the first to report continuous corticospinal tract mapping during high-risk procedures other than resection of intramedullary tumors.
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Loading Dose of Antiepileptic Reduces Seizure Risk During Functional Mapping
The risk of triggering intraoperative seizures during functional mapping of the cortex was cut nearly in half by administering a loading dose of an antiepileptic drug just before surgery.
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The Survival Advantage: How the Intraoperative Neurophysiology Monitoring Unit at Mass General Lowers Surgical Risk and Improves Prognosis
The Intraoperative Neurophysiologic Monitoring and Mapping (IONM) unit at Massachusetts General Hospital has been a driving force behind increased surgical success with reduced neurological complications.
Biography
Dr. Simon received her Medical degree from Carol Davila University of Medicine and Pharmacy, Bucharest, Romania and a Master of Science degree in Epidemiology from Harvard School of Public Health. She did her Neurology residency training at Boston University Medical Center followed by a two-year clinical neurophysiology/epilepsy Fellowship at Massachusetts General Hospital. Dr. Simon joined the faculty at Mass General in 2003 and since then has served in the Department of Neurology. She is currently an Associate Professor of Neurology at Harvard Medical School.
Dr. Simon's main research interests include improving and development of new methods of neurophysiologic mapping of the central nervous system (CNS) as well as the neurophysiology of increased cortical excitability and CNS ischemia. She has a broad clinical interest in clinical neurophysiology, particularly its intraoperative applications for prevention of postoperative neurologic deficits and for epilepsy surgery.