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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Featured
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
Neurologists at Mass General explore the case of a woman who endured gait disturbance, cognitive impairment and urinary incontinence for 2 years before she was diagnosed with normal-pressure hydrocephalus and successfully treated with surgical shunting.
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Featured
fMRI and EEG May Find Signals of Consciousness Earlier in Severe Traumatic Brain Injury Patients
The rate of misclassification of unconsciousness can be as high as 40%. A Mass General team studied using fMRI and EEG to better identify patients with unconsciousness in the ICU.
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Q&A With Dr. Caterina Mainero, Director of the Multiple Sclerosis Imaging Laboratory
Caterina Mainero, MD, PhD, director of the Multiple Sclerosis Imaging Laboratory in the Martinos Center for Biomedical Imaging, discusses the lab's research into the mechanisms of the disease and new approaches to diagnosis and monitoring.
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Optimal Deep Brain Stimulation Sites and Networks for Stimulation of the Fornix in Alzheimer's Disease
Andreas Horn, PhD, MD, and colleagues have reported a potentially optimal stimulation target for deep brain stimulation to the fornix for patients with Alzheimer's disease. Their findings will allow refinement of clinical trials to answer whether this treatment could be effective for more patients.
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Targeting Lipid Synthesis Efficacious in Glioblastoma Mouse Models
Katharina M. Eyme, Alessandro Sammarco, PhD, Christian E. Badr, PhD, and colleagues found YTX-7739, an orally available stearoyl coenzyme A desaturase 1 inhibitor, triggered lipotoxicity in glioblastoma stem-like cells, and with or without temozolomide, it was efficacious in mouse models of glioblastoma.
Neurology Contributors
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Brian L. Edlow, MD
Associate Director, Center for Neurotechnology and Neurorecovery (CNTR), Director, Laboratory for NeuroImaging of Coma and Consciousness (NICC), Director, Critical Care Research Neuroimaging
Recent Article
Ethical Implications of Neuroimaging That Detects Covert Consciousness
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Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Cannabis Use Disorder Can Develop Soon After a Medical Marijuana Card Is Obtained
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Nagagopal Venna, MD
Director, Neurology Clinic, Director, Neuro-Infectious Diseases Clinic, Director, Academic General Neurology Fellowship Program
Recent Article
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
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Yakeel T. Quiroz-Gaviria, PhD
Associate Professor, Harvard Medical School, Director, Familial Dementia Neuroimaging Lab, Director, Multicultural Alzheimer's Prevention Program, Massachusetts General Hospital, Paul B. and Sandra M. Edgerley MGH Research Scholar 2020-2025
Recent Article
MRI Feature Is Marker of Disease Progression in Preclinical Autosomal Dominant Alzheimer's Disease
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.