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Featured
Review: Pathways of Colorectal Carcinogenesis
Dozens of different somatic mutations have been identified in colorectal tumors, but colorectal cancer appears to develop via one of only a few distinct pathways.
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Featured
Review: Lifestyle Factors, Changes in Gut Microbiota Are Linked in Development of Colorectal Cancer
Both diet, lifestyle and the gut microbiome have been implicated in colorectal tumorigenesis. Accumulating evidence suggests these two influences are related and may point the way to better prevention strategies.
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Featured
Fiber Intake Has Survival Benefit in Patients Already Diagnosed with Colorectal Cancer
In the first prospective study of the topic, gastroenterologists and epidemiologists at Massachusetts General Hospital found that higher fiber intake after a diagnosis of nonmetastatic colorectal cancer is associated with longer survival.
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Guidelines: Diagnosis and Management of Gastrointestinal Subepithelial Lesions
Brian Jacobson, MD, MPH, served as first author of the American College of Gastroenterology's clinical practice guidelines about diagnosis and management of subepithelial lesions, which include 11 recommendations, a list of six key concepts, and an evidence-based algorithm.
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Mortality Risk Significantly Greater With Interval CRC Than Screen-detected CRC
Keming Yang, MD, PhD, Andrew T. Chan, MD, MPH, and colleagues detected significantly increased mortality for individuals with interval colorectal cancer (CRC) than for those with screen-detected CRC, and differences in established clinical prognostic factors, genetic characteristics, could not explain the discrepancy.
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Initiating Screening Before Age 50 Reduces Risk of Colorectal Cancer
Researchers at Massachusetts General Hospital found that starting endoscopic screening before age 50 is associated with a greater reduction in the absolute risk of colorectal cancer compared with starting at later ages. The data support national recommendations to start screening at age 45 for average-risk individuals.
Mass General Cancer Center Contributors
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Daniel C. Chung, MD
Medical Co-Director, Center for Cancer Risk Assessment, Director, High-Risk GI Cancer Clinic, Mass General Cancer Center, Professor of Medicine, Harvard Medical School
Recent Article
Pilot Study: Virtual Reality Is a Feasible Alternative to Narcotics During Colonoscopy
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David L. Berger, MD
Colorectal and Gastrointestinal Surgeon, Massachusetts General Hospital Division of General Surgery, Associate Professor of Surgery, Harvard Medical School
Recent Article
Primary Tumor Resection Improves Survival in Advanced Colorectal Cancer
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Hiroko Kunitake, MD, MPH
Gastrointestinal and Colorectal Surgeon, Surgical Director, Perioperative Optimization of Senior Health (POSH) Clinic, Massachusetts General Hospital, Assistant Professor of Surgery, Harvard Medical School
Recent Article
New Multidisciplinary Clinic Aims to Improve Surgical Outcomes in Older Adults -
Liliana G. Bordeianou, MD, MPH, FACS, FASCRS
Site Director of the Colorectal Surgery Program, Co-Director, Pelvic Floor Disorders Center, Mass General, Co-Chair, Mass General Brigham Colorectal Surgery Collaborative, Professor of Surgery, Harvard Medical School
Recent Article
New Scoring System Allows Assessment of the Severity of Ileoanal Pouch Syndrome
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
