Posts by Jennifer E. Ho, MD
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Arterial Stiffness and Load Significantly Higher in Women Than Men With HFpEF
Emily Lau, MD, Jennifer E. Ho, MD, and colleagues observed arterial stiffness and load are closely tied to invasive measures of hemodynamic responses to exercise in heart failure with preserved ejection fraction. The association was particularly pronounced in women.
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Greater COVID-19 Severity in Men May Be Due to Greater Inflammatory Response
Emily S. Lau, MD, Jenna N. McNeill, MD, and Jennifer E. Ho, MD, of the Cardiovascular Research Center, and colleagues present evidence that men have more robust systemic inflammation in response to SARS-CoV-2 infection than women do, which may explain men's apparently greater risk of severe COVID-19.
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Age Influences the Effect of Risk Factors on Development of Heart Failure
Traditional risk factors have greater discriminatory value in predicting new onset of heart failure in younger adults than in older people, according to a pooled population-based cohort study by Samantha M.A. Paniagua, Sanjiv J. Shah, MD, and Jennifer E. Ho, MD, of the Cardiovascular Research Center, and colleagues.
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Clinical Diagnostic Tools May Misclassify HFpEF in Dyspnea Patients
Heart failure with preserved ejection fraction (HFpEF) can be challenging to diagnose, and recently risk scores have been developed to aid in diagnosis. For patients with chronic dyspnea, clinician-researchers in the Corrigan Minehan Heart Center sound a note of caution about using these scores including the HFA-PEFF algorithm and H2FPEF score to rule out HFpEF.
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Obesity Linked to Improved Survival of Patients with Pulmonary Hypertension
Akin to the "obesity paradox" described in heart failure, Massachusetts General Hospital researchers find that obesity in patients with pulmonary hypertension is associated with reduced mortality.
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Exercise Testing Can Unmask Abnormal Pulmonary Vascular Responses in Patients with Chronic Dyspnea
In a prospective study, exercise-induced pulmonary hypertension was associated with worse CV event–free survival even in the absence of pulmonary hypertension at rest.
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Men and Women with HFpEF Differ in Physiologic Responses to Exercise
In a study that may improve the understanding of pathophysiologic mechanisms, women and men who had heart failure with preserved ejection fraction (HFpEF) differed in cardiac and skeletal muscle responses to exercise. Women with HFpEFexhibited worse systolic reserve, diastolic reserve and peripheral oxygen extraction.
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Different Definitions of HFpEF Have an Impact on Patient Outcomes
The various definitions of heart failure with preserved ejection fraction (HFpEF) miss up to 85% of patients with abnormal rest or exercise filling pressures, cardiologists at Massachusetts General Hospital have found. Better hemodynamic phenotyping is needed to target patients at highest risk.
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Leveraging Social Media in Medicine
A group from the Massachusetts General Hospital Corrigan Minehan Heart Center discusses how they leverage social media as both practicing clinicians and active researchers.
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#AHA17 Video: Scientific Sessions in Summary
Mass General physicians presented on the podium, moderated sessions or showcased posters over 50 times at the American Heart Association 2017 Scientific Sessions. Some of them answered the question: “What was the most interesting topic presented at this year’s Scientific Sessions?"
Biography
Dr. Ho is a cardiologist in the Heart Failure and Transplantation section of the Massachusetts General Hospital Cardiology Division and Assistant Professor of Medicine at Harvard Medical School. She sees patients with advanced heart failure.
Dr. Ho is a faculty member of the Cardiovascular Research Center, and also maintains an affiliation with the Framingham Heart Study. Her laboratory is focused on clinical and translational patient-oriented investigations to understand mechanisms driving heart failure and cardiometabolic disease, with a particular focus on heart failure with preserved ejection fraction. She is a recipient of the MGH Claflin Distinguished Scholar Award (2017), an MGH Hassenfeld Scholar Award (2016), and multiple NIH grants to support her research laboratory.
Cardiovascular Care at Mass General
At Mass General, our world-class physicians and nurses specialize in specific forms of both heart and vascular disease, and work closely together to offer leading treatments and preventive care for cardiovascular conditions.