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Featured
Review: Pathways of Colorectal Carcinogenesis
Dozens of different somatic mutations have been identified in colorectal tumors, but colorectal cancer appears to develop via one of only a few distinct pathways.
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Featured
Review: Lifestyle Factors, Changes in Gut Microbiota Are Linked in Development of Colorectal Cancer
Both diet, lifestyle and the gut microbiome have been implicated in colorectal tumorigenesis. Accumulating evidence suggests these two influences are related and may point the way to better prevention strategies.
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Featured
Fiber Intake Has Survival Benefit in Patients Already Diagnosed with Colorectal Cancer
In the first prospective study of the topic, gastroenterologists and epidemiologists at Massachusetts General Hospital found that higher fiber intake after a diagnosis of nonmetastatic colorectal cancer is associated with longer survival.
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Anatomic Classification of Colorectal Cancer Is Too Broad for Accurate Risk Prediction
Risk factor profiles for colorectal cancer differ when the proximal colon, distal colon and rectum are reclassified as seven distinct sites.
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Sulfur-metabolizing Bacteria Linked to Increased Risk of Colorectal Cancer
Long-term adherence to a dietary pattern associated with sulfur-metabolizing bacteria in stool is associated with increased risk of distal colon and rectal cancer, according to data from the Health Professionals Follow-up Study.
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Primary Tumor Resection Improves Survival in Advanced Colorectal Cancer
A prospective registry study confirms improved survival after primary tumor resection in patients with stage IV colorectal cancer, but surgery was associated with a high morbidity rate.
Colorectal Cancer contributors
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Daniel C. Chung, MD
Clinical Chief, Gastrointestinal Unit, Director, High-Risk GI Cancer Clinic
Recent Article
Review: Pathways of Colorectal Carcinogenesis -
David L. Berger, MD
Colorectal and Gastrointestinal Surgeon, Massachusetts General Hospital Division of General Surgery, Associate Professor of Surgery, Harvard Medical School
Recent Article
Primary Tumor Resection Improves Survival in Advanced Colorectal Cancer -
Hiroko Kunitake, MD
Colorectal Surgeon, Center for Pelvic Floor Disorders, Massachusetts General Hospital, Assistant Professor of Surgery, Harvard Medical School
Recent Article
New Research Further Quantifies Benefits of Preventative Colonoscopy Screening -
Liliana G. Bordeianou, MD, MPH, FACS, FASCRS
Chief, Colorectal Surgery Program, Massachusetts General Hospital, Co-Director, Pelvic Floor Disorders Center, Associate Professor of Surgery, Harvard Medical School
Recent Article
Surgeons Should Evaluate More Than Fecal Incontinence, Frequency After J-Pouch Creation