Posts by Valentina Perosa, MD
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AI Models to Assess Histopathologic Markers of Alzheimer's Disease, Cerebral Amyloid Angiopathy
Valentina Perosa, MD, and Susanne J. van Veluw, PhD, of the Department of Neurology, and colleagues have developed the first convolutional neural networks that can identify and quantify biologically relevant histopathological markers of both Alzheimer's disease and cerebral amyloid angiopathy.
Biography
Dr. Valentina Perosa’s main interest is to explore how cerebral small vessel disease contributes to cognitive impairment. After completing medical school at the University of Magdeburg, she began training as a neurologist and focused her research on ageing and neurodegenerative disease. As a postdoc, Dr. Perosa currently investigates enlarged perivascular spaces in patients with CAA, combining post-mortem MRI and histopathology. With this work, the Van Veluw Lab for Neuroimaging aims to gain more insight in the clearance mechanisms of amyloid ß in CAA, which could have repercussions in better understanding the interactions between vascular and Alzheimer’s pathology.
