Advances in Motion provides health care professionals with information about latest breakthroughs, research and clinical advances from Massachusetts General Hospital.
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Featured In Cardiovascular
Study Shows Sedentary Time Increases Cardiovascular Disease
Sedentary time negatively impacts heart health regardless of whether a person follows exercise guidelines.
Featured In Neuroscience
From Stroke Detection to Cancer Screening: AI Tools Advancing Imaging Efficiency
Mass General Brigham has developed initiatives for artificial intelligence (AI) governance and inclusion of medical expertise to address an influx of AI technology in medical imaging.
Featured In Oncology
Optimizing Treatment Alternatives for Relapsed/Refractory T Cell Lymphomas
Massachusetts General Hospital leads the global PETAL consortium to advance the understanding and treatment of newly diagnosed and relapsed/refractory T cell lymphomas.
Featured In Rheumatology, Allergy and Immunology
Innovations in Allergy Immunotherapy: Perspectives From Sarita Patil, MD
Food allergies represent a growing public health concern, affecting millions of individuals globally and posing significant clinical and quality-of-life challenges. However, their efficacy remains inconsistent, with only a subset of patients achieving long-term tolerance.
Featured In Ophthalmology
Non-invasive OCTA Imaging Biomarker Tied to Neovascular Glaucoma in Patients With Proliferative Diabetic Retinopathy
John B. Miller, MD, Edward S. Lu, MD, and colleagues found retinal ischemia on widefield swept-source optical coherence tomography angiography was associated with 13-fold increased odds of neovascular glaucoma, a vision-threatening complication in patients with proliferative diabetic retinopathy.
The Latest Oncology Advances
Digital App Improves Quality of Life for Caregivers of Patients Undergoing HSCT
A digital app created by Jamie M. Jacobs, PhD, Areej El-Jawahri, MD, and colleagues significantly improved quality of life, depression and PTSD symptoms, and coping skills of family and friend caregivers of patients undergoing hematopoietic stem cell transplantation, compared with usual care.
Off-Label Treatment Offers Hope for Patients With Rare Medullary Thyroid Cancer
Oncologists at Massachusetts General Hospital are developing ways to use a lung cancer medication off-label for advanced, recurrent medullary thyroid cancer.
Contributing Physicians
Genevieve M. Boland, MD, PhD
Vice Chair of Research, Department of Surgery, Massachusetts General Hospital, Section Head, Melanoma and Sarcoma Surgery Programs, Surgical Director, Termeer Center for Targeted Therapies, Mass General Brigham Cancer Institute
Marcela V. Maus, MD, PhD
Director, Cellular Immunotherapy Program, Mass General Brigham Cancer Institute, Associate Professor of Medicine, Harvard Medical School
Advances Specialties
Cardiovascular
Aficamten Monotherapy Superior to Metoprolol Monotherapy for Obstructive Hypertrophic Cardiomyopathy
Michael A. Fifer, MD, and an international team found that monotherapy with aficamten, including as first-line therapy, provided greater decreases in symptoms and improvement in exercise capacity than the current standard therapy with metoprolol.
Neuroscience
Digital App Improves Quality of Life for Caregivers of Patients Undergoing HSCT
A digital app created by Jamie M. Jacobs, PhD, Areej El-Jawahri, MD, and colleagues significantly improved quality of life, depression and PTSD symptoms, and coping skills of family and friend caregivers of patients undergoing hematopoietic stem cell transplantation, compared with usual care.
Orthopaedics
Value of Hip Arthroscopy for Femoroacetabular Impingement Varies by Procedure Type, Preoperative Function
Scott D. Martin, MD, and colleagues say the value of hip arthroscopy for femoroacetabular impingement, when analyzed with time-driven activity-based costing, varies widely according to preoperative patient-reported function as well as osteoplasty type and other intraoperative factors.
May 9, 2025
Conference: Midlife Women's Health 2025: A Multidisciplinary Approach to Care
The Midlife Women's Health 2025 course is led by a multidisciplinary group of experts from Massachusetts General Hospital who will present on the evaluation and management of osteoporosis, gastrointestinal malignancy, stress, obesity, substance use disorder, anxiety, sexual dysfunction, breast cancer, and menopausal hormone therapy to assist clinicians in caring for their midlife patients.
Brain mechanisms of vagus nerve stimulation and stress reduction training for migraine
The study involves multiple visits over 6 months. You will complete an 8-week stress reduction treatment that includes a medical device worn in the ear and attend MRI and PET scans. You will also complete daily migraine diaries online.
Multimodal profiling of stress-induced immune reprogramming in cardiovascular participants
The purpose of this research study is to learn about the effects of stress on the brain and disease of the heart and blood vessels (cardiovascular disease or CVD).
