Posts by James P. Pirruccello, MD
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New Model Uses Ordinary Clinical Data to Estimate Ascending Aortic Diameter in Asymptomatic Individuals
Patrick T. Ellinor, MD, PhD, James P. Pirruccello, MD, and colleagues have developed an online calculator based on common demographic and clinical characteristics that estimates thoracic aortic diameter in asymptomatic patients, and thus may predict aortic dissection and rupture.
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Polygenic Risk Score Identifies Individuals at Risk of Thoracic Aortic Aneurysm
James P. Pirruccello, MD, Patrick T. Ellinor, MD, PhD, Mark Lindsay, MD, PhD, and colleagues used artificial intelligence to reveal the genetic basis of aortic size variation, then built a polygenic risk score that predicted future risk of thoracic aortic aneurysm. Their findings may also point to new therapeutic targets.
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Polygenic Score Predicts Risk of Dilated Cardiomyopathy
Common genetic polymorphisms associated with left ventricular structure and function contribute to the risk of dilated cardiomyopathy.
Biography
James P. Pirruccello, MD, is a cardiologist at Massachusetts General Hospital.
Cardiovascular Care at Mass General
At Mass General, our world-class physicians and nurses specialize in specific forms of both heart and vascular disease, and work closely together to offer leading treatments and preventive care for cardiovascular conditions.