-
Featured
Transcatheter Arterialization of Deep Veins Safe, Successful for No-Option Chronic Limb-threatening Ischemia
Anahita Dua, MD, MBA, MSc, and colleagues found that transcatheter arterialization of the deep veins was safe and could be performed with a high degree of procedural success in patients with chronic limb-threatening ischemia who had no conventional revascularization options and would likely be amputated.
-
Large, International Study Identifies Genes and Causal Mechanisms for Coronary Artery Disease
Krishna G. Aragam, MD, MS, and colleagues in the CARDIoGRAMplusC4D Consortium developed a novel framework for determining causal variants, genes, and mechanistic pathways in coronary artery disease, which could enhance research into other diseases involving genome-wide association studies.
-
Use of High-sensitivity Cardiac Troponin Assays Would Benefit U.S. Hospitals
As of September 2021, only 33% of U.S. hospitals used high-sensitivity cardiac troponin assays, Massachusetts General Hospital researchers found. Yet, the assays are linked to modestly shorter length of stay, no increase in in-hospital mortality, and less use of invasive angiography to evaluate low-risk chest pain.
-
New Model Uses Ordinary Clinical Data to Estimate Ascending Aortic Diameter in Asymptomatic Individuals
Patrick T. Ellinor, MD, PhD, James P. Pirruccello, MD, and colleagues have developed an online calculator based on common demographic and clinical characteristics that estimates thoracic aortic diameter in asymptomatic patients, and thus may predict aortic dissection and rupture.
-
Innovative Procedure for Peripheral Artery Disease: Q&A With Dr. Anahita Dua, MBChB, MBA, MSc
Diabetes can cause peripheral artery disease, where blood flow to the legs and feet is reduced. These patients typically have amputations. Mass General researchers, including Anahita Dua, MBChB, MBA, MSc, are using a new, cutting-edge procedure to direct oxygenated blood to the foot, reducing the need for amputation.
-
Polygenic Risk Score Identifies Individuals at Risk of Thoracic Aortic Aneurysm
James P. Pirruccello, MD, Patrick T. Ellinor, MD, PhD, Mark Lindsay, MD, PhD, and colleagues used artificial intelligence to reveal the genetic basis of aortic size variation, then built a polygenic risk score that predicted future risk of thoracic aortic aneurysm. Their findings may also point to new therapeutic targets.
Aortic Disease Contributors
-
Eric Michael Isselbacher, MD
Director, Healthcare Transformation Lab, Co-Director, Mass General Thoracic Aortic Center
Recent Article
Thoracic Aortic Aneurysms: Prevention, Diagnosis and Treatment
-
Mark E. Lindsay, MD, PhD
Cardiologist, Massachusetts General Hospital and Mass General for Children, Assistant Professor of Medicine, Harvard Medical School
Recent Article
Rare Smooth Muscle Disorder Traced to a Single Mutation in a Non-coding Gene
-
Mark F. Conrad, MD
Director of Clinical Research, Division of Vascular and Endovascular Surgery, Assistant Program Director, Division of Vascular and Endovascular Surgery
Recent Article
Adverse Neck Anatomy Increases Risk of Late Type 1A Endoleaks
Cardiovascular Care at Mass General
At Mass General, our world-class physicians and nurses specialize in specific forms of both heart and vascular disease, and work closely together to offer leading treatments and preventive care for cardiovascular conditions.