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Featured
Proving Efficacy of Two Non-Drug Therapies for Hypertension
Research at the Massachusetts General Hospital Heart Center proves the effectiveness of the relaxation response and renal denervation to control high blood pressure.
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Perfusion Imaging During NO Inhalation Can Identify Patients With Pulmonary Arterial Hypertension
Researchers at Massachusetts General Hospital found that differences in pulmonary perfusion images acquired at baseline versus those acquired during vasodilation can distinguish between healthy controls and patients with pulmonary arterial hypertension, even those who had not responded to acute vasodilation.
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BP Polygenic Risk Scores May Complement Measured BP for CVD Prevention
In a prospective cohort of 331,078 middle-aged adults, So Mi Jemma Cho, PhD, Pradeep Natarajan, MD, MMSc, and colleagues observed that genetic predisposition to hypertension informed the risk of incident cardiovascular disease, independent of measured blood pressure and antihypertensive treatment.
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Acetylcholine Derived From B Cells May Protect Against Cardiovascular Disease
B cells in the bone marrow are an important source of acetylcholine, Massachusetts General Hospital researchers have discovered. B cell–derived acetylcholine regulated normal hematopoiesis and limited emergency hematopoiesis in cardiovascular disease by modulating signals produced by the bone marrow stromal niche.
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Review: Cardiometabolic–Renal Comorbidities in Gout
Hyon K. Choi, MD, Chio Yokose, MD, MS, and Natalie McCormick, PhD, of the Division of Rheumatology, Allergy and Immunology, suggest pharmacologic agents that can both lower urate levels in patients with gout and treat common cardiometabolic-renal comorbidities of the disease.
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Bone Marrow Vascular Pathologies Augment Supply of Leukocytes Implicated in CVD
Researchers from the Center for Systems Biology at Massachusetts General Hospital and colleagues address how three heart disease milestones—hypertension, atherosclerosis and myocardial infarction—impair the bone marrow's vascular health, suggesting a new direction for development of cardiovascular disease therapies.
Hypertension Contributors
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Alison S. Witkin, MD
Associate Director, Pulmonary Hypertension and Thromboendarterectomy Program, Massachusetts General Hospital
Recent Article
Studies Work to Improve Pulmonary Hypertension and HHT Care
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Gregory D. Lewis, MD
Jeffrey and Mary Ellen Jay Chair and Section Head of Heart Failure, Medical Director of Heart Transplantation
Recent Article
Ex Vivo Perfusion and Transplantation of Hearts Donated After Circulatory Death Is Safe and Effective
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Jennifer E. Ho, MD
Cardiologist, Heart Failure and Transplantation Program, Assistant Professor of Medicine, Harvard Medical School
Recent Article
Arterial Stiffness and Load Significantly Higher in Women Than Men With HFpEF
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Josanna M. Rodriguez-Lopez, MD
Director, HHT Center, Director, Pulmonary Hypertension and Thromboendarterectomy Program
Recent Article
Studies Work to Improve Pulmonary Hypertension and HHT Care
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Pradeep Natarajan, MD, MMSc
Director, Preventive Cardiology, Associate Professor of Medicine, Harvard Medical School
Recent Article
BP Polygenic Risk Scores May Complement Measured BP for CVD Prevention
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Randall Mark Zusman, MD
Director, Division of Hypertension
Recent Article
Using Renal Denervation to Treat Hypertension
Cardiovascular Care at Mass General
At Mass General, our world-class physicians and nurses specialize in specific forms of both heart and vascular disease, and work closely together to offer leading treatments and preventive care for cardiovascular conditions.