Posts by Casey A. Maguire, PhD
-
Novel AAV Capsid, Truncated ChAT Promoter Address Challenges in Intracranial Gene Therapy
Miguel C. Santoscoy, PhD, Casey A. Maguire, PhD, and colleagues have developed an adeno-associated virus capsid that transduces a broad area of the striatum upon intracranial injection in mice and a truncated human choline acetyltransferase promoter that allows efficient, selective transduction of cholinergic neurons.
Biography
Casey A. Maguire, PhD, is a gene delivery expert and associate investigator in the Mass General Research Institute at Massachusetts General Hospital and an associate professor of Neurology at Harvard Medical School.
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.